Identification of the Pathogen <i>Dorcadia ioffi Smit</i> and Evaluation of the Effect of Different Drugs. [PDF]
Li X +7 more
europepmc +1 more source
The ability of an oral combination of afoxolaner, moxidectin and pyrantel to protect dogs from Borrelia burgdorferi infections transmitted by Ixodes scapularis. [PDF]
Prullage J +5 more
europepmc +1 more source
Automated larval motility assays reveal links between eprinomectin treatment failure and drug resistance in Haemonchus contortus. [PDF]
Petermann J +11 more
europepmc +1 more source
Life Stage-Specific Burdens and Impacts of Gastrointestinal Nematodes in Beef Cattle in the United States: A Review of Diagnostics, Impacts on Productivity, and Immune Response. [PDF]
Laubinger BL, Harvey KM, Jumper WI.
europepmc +1 more source
Moxidectin: an oral treatment for human onchocerciasis [PDF]
Moxidectin is a milbemycin endectocide recently approved for the treatment of human onchocerciasis. Onchocerciasis, earmarked for elimination of transmission, is a filarial infection endemic in Africa, Yemen, and the Amazonian focus straddling Venezuela and Brazil.
Philip Milton +2 more
exaly +5 more sources
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Moxidectin induces autophagy arrest in colorectal cancer
Medical Oncology, 2022Colorectal cancer (CRC) is a cancer with a high morbidity and mortality worldwide. Hence, developing new therapeutic drugs for CRC is very important. Moxidectin (MOX) has shown good anti-glioblastoma effect both in vitro and in vivo. This study aimed to elucidate the anti-CRC effect of MOX and its potential mechanism by investigating the influence of ...
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Moxidectin and the avermectins: Consanguinity but not identity
The avermectins and milbemycins contain a common macrocyclic lactone (ML) ring, but are fermentation products of different organisms. The principal structural difference is that avermectins have sugar groups at C13 of the macrocyclic ring, whereas the milbemycins are protonated at C13.
Roger K Prichard
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