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Current Protocols in Mouse Biology, 2015
AbstractNecropsy (also known as autopsy) is the post‐mortem dissection of bodies after euthanasia or death and is a scientific examination conducted to observe and dissect the organs, collect tissues, and determine the extent of grossly evident disease. Research necropsies are conducted to obtain specific samples tailored according to study objectives.
Piper M, Treuting, Jessica M, Snyder
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AbstractNecropsy (also known as autopsy) is the post‐mortem dissection of bodies after euthanasia or death and is a scientific examination conducted to observe and dissect the organs, collect tissues, and determine the extent of grossly evident disease. Research necropsies are conducted to obtain specific samples tailored according to study objectives.
Piper M, Treuting, Jessica M, Snyder
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American Journal of Physiology-Legacy Content, 1957
Normal adult male mice of various strains excreted 0.6–3.1 mg of urinary protein N/day; females, considerably less. Electrophoretic measurements showed the protein to consist of three components, all having negative mobilities (–7.5 to –8.3 cm2/volt/sec x 10–5 at ph 8.5) greater than that of mouse serum albumin (–6.3 ± 0.1 cm2/ volt/sec.
J S, Finlayson, C A, Baumann
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Normal adult male mice of various strains excreted 0.6–3.1 mg of urinary protein N/day; females, considerably less. Electrophoretic measurements showed the protein to consist of three components, all having negative mobilities (–7.5 to –8.3 cm2/volt/sec x 10–5 at ph 8.5) greater than that of mouse serum albumin (–6.3 ± 0.1 cm2/ volt/sec.
J S, Finlayson, C A, Baumann
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Methods, 2011
Model organisms like the mouse are important tools to learn more about gene function in man. Within the last 20 years many mutant mouse lines have been generated by different methods such as ENU mutagenesis, constitutive and conditional knock-out approaches, knock-down, introduction of human genes, and knock-in techniques, thus creating models which ...
Helmut, Fuchs +49 more
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Model organisms like the mouse are important tools to learn more about gene function in man. Within the last 20 years many mutant mouse lines have been generated by different methods such as ENU mutagenesis, constitutive and conditional knock-out approaches, knock-down, introduction of human genes, and knock-in techniques, thus creating models which ...
Helmut, Fuchs +49 more
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The Journal of Immunology, 1976
Abstract The addition of PHA to C3H mouse spleen cells in tissue culture led to the production of lymphotoxin (LT). Cytotoxicity was assayed by addition of the culture fluids to syngeneic target cells labeled with tritiated thymidine; after an incubation period of 72 hr the amount of radioactivity released into the supernatant was ...
G, Trivers, D, Braungart, E J, Leonard
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Abstract The addition of PHA to C3H mouse spleen cells in tissue culture led to the production of lymphotoxin (LT). Cytotoxicity was assayed by addition of the culture fluids to syngeneic target cells labeled with tritiated thymidine; after an incubation period of 72 hr the amount of radioactivity released into the supernatant was ...
G, Trivers, D, Braungart, E J, Leonard
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2018
Genotyping is an invaluable tool for identifying organisms carrying genetic variations including insertions and deletions. This method involves the extraction of DNA from animal tissue samples and subsequent amplification of genomic regions of interest by polymerase chain reaction (PCR).
Sandra, Vuong, Paul, Delgado-Olguin
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Genotyping is an invaluable tool for identifying organisms carrying genetic variations including insertions and deletions. This method involves the extraction of DNA from animal tissue samples and subsequent amplification of genomic regions of interest by polymerase chain reaction (PCR).
Sandra, Vuong, Paul, Delgado-Olguin
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Diabetes Research and Clinical Practice, 1994
The KK mouse strain shows inherently glucose intolerance and insulin resistance. When KK mice become obese by aging, dietary means or other ways, such a chemical diabetic state is changed to overt diabetic state associated with frank hyperglycemia and glucosuria.
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The KK mouse strain shows inherently glucose intolerance and insulin resistance. When KK mice become obese by aging, dietary means or other ways, such a chemical diabetic state is changed to overt diabetic state associated with frank hyperglycemia and glucosuria.
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Blood, 2009
Abstract In this issue of Blood, ter Brugge and colleagues describe the results of their efforts to express SV40 T antigen in mature B cells of mice.1 As a consequence of T antigen expression, B cells develop normally but, upon aging, mice show an accumulation of monoclonal CD5+ B cells and have a chronic lymphocytic leukemia-like ...
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Abstract In this issue of Blood, ter Brugge and colleagues describe the results of their efforts to express SV40 T antigen in mature B cells of mice.1 As a consequence of T antigen expression, B cells develop normally but, upon aging, mice show an accumulation of monoclonal CD5+ B cells and have a chronic lymphocytic leukemia-like ...
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Mammalian Genome, 1992
As of October 1996, there were 444 loci mapped to Chr 18 in the mouse (Table 1); 110 identified as genes or gene-related sequences and 334 identified as anonymous DNA sequences. Since last year's report, 67 new loci were added; 21 identified as genes and 47 identified as DNA segments.
Johnson, K R, Davisson, M T
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As of October 1996, there were 444 loci mapped to Chr 18 in the mouse (Table 1); 110 identified as genes or gene-related sequences and 334 identified as anonymous DNA sequences. Since last year's report, 67 new loci were added; 21 identified as genes and 47 identified as DNA segments.
Johnson, K R, Davisson, M T
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1995
Abstract To most people, all small rodents are virtually indistinguishable from each other, and as such, they are lumped together and considered to be mice of one kind or another. In Webster’s Third New International Dictionary, one finds the following definition for a mouse: “any of numerous small rodents typically resembling ...
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Abstract To most people, all small rodents are virtually indistinguishable from each other, and as such, they are lumped together and considered to be mice of one kind or another. In Webster’s Third New International Dictionary, one finds the following definition for a mouse: “any of numerous small rodents typically resembling ...
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Mammalian Genome, 1991
The information about each locus for a chromosome appears on one line of the map. At the left is a small figure of the whole chromosome. A box on the chromosome figure indicates which portion of the chromosome is expanded for view on that page. To the right of the small figure is the corresponding expanded centimorgan scale.
C A, Kozak, D A, Stephenson
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The information about each locus for a chromosome appears on one line of the map. At the left is a small figure of the whole chromosome. A box on the chromosome figure indicates which portion of the chromosome is expanded for view on that page. To the right of the small figure is the corresponding expanded centimorgan scale.
C A, Kozak, D A, Stephenson
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