Results 251 to 260 of about 2,409,641 (315)

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

Principles for Dendritic Spine Size and Density in Human and Mouse Cortical Pyramidal Neurons. [PDF]

J Comp Neurol
Benavides-Piccione R, Fernaud-Espinosa I, Kastanauskaite A, DeFelipe J.   +3 more
europepmc   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Enhancing breast Cancer immunotherapy using gold nanoparticles carrying tumor antigens. [PDF]

Sci Rep
Javadi MM, Soleimani N, Zandi A.
europepmc   +1 more source

Further Tests for Tumour-Initiating Activity: N,N-DI-(2-Chloroethyl)-P-Aminophenylbutyric Acid (CB1348) as an Initiator of Skin Tumour Formation in the Mouse

, 1956
M. H. Salaman, F. J. C. Roe
openalex   +2 more sources

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

Aging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

RNA polymerase I is essential for driving the formation of 3D genome in early embryonic development in mouse, but not in human. [PDF]

Genome Med
Hou C, Tian GG, Hu S, Chen B, Li X, Xu B, Cao Y, Le W, Hu R, Chen H, Zhang Y, Fang Q, Zhang M, Wang Z, Zhang Z, Zhang J, Wei Z, Yao G, Wang Y, Yin P, Guo Y, Tong G, Teng X, Sun Y, Cao Y, Wu J.   +25 more
europepmc   +1 more source

Studies on Co-carcinogenesis. SH-Reactors and other Substances Tested for Co-carcinogenic action in Mouse Skin

, 1953
R H Gwynn, M. H. Salaman
openalex   +1 more source

Developing reference plans for evaluating global clinical trials credentialing and PSQA systems

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To develop a practical framework for creating a diverse set of validated reference plans (varying in complexity) and implement a workflow to introduce beam modeling, calibration, and delivery errors into the reference cohort to test and compare various dosimetry audit methodologies.
Fre'Etta M. D. Brooks, Mohammad Hussein, Jessica Lye, Christopher L. Nelson, Nakamura Mitsuhiro, Mallory C. Glenn, Patricia Diez, Rushil Patel, Maddison Shaw, Ileana Silvestre Patallo, Miriam Barry, Catharine H. Clark, Joerg Lehmann, Stephen F. Kry   +13 more
wiley   +1 more source

OrthologAL: a Shiny application for quality-aware humanization of non-human pre-clinical high-dimensional gene expression data. [PDF]

Bioinformatics
Chowdary R, Suter RK, D'Antuono M, Gomes C, Stein J, Lee KB, Lee JK, Ayad NG.   +7 more
europepmc   +1 more source