Results 41 to 50 of about 2,380 (175)

The efficacy of antiparasitic drug in the form of spray based on Flumethrin, Moxidectin and Pyriproxyfen against canine acarosis

Российский паразитологический журнал, 2023
The purpose of the research is to study the efficacy of the drug in the form of spray based on Fipronil, Moxidectin and Pyriproxyfen against canine acarosis.Materials and methods.
M. V. Arisov, S. B. Devyatyarova
doaj   +1 more source

Pharmacokinetics of Moxidectin in Bare‐Nosed Wombats (Vombatus ursinus) After Intravenous, Sub‐Cutaneous and Transdermal Administration

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The anti‐parasitic drug moxidectin is a frontline treatment for sarcoptic mange in bare‐nosed wombats (Vombatus ursinus), a disease causing significant animal welfare issues and instances of local population declines. Despite widespread usage, knowledge of species‐specific pharmacokinetics of moxidectin in bare‐nosed wombats is still limited ...
E. K. Stott, L. F. Skerratt, T. Whittem, M. Leeming, K. Pillay, G. S. Doran, B. Gardner, M. Lynch, M. Klein, P. Holz, T. Chen, J. Hufschmid, A. P. Woodward   +12 more
wiley   +1 more source

Synthesis and Antiparasitic Activities of New Organometallic Derivatives of the Benzimidazole Anthelmintic Drugs

ChemBioChem, Volume 27, Issue 15, 14 August 2026.
Organometallic derivatization of existing drugs is a common strategy to look for new drug candidates. This work describes the derivatization of the benzimidazole anthelmintic scaffold, from the synthesis of the organometallic derivatives to the evaluation of their biological properties. It highlights a broad range of antiparasitic activities and leaves
Corentin Ludwig, Aya C. Taki, Joseph J. Byrne, Pierre Mesdom, Olivier Blacque, Cécile Häberli, Trix Zumkehr, Gonzalo Scalese, Leticia Pérez‐Díaz, Dinorah Gambino, Britta Lundström‐Stadelmann, Jennifer Keiser, Robin B. Gasser, Kevin Cariou, Gilles Gasser   +14 more
wiley   +1 more source

Eficacy of ivermectin, moxidectin and febendazole in equine in Brazil

Veterinary Parasitology: Regional Studies and Reports, 2020
The objectives of the present study were to evaluate the efficacy of three anthelmintic drugs, i.e. fenbendazole, ivermectin and moxidectin; to determine the genera and species of the most abundant strongyles; and to investigate parasite control measures used in herds of horses in the western region of the state of São Paulo, Brazil.
Vera, João Henrique Silva, Fachiolli, Daniele Floriano, Ramires, Lívia Magosso, de Lima Saes, Isabela, Yamada, Paulo Henrique, Gonçalves, Juliana Alencar, de Oliveira, Kátia, do Amarante, Alessandro Francisco Talamini, de Soutello, Ricardo Velludo Gomes   +8 more
openaire   +3 more sources

Efficacy of a combination of 10% imidacloprid and 1% moxidectin against Caparinia tripilis in African pygmy hedgehog (Atelerix albiventris)

Parasites & Vectors, 2012
Background The efficacy and safety of a combination formulation of 10% imidacloprid + 1.0% moxidectin spot-on (Advocate® for Cats, Bayer Animal Health GmbH, Leverkusen, Germany) was tested in 40 African pygmy hedgehogs (Atelerix albiventris) naturally ...
Kim Kyu-Rim, Ahn Kyu-Sung, Oh Dae-Sung, Shin Sung-Shik   +3 more
doaj   +1 more source

A Systematic Review of Published Physiologically Based Pharmacokinetic Models for Drug Excretion Into Human Breastmilk: Knowledge Gaps and Opportunities to Optimize Reporting and Modeling Practices

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
ABSTRACT Physiologically based pharmacokinetic (PBPK) modeling is increasingly used to predict infant exposure to medications via breast milk. Existing guidance on reporting of PBPK modeling analyses is unstructured and nonbinding to researchers. We evaluated reporting practices and modeling approaches in published PBPK modeling studies.
Joshua Kiptoo, Davies Otieno, Kenta Yoshida, Neel Deferm, Aida Nakayiwa Kawuma, Francis Williams Ojara, Adeniyi Olagunju, Jackson K. Mukonzo, Catriona Waitt   +8 more
wiley   +1 more source

Effectiveness of the Combination of Imidacloprid/ Moxidectin/ Praziquantel and Moxidectin/ Praziquantel Applied Topically in Dogs with Endoparasites and Ectoparasites

The Open Parasitology Journal, 2023
Background: Topically applied antiparasitic drugs used in dogs have evolved in terms of active ingredients, but progress has also been made through the development of drugs that control both ectoparasites and enteroparasites (nematodes and cestodes).
Camilo R. Núñez, Roger I. Rodríguez-Vivas, Ariadna F. Ortega, Rafael H. Cárdenas   +3 more
openaire   +1 more source

International Survey on Screening and Management of Strongyloidiasis in Solid Organ Transplant Patients

Transplant Infectious Disease, Volume 28, Issue 4, July/August 2026.
This international cross‐sectional survey of healthcare workers caring for solid organ transplant patients identified knowledge gaps regarding Strongyloides transmission and mortality, particularly among non‐infectious disease providers. Screening strategies varied geographically, with universal screening more common in endemic areas and targeted ...
Jacques Simkins, Akshatha Ravindra, Cameron R. Wolfe, Alessandra Mularoni, Monica Slavin, Ines Ushiro‐Lumb, John W. Baddley, Jonathan Hand, Stephanie Pouch, Maricar Malinis, Maristela P. Freire, Marcelo Radisic, Matthew B. Roberts, Ban Hock Tan, Siriorn Watcharananan, Wanessa T. Clemente   +15 more
wiley   +1 more source

Effect of multidrug resistance modulators on the activity of ivermectin and moxidectin against selected strains of Haemonchus contortus infective larvae

Pesquisa Veterinária Brasileira, 2001
Nematode parasites have shown resistance to the anthelmintics, ivermectin and moxidectin, and there is evidence that the over-expression of parasite P-glycoprotein (P-gp) may account, at least in part, for resistance to ivermectin.
Molento Marcelo B., Prichard Roger K.
doaj  

A Large Impact of Obesity on the Disposition of Ivermectin, Moxidectin and Eprinomectin in a Canine Model: Relevance for COVID-19 Patients

Frontiers in Pharmacology, 2021
Ivermectin (IVM) and moxidectin (MOX) are used extensively as parasiticides in veterinary medicine. Based on in vitro data, IVM has recently been proposed for the prevention and treatment of COVID-19 infection, a condition for which obesity is a major ...
Alain Bousquet-Mélou, Anne Lespine, Jean-François Sutra, Isabelle Bargues, Pierre-Louis Toutain, Pierre-Louis Toutain   +5 more
doaj   +1 more source