Results 21 to 30 of about 50,365 (196)

Atorvastatin (Lipitor) by MCR [PDF]

ACS Medicinal Chemistry Letters, 2019
A concise and convergent synthesis of the atorvastatin, the best-selling cardiovascular drug of all time, is presented. Our approach is based on an Ugi reaction, which shortens the current synthetic route and is advantageous over the published syntheses.
Tryfon Zarganes-Tzitzikas, Constantinos G. Neochoritis, Alexander Dömling   +2 more
openaire   +3 more sources

Characterization of two novel colistin resistance gene mcr-1 variants originated from Moraxella spp.

Frontiers in Microbiology, 2023
This study aimed to characterize two novel mcr-1 variants, mcr-1.35 and mcr-1.36, which originated from Moraxella spp. that were isolated from diseased pigs in China. The Moraxella spp.
Yongliang Che, Yongliang Che, Renjie Wu, Renjie Wu, Hongjie Li, Longbai Wang, Longbai Wang, Xuemin Wu, Xuemin Wu, Qiuyong Chen, Qiuyong Chen, Rujing Chen, Rujing Chen, Lunjiang Zhou, Lunjiang Zhou   +14 more
doaj   +1 more source

Plasmid maps of pACYC-Para-MCR-1 and pACYC-NP-MCR-1.

, 2023
The plasmid for expressing MCR-1 or M6 under the regulation of arabinose promoter was shown as (A), and the one for expressing target proteins under the regulation of MCR-1 native promoter was shown as (B).
Chenchen Zhang (324804), Siyuan Feng (5998040), Yaxin Li (312731), Lingxuan Lyu (17628265), Yohei Doi (188766), Wanfei Liang (8610954), Fang Bai (1612534), Lin Wang (11986), Lan-Lan Zhong (9702537), Dianrong Zhou (11816537), Jiachen Li (669381), Hui Zhao (7395), Yong Chen (109188), Nicole Stoesser (220513), Guo-Bao Tian (3365051), Lujie Liang (8610960), Wenjing Wei (525144)   +16 more
core   +1 more source

Prevalence and molecular epidemiology of mcr-mediated colistin-resistance Escherichia coli from healthy poultry in France after national plan to reduce exposure to colistin in farm

Frontiers in Microbiology, 2023
IntroductionWithin the 2007–2014 programme for the surveillance of antimicrobial resistance (AMR) in livestock in France, mcr-1 prevalence average in commensal Escherichia coli was found to be 5.9% in turkeys and 1.8% in broilers, indicating that mobile ...
Agnès Perrin-Guyomard, Paméla Houée, Pierrick Lucas, Arnaud Felten, Laetitia Le Devendec, Claire Chauvin, Isabelle Kempf   +6 more
doaj   +1 more source

mcr-1 regulatory variants

, 2023
Associated paper:    Regulatory fine-tuning and horizontal gene transfer stabilize mobile colistin resistance  Lois Ogunlana, Liam P. Shaw, Divjot Kaur, Pramod Jangir, Timothy Walsh, Stephan Uphoff, and R.C. MacLean.  Preprint version: https://doi.org/10.
Liam Shaw (5487083)
core   +1 more source

Antimicrobial resistance profiles of Escherichia coli from swine farms using different antimicrobials and management systems [PDF]

Veterinary World, 2021
Background and Aim: The emerging of antimicrobial-resistant foodborne bacteria is a serious public health concern worldwide. This study was conducted to determine the association between farm management systems and antimicrobial resistance profiles of ...
Pramualchai Ketkhao, Sukanya Thongratsakul, Pariwat Poolperm, Chaithep Poolkhet, Patamabhorn Amavisit   +4 more
doaj   +1 more source

MCR: modern colistin resistance [PDF]

European Journal of Clinical Microbiology & Infectious Diseases, 2016
Recently, plasmid-mediated and, therefore, transferable bacterial polymyxin resistance was discovered in strains from both humans and animals. Such a trait may widely spread geographically, while simultaneously crossing microbial species barriers. This may ultimately render the "last resort" polymyxin antibiotics therapeutically useless.
Caniaux I, van Belkum A, Zambardi G, Poirel L, Gros MF   +4 more
openaire   +4 more sources

Modelación de la respuesta hidrológica al cambio climático: experiencias de dos cuencas de la zona centro-sur de Chile

Tecnología y ciencias del agua, 2010
Durante los últimos años se ha observado un cambio progresivo de las condiciones climáticas en el mundo, que ha tenido como consecuencia aumentos de la frecuencia y severidad de fenómenos, como inundaciones y sequías. Por lo anterior, es necesario contar
Alejandra Stehr, Patrick Debels, José Luis Arumi, Hernán Alcayaga, Francisco Romero   +4 more
doaj   +1 more source

Bacteria from Animals as a Pool of Antimicrobial Resistance Genes

Antibiotics, 2017
Antimicrobial agents are used in both veterinary and human medicine. The intensive use of antimicrobials in animals may promote the fixation of antimicrobial resistance genes in bacteria, which may be zoonotic or capable to transfer these genes to human ...
Maria Angeles Argudín, Ariane Deplano, Alaeddine Meghraoui, Magali Dodémont, Amelie Heinrichs, Olivier Denis, Claire Nonhoff, Sandrine Roisin   +7 more
doaj   +1 more source

Research Note: Longitudinal fecal shedding patterns and characterization of Salmonella enterica and mcr-positive Escherichia coli in meat-type ducks raised in an open-house system

Poultry Science, 2022
: This longitudinal study aimed to determine the fecal shedding pattern and characterize Salmonella enterica and mcr-positive Escherichia coli from meat-type ducks raised in an open-house system in Thailand.
Kanit Assawatheptawee, Phiraphat Punyadi, Taradon Luangtongkum, Pannika R. Niumsup   +3 more
doaj   +1 more source