Results 131 to 140 of about 28,224,284 (340)
Locating multiple tumors by moving shape analysis
Mathematical Biosciences, 2013 A methodology to determine the unknown shape of an embedded tumor is proposed. A functional that represents the mismatch between a measured experimental temperature profile, which may be obtained by infrared thermography at skin surface, and the solution of an appropriate boundary problem is defined.
Padra, Claudio, Salva, Natalia Nieves
openaire +3 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Robust Management, Risk and the Ecosystem Approach to Fisheries [PDF]
, 2008 Biodiversity has not been a prominent consideration in conventional fishery management, even though biological concerns and the concept of "sustainability" are long-established in fisheries. This is because traditionally, the focus of management has been
Anthony Charles
core
Small-world behavior in a system of mobile elements
, 2000 We analyze the propagation of activity in a system of mobile automata. A number r L^d of elements move as random walkers on a lattice of dimension d, while with a small probability p they can jump to any empty site in the system. We show that this system
Delgado, Jordi +2 more
core +2 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Standardisation of Provenance Systems in Service Oriented Architectures --- White Paper
, 2006 This White Paper presents provenance in computer systems as a mechanism by which business and e-science can undertake compliance validation and analysis of their past processes.
Ibbotson, John, Moreau, Luc
core
Learning more from crossing levels: Investigating agility at three levels of the organization
, 2018 Scholars have tried to explain how organizations can build agile teams by only looking at one level of analysis. We argue in this short paper that lessons can be learned from organizational science results explaining variance on three different ...
Gren, Lucas
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source