Results 211 to 220 of about 4,518,026 (355)

The beneficial effects of ethanolic extract of Sargassum serratifolium in DNCB-induced mouse model of atopic dermatitis [PDF]

Myeong‐Jin Kim, Heeyeon Ryu, Hyeon Hak Jeong, Ji Yun Van, Ji Young Hwang, Ah-reum Kim, Jaeseong Seo, Kyoung Mi Moon, Won‐Kyo Jung, Bonggi Lee   +9 more
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Dual recombinase-mediated endothelial cell-specific lineage tracing and ablation. [PDF]

Cell Regen
Li J, Zhang M, Liu X, Zhang Z, Shi M, Pu W, Zhou B.   +6 more
europepmc   +1 more source

Sympatric mouse lemurs in north-west Madagascar: A new rufous mouse lemur species (Microcebus ravelobensis) [PDF]

, 1998
Cepok, Sabine, Radespiel, Ute, Rakotoarison, Nasolo, Zietemann, Vera, Zimmermann, Elke   +4 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

A scalable two-step genome editing strategy for generating full-length gene-humanized mice at diverse genomic loci. [PDF]

Nat Commun
Taguchi J, Kikuchi M, Jeon H, Shimizu R, Mori H, Ikawa M, Yamada Y, Sato K, Ikeda T, Yamazaki S, Ozawa M.   +10 more
europepmc   +1 more source

A Study of the Effects of Electroporation on Skin in an In-Vivo Mouse Model [PDF]

Yu Zhang, Zheng Fang, H. M. Dai, Bing Zhang   +3 more
openalex   +1 more source

Inhibition of Glycogen Synthase II with RNAi Prevents Liver Injury in Mouse Models of Glycogen Storage Diseases [PDF]

, 2018
Natalie W. Pursell, Jessica J. Gierut, Wei Zhou, Michael Dills, Rohan Diwanji, Monika Gjorgjieva, Utsav Saxena, Jr-Shiuan Yang, Anee Shah, Nandini Venkat, Rachel Storr, Bo Young Kim, Weimin Wang, Marc Abrams, Margaux Raffin, Gilles Mithieux, Fabienne Rajas, Henryk Dudek, Bob D. Brown, Cheng-Jung Lai   +19 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Conplastic FVB/N-mt129S6/SvEvTac mice: A new tool for cancer research. [PDF]

PLoS One
Gruzdev A, Jefferson WN, Hagler TB, Scott GJ, Ray MK, Muse GW, Sellers RS, Williams CJ.   +7 more
europepmc   +1 more source