Detection and characterization of ESBL-producing Escherichia coli and additional co-existence with mcr genes from river water in northern Thailand [PDF]
Background Extended-spectrum β-lactamase producing Escherichia coli (ESBL-producing E. coli) have emerged, causing human and animal infections worldwide.
Kamonnaree Chotinantakul +2 more
doaj +2 more sources
Global burden of colistin-resistant bacteria : mobilized colistin resistance genes study (1980-2018) [PDF]
Colistin is considered to be an antimicrobial of last-resort for the treatment of multidrug-resistant Gram-negative bacterial infections. The recent global dissemination of mobilized colistin resistance (mcr) genes is an urgent public health threat.
Elbediwi, Mohammed +10 more
core +1 more source
Epidemiological and genomic characteristics of global mcr-positive Escherichia coli isolates
ObjectiveThe worldwide dissemination of colistin-resistant Escherichia coli (E. coli) endangers public health. This study aimed to better understand the global genomic epidemiology of E.
Jiping Shi +6 more
doaj +1 more source
Selection and validation of potato candidate genes for maturity corrected resistance to Phytophthora infestans based on differential expression combined with SNP association and linkage mapping. [PDF]
Late blight of potato (Solanum tuberosum L.) caused by the oomycete Phytophthora infestans (Mont.) de Bary, is one of the most important bottlenecks of potato production worldwide.
Gebhardt, C. +3 more
core +3 more sources
Effect of Different Media on the Bactericidal Activity of Colistin and on the Synergistic Combination With Azidothymidine Against mcr-1-Positive Colistin-Resistant Escherichia coli [PDF]
Antimicrobial susceptibility testing (AST) performed according to defined guidelines is important to identify resistance and to predict the clinical success or failure of specific antibiotic therapy.
Coates, A +4 more
core +1 more source
Durante los últimos años se ha observado un cambio progresivo de las condiciones climáticas en el mundo, que ha tenido como consecuencia aumentos de la frecuencia y severidad de fenómenos, como inundaciones y sequías. Por lo anterior, es necesario contar
Alejandra Stehr +4 more
doaj +1 more source
Epidemiology of mobile colistin resistance genes mcr-1 to mcr-9
Abstract The identification of the first mobile colistin resistance (MCR) gene, mcr-1, in 2015 triggered a rash of mcr screening reports. Subsequently, nine MCR-family genes and their variants have been described. However, a comprehensive overview concerning the epidemiology of the whole MCR family, which is essential for facilitating ...
Zhuoren, Ling +5 more
openaire +2 more sources
Bacteria from Animals as a Pool of Antimicrobial Resistance Genes
Antimicrobial agents are used in both veterinary and human medicine. The intensive use of antimicrobials in animals may promote the fixation of antimicrobial resistance genes in bacteria, which may be zoonotic or capable to transfer these genes to human ...
Maria Angeles Argudín +7 more
doaj +1 more source
BackgroundOver the last two decades, the prevalence of colistin resistance among the members of Enterobacteriaceae has been increasing, particularly among Klebsiella pneumoniae isolates; this limits the potential use of colistin and leads to worsened ...
Yanling Liu +10 more
doaj +1 more source
Molecular insights into functional differences between mcr-3- and mcr-1-mediated colistin resistance [PDF]
The global emergence of plasmid-mediated colistin resistance genes mcr-1 and mcr-3 has threatened the role of the “last resort” drug colistin in the defense against infections caused by multidrug-resistant Gram-negative bacteria.
Li, Hui +8 more
core +2 more sources

