Results 71 to 80 of about 10,713 (254)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Tolerance to mutations in the foot-and-mouth disease virus integrin-binding RGD region is different in cultured cells and in vivo and depends on the capsid sequence context. [PDF]
Engineered RNAs carrying substitutions in the integrin receptor-binding Arg-Gly-Asp (RGD) region of foot-and-mouth disease virus (FMDV) were constructed (aa 141-147 of VP1 capsid protein) and their infectivity was assayed in cultured cells and suckling
Pulido, M. R. +15 more
core +1 more source
Removable denture-related oral mucosal lesions: descriptive clinical study
Objective: The aim of this study was to investigate whether there was a relationship between removable denture-related oral mucosal lesions and denture type, and demographic characteristics.
Gökçen Akçiçek +2 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
A Bayesian inference framework to reconstruct transmission trees using epidemiological and genetic data [PDF]
The accurate identification of the route of transmission taken by an infectious agent through a host population is critical to understanding its epidemiology and informing measures for its control. However, reconstruction of transmission routes during an
King, D.P. +33 more
core +1 more source
Introducción: A las consultas del servicio de estomatología general integral y de urgencia de la Clínica Estomatológica Docente 27 de Noviembre, del municipio Colón, acuden pacientes con síntomas y signos relacionados con algunas de las entidades ...
Doris del Rosario Soto Caballero +3 more
doaj
Prevalence of oral lesions in Brazilian patients with tuberculosis
Background : Oral lesions of tuberculosis (TB) are rare and usually associated with the secondary form of the disease. Aim : The aim of the present study was to determine the prevalence of oral lesions in a cohort of TB-infected individuals.
Rodolfo Albuquerque Santiago +5 more
doaj +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Impact assessment of an independent agency for animal health in England [PDF]
The applicability of a stochastic model was explored to assess the impact of a new independent agency for animal health in England in terms of the cost of animal disease outbreaks.
Rocks, Sophie A. +3 more
core +1 more source

