Results 51 to 60 of about 2,582,892 (293)

The Nucleoprotein and Phosphoprotein of Peste des Petits Ruminants Virus Inhibit Interferons Signaling by Blocking the JAK-STAT Pathway

Viruses, 2019
Peste des petits ruminants virus (PPRV) is associated with global peste des petits ruminants resulting in severe economic loss. Peste des petits ruminants virus dampens host interferon-based signaling pathways through multiple mechanisms.
Pengfei Li, Zixiang Zhu, Xiangle Zhang, Wen Dang, Linlin Li, Xiaoli Du, Miaotao Zhang, Chunyan Wu, Qinghong Xue, Xiangtao Liu, Haixue Zheng, Yuchen Nan   +11 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Persian Medicinal Plants for Oral Diseases: Investigated in Fars Province [PDF]

Research Journal of Pharmacognosy
Background and objectives: This study seeks to document the traditional knowledge of medicinal plants from Fars Province, Iran, used in the treatment of common oral diseases.
Majid Zia-Behbahani, Alireza Barzegar, Farzane Farahmand, Mostafa Rezaee, Sedigheh Khademian, Hosein Niknahad, Abdolali Mohagheghzadeh*   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Oral Lesions in Elderly Patients in Referral Centers for Oral Lesions of Bahia

International Archives of Otorhinolaryngology, 2015
Introduction The aging population phenomenon is occurring on a global scale; aging affects all of the structures of organisms, including the oral cavity.
Sarah Souza, Técia Alves, Jean Santos, Márcio Oliveira   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A chemiluminescence immunoassay for detecting neutralizing antibodies of foot-and-mouth disease virus serotype A

Applied Microbiology and Biotechnology
Foot-and-mouth disease (FMD) is a highly contagious viral disease affecting cloven-hoofed animals, posing significant threats to global livestock industries.
Mengyang Sun, Yanfang Bao, Kun Li, Yili Zuo, Huiyan Zhang, Yuanfang Fu, Pinghua Li, Pu Sun, Zhixun Zhao, Tao Jiang, Xingwen Bai, Mi Lin, Zengjun Lu, Yimei Cao   +13 more
doaj   +1 more source

Sheep Movement Networks and the Transmission of Infectious Diseases [PDF]

, 2010
Background and Methodology: Various approaches have been used to investigate how properties of farm contact networks impact on the transmission of infectious diseases.
Nicholas J. Savill, Nicholas J Savill, Woolhouse Mark E. J., Mark E J Woolhouse, Volkova Victoriya V., Savill, Nicholas J., Howey Richard, Savill Nicholas J., Mark E. J. Woolhouse, Howey, Richard, Victoriya V Volkova, Victoriya V. Volkova, Volkova, Victoriya V., Richard Howey, Woolhouse, Mark E. J.; id_orcid   +14 more
core   +2 more sources