Results 41 to 50 of about 974,805 (252)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Generalized Dystonia and Paroxysmal Dystonic Attacks due to a Novel ATP1A3 Variant

Tremor and Other Hyperkinetic Movements, 2019
Background: Paroxysmal movement disorders are a heterogeneous group of neurological diseases, better understood in recent years thanks to widely available genetic testing.
Carlos Zúñiga-Ramírez, Mirelle Kramis-Hollands, Rodrigo Mercado-Pimentel, Héctor Alberto González-Usigli, Michel Sáenz-Farret, Alberto Soto-Escageda, Alfonso Fasano   +6 more
doaj   +1 more source

Symptomatic treatment of children with anti-NMDAR encephalitis. [PDF]

, 2016
AIM: We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis.
Brilot, F, Dale, R. C., Hong, M, Jones, H, Mohammad, Ss, Nosadini, M, Pillai, Sc, Sharpe, C   +7 more
core   +1 more source

Psychogenic Movement Disorders [PDF]

Continuum, 2013
This review describes the main clinical features of psychogenic (functional) movement disorders and reports recent advances in diagnosis, pathophysiology, and treatment.The terminology and definition of patients with psychogenic movement disorders remain subjects of controversy; the term "functional" has been used more frequently in the literature in ...
MORGANTE, FRANCESCA, Edwards MJ, Espay A.J.   +2 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Brittle Dyskinesia Following STN but not GPi Deep Brain Stimulation

Tremor and Other Hyperkinetic Movements, 2014
Background: The aim was to describe the prevalence and characteristics of difficult to manage dyskinesia associated with subthalamic nucleus (STN) deep brain stimulation (DBS).
Ashok Sriram, Kelly D. Foote, Genko Oyama, Joshua Kwak, Pamela R. Zeilman, Michael S. Okun   +5 more
doaj   +1 more source

Kinect as an access device for people with cerebral palsy: A preliminary study [PDF]

, 2017
Cerebral palsy (CP) describes a group of disorders affecting the development of movement and posture, causingactivity limitation. Access to technology can alleviate some of these limitations.
Cabrera Cabrera, Rafael, García de las Heras, Joaquín, Gómez González, Isabel María, Molina Cantero, Alberto Jesús   +3 more
core  

Systems and methods for physiological signal enhancement and biometric extraction using non-invasive optical sensors [PDF]

, 2018
A system and method for signal processing to remove unwanted noise components including: (i) wavelength-independent motion artifacts such as tissue, bone and skin effects, and (ii) wavelength-dependent motion artifact/noise components such as venous ...
Nourani, Mehrdad, Yousefi, Rasoul
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Radiological markers of CSF α-synuclein aggregation in Parkinson’s disease patients

npj Parkinson's Disease
Alpha-synuclein (αS) aggregation is a widely regarded hallmark of Parkinson’s disease (PD) and can be detected through synuclein amplification assays (SAA).
Amgad Droby, Avital Yoffe-Vasiliev, Daniel Atias, Kyle B. Fraser, Omar S. Mabrouk, Nurit Omer, Anat Bar-Shira, Mali Gana-Weisz, Orly Goldstein, Moran Artzi, Dafna Ben Bashat, Roy N. Alcalay, Avi Orr-Urtreger, Julia C. Shirvan, Jesse M. Cedarbaum, Nir Giladi, Anat Mirelman, Avner Thaler   +17 more
doaj   +1 more source