Results 271 to 280 of about 2,409,641 (315)

Inhibition of Talin2 dedifferentiates myofibroblasts and reverses lung and kidney fibrosis. [PDF]

Sci Rep
White MJV, Ozkan M, Medellin JEG, Solanki A, Hubbell JA.   +4 more
europepmc   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Targeting mechanistic target of rapamycin complex 2 attenuates immunopathology in systemic lupus erythematosus. [PDF]

Rheumatology (Oxford)
Ai M, Zhou X, Carrer M, Jafar-Nejad P, Li Y, Gades N, Alexander M, Bautista-Vargas M, Duarte-García A, Zeng H.   +9 more
europepmc   +1 more source

Herbal Formula Yi‐Fei‐Jie‐Du‐Tang Regulates Epithelial‐Mesenchymal Transition and Vasculogenic Mimicry in Lung Cancer via HIF1A‐Mediated Ferroptosis

Advanced Biology, Volume 9, Issue 3, March 2025.
Yi‐Fei‐Jie‐Du‐Tang (YFJDT), a traditional Chinese medicine, has shown potential in lung cancer treatment by targeting key pathways. This study explores the mechanisms of YFJDT using bioinformatics, xenograft models, and A549 cells, demonstrating that YFJDT downregulates HIF1A, promotes ferroptosis, and inhibits epithelial‐mesenchymal transition (EMT ...
Shanshan Wang, Die Yang, Chengjia Yuan, Yang Wu, Qingying Wang, Yongjian Wu, Xiaochun Zhang   +6 more
wiley   +1 more source

Tumor microenvironment remodeling with a telomere-targeting agent and its cooperative antitumor effects with a nanovaccine. [PDF]

J Nanobiotechnology
Bai J, Wang M, Luo Y, Duan B, Yang Y, Fu Y, Li S, Yang Z, Zheng P, Yu T, Yin X, Bai H, Long Q, Ma Y.   +13 more
europepmc   +1 more source

Survey of transcriptome analyses of hippocampal neurogenesis with focus on adult dentate gyrus stem cells. [PDF]

Front Cell Dev Biol
Micheli L, Caruso M, D'Andrea G, Volpe D, Ceccarelli M, Tirone F.   +5 more
europepmc   +1 more source

Reply to Letter: Real‐World Clinical Experience With Serum MOG and AQP4 Antibody Testing by Live Versus Fixed Cell‐Based Assay

Annals of Clinical and Translational Neurology, EarlyView.
Yana Said, Conlan Tran, LuAnn Rezavi, Patrizio Caturegli, Eoin P. Flanagan, Elias S. Sotirchos   +5 more
wiley   +1 more source

Development of SNAP-Tag Based Nanobodies as Secondary Antibody Mimics for Indirect Immunofluorescence Assays. [PDF]

Cells
Sheng W, Zhang C, Mohiuddin TM, Al-Rawe M, Schmitz R, Niebert M, Konrad L, Wagner S, Zeppernick F, Meinhold-Heerlein I, Hussain AF.   +10 more
europepmc   +1 more source