Results 31 to 40 of about 2,342 (259)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

High-Quality Spherical Silver Alloy Powder for Laser Powder Bed Fusion Using Plasma Rotating Electrode Process

Micromachines
The plasma rotating electrode process (PREP) is an ideal method for the preparation of metal powders such as nickel-based, titanium-based, and iron-based alloys due to its low material loss and good degree of sphericity.
Hao Li, Shenghuan Zhang, Qiaoyu Chen, Zhaoyang Du, Xingyu Chen, Xiaodan Chen, Shiyi Zhou, Shuwen Mei, Linda Ke, Qinglei Sun, Zuowei Yin, Jie Yin, Zheng Li   +12 more
doaj   +1 more source

Experimental investigation for influence of sand temperature and sand binder on strength of furan no-bake mould system

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2018
Though the casting process is also known as a process of uncertainty, in the present study, an attempt has been made to investigate the effect of sand temperature, amount of resin and amount of catalyst on compressive strength and scratch hardness of the
Shailee G. ACHARYA, Jeetendra A. VADHER
doaj   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Fabrication of WC-TiC-6%Co Hard Metals by micro-powder injection moulding [PDF]

Proceedings of the 2015 2nd International Workshop on Materials Engineering and Computer Sciences, 2015
Micro-powder injection moulding (MIM) is the fastest growing technology within the powder metallurgy area.The reason for this growth is that it is an efficient production method. In this work, the fabrication of WC-TiC-6% was studied. The result showed that Solvent debinding + thermal debinding was efficient to dislodge binders with no influence on the
Quan Li, Bo Wen, Aimin Jiang
openaire   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Performance analysis of cow dung as an eco-friendly additive material for sustainable moulding and casting

China Foundry, 2019
In the present work, an attempt is made to partially replace high cost silica sand with sustainable eco-friendly cow-dung. The practical utility of cow dung as an additive material that facilitates binding in sand moulds has been tested.
Manjunath Patel G C, Kapil Gupta, Ganesh Chate   +2 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Experimental investigation and optimization of compression moulding parameters for MWCNT/glass/kevlar/epoxy composites on mechanical and tribological properties

Journal of Materials Research and Technology, 2021
The mechanical properties of hybrid composites are largely influenced by the reinforcing fibres, nanofillers, matrix materials and fabrication methods. Multi-wall carbon nanotubes (MWCNTs) fillers reinforced to E-glass/Kevlar/epoxy composites (GKEC) are ...
Hanumantharaya Rangaswamy, Harsha H. M, Manjunath Patel Gowdru Chandrashekarappa, Danil Yu Pimenov, Khaled Giasin, Szymon Wojciechowski   +5 more
doaj   +1 more source