Results 61 to 70 of about 2,582,892 (293)
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Background: In India, people commonly approach pharmacies rather than health professionals for their common ailments including oral health problems. Aim: To assess the type of medication and advice to clients without prescription provided for common oral
Savithra Prakash +2 more
doaj +1 more source
Risk of foot-and-mouth disease spread due to sole occupancy authorities and linked cattle holdings [PDF]
Livestock movements in Great Britain are well recorded, have been extensively analysed with respect to their role in disease spread, and have been used in real time to advise governments on the control of infectious diseases.
O'Hare, Anthony +27 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
INFECTIOUS DISEASES OF THE MOUTH OF THE MOUTH
This article addresses issues such as infection, what it is and how it is transmitted, and the diseases that can occur in the mucous membranes of the oral cavity.
Raimjonov Rustamjon Ravshanbek o’g’li +1 more
openaire +1 more source
The epidemiology of foot-and-mouth disease in the kingdom of Bhutan [PDF]
Foot-and-mouth disease (FMD) is a highly infectious viral disease of all cloven-hoofed animals. It can have a significant impact on the livelihood of livestock owners, especially in developing nations such as Bhutan.
Dukpa, Kinzang
core
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Risk based culling for highly infectious diseases of livestock [PDF]
The control of highly infectious diseases of livestock such as classical swine fever, foot-and-mouth disease, and avian influenza is fraught with ethical, economic, and public health dilemmas.
van Boven, M. +22 more
core +3 more sources

