Results 61 to 70 of about 10,713 (254)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Feet in mouth disease.

Genome biology, 2005
We can, and should, use the financial resources of our institutions to redress the serious inequities and problems that bright, ambitious women face in the scientific workplace.
openaire   +2 more sources

Correlação entre os diagnósticos citopatológicos e histopatológicos das lesões da mucosa oral após a punção aspirativa por agulha fina

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Fazer um estudo retrospectivo, correlacionando os diagnósticos citopatológicos obtidos por punção aspirativa por agulha fina (PAAF) com os diagnósticos histopatológicos de lesões da região bucomaxilofacial, de pacientes que foram atendidos no ...
Tatiana Ferreira Robaina, Antonio Carlos de Azeredo Coutinho, Carla Peixoto Valladares, Eliane Pedra Dias, Simone de Queiroz Chaves Lourenço   +4 more
doaj   +1 more source

Relationship between clinical and laboratory findings of rheumatoid arthritis patients with their oral status and disease activity

Caspian Journal of Internal Medicine, 2021
Background: Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease. Complications of RA can cause low quality of life and disabilities. Nowadays, despite all the medical developments, etiology of RA is unclear. Both soft and hard
Simin Almasi, Mahnaz Karbalaei sabbagh, Dorsa Barzi, Azadeh Tahooni, Hosein Atyabi, Samira Basir Shabestari   +5 more
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Use and abuse of mathematical models: an illustration from the 2001 foot and mouth disease epidemic in the United Kingdom

, 2006
Foot and mouth disease (FMD) is a major threat, not only to countries whose economies rely on agricultural exports, but also to industrialised countries that maintain a healthy domestic livestock industry by eliminating major infectious diseases from ...
Thrusfield, M., Thrusfield, Michael, Kitching, R. P., Taylor, Nick M, Taylor, N. M., Kitching, Richard P   +5 more
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Mucocele of the lower lip mucosa [PDF]

RGO: Revista Gaúcha de Odontologia, 2008
Mucocele, also known as mucous extravasation phenomenon, is a pseudocyst of traumatic etiology, in which a minor salivary gland ductruptures. Clinically it can be observed as a tumefaction or bubble; it is flaccid on palpation, asymptomatic, with a ...
Tais Frenzel da Rosa, Anna Luisa Tellechea da Silva, Karen Martins Kaiser, Maurício Assunção Pereira   +3 more
doaj  

A rare case report of orofacial granulomatosis in a pediatric patient

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2012
Orofacial granulomatosis comprises a group of diseases characterized by noncaseating granulomatous inflammation affecting the soft tissues of the oral and maxillofacial region.
P Singhal, G D Chandan, U M Das, A Singhal   +3 more
doaj   +1 more source