Results 41 to 50 of about 677,185 (349)

Oral cancer in the UK: to screen or not to screen. [PDF]

open access: yes, 1998
Although oral squamous cell carcinoma accounts for only a small proportion of malignant neoplasms in the UK, oral cancer incidence and mortality rates have been rising in recent years.
Rodrigues, Veena
core  

Oral squamous cell carcinoma of tongue: Histological risk assessment. A pilot study [PDF]

open access: yes, 2019
Background: More than 90% of malignant tumors diagnosed in the oral cavity are Oral Squamous Cell Carcinomas (OSCC) whose preferred location is the tongue.
Cebrián Carretero, José Luis   +4 more
core   +3 more sources

A patient with multiple primary malignant neoplasms with high variant allele frequencies of RB1, TP53, and TERT

open access: yesBiomarker Research
Multiple primary malignant neoplasms are a rare disease with tumors of different histology or morphology arising in various sites. Next-generation sequencing is essential in the etiology, diagnosis, treatment, and surveillance of this disease.
Mingyang Ma   +5 more
semanticscholar   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Expression of E-cadherin and involucrin in leukoplakia and oral cancer: an immunocytochemical and immunohistochemical study

open access: yesBrazilian Oral Research, 2017
To assess the immunocytochemical and immunohistochemical correlation of adhesion (E-cadherin) and cell differentiation (involucrin) molecules in oral leukoplakia and oral squamous cell carcinoma.
Alessandra Dutra da SILVA   +7 more
doaj   +1 more source

Feline vestibular disorders. Part II: diagnostic approach and differential diagnosis. [PDF]

open access: yes, 1999
Results of a neurological examination usually permit localisation of a vestibular disorder to either the central or peripheral parts of the vestibular system. Many different disorders located in the same part of the vestibular system will produce similar
LeCouteur, RA, Vernau, KM
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Advanced Primary Lymphoma of Oral Cavity: Report of a Case [PDF]

open access: yes, 2014
Usually the oral manifestations of NHL are secondary to a more widespread involvement throughout the body, however, it can rarely present as a primary lesion in the oral cavity, having 0.1% - 0.2% prevalence.
Alirezaei, S.   +4 more
core  

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Oral fibrolipoma

open access: yesAutopsy and Case Reports, 2023
Lipoma is a benign mesenchymal tumor of adipocytes.1 It is most common in mid-aged adults with no gender predilection.2 It is uncommon in the oral cavity and represents 1 to 4% of all benign lesions in this area.
Hela Zouaghi   +6 more
doaj  

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