Results 21 to 30 of about 2,380 (175)

Field effectiveness and safety of fluralaner plus moxidectin (Bravecto® Plus) against ticks and fleas: a European randomized, blinded, multicenter field study in naturally-infested client-owned cats

Parasites & Vectors, 2018
Background A spot-on formulation containing fluralaner (280 mg/ml) plus moxidectin (14 mg/ml) (Bravecto® Plus) has been developed to provide broad spectrum parasite protection for cats. The effectiveness and safety of this product against ticks and fleas
Nadja Rohdich, Eva Zschiesche, Oliver Wolf, Wolfgang Loehlein, Thierry Pobel, Maria José Gil, Rainer K. A. Roepke   +6 more
doaj   +1 more source

Praziquantel and Moxidectin pharmacokinetics in dogs after Helmimax administration

Российский паразитологический журнал, 2023
The purpose of the research is to study Praziquantel and Moxidectin pharmacokinetics in dogs after Helmimax administration.Materials and methods. Helmimax pharmacokinetics was studied on 8 adult male dogs of different breeds aged 2 to 5 years and ...
A. A. Smirnov, V. O. Bondarenko, N. I. Soboleva, O. A. Makhlis, A. S. Chagin   +4 more
doaj   +1 more source

The potential impact of moxidectin on onchocerciasis elimination in Africa: an economic evaluation based on the Phase II clinical trial data

Parasites & Vectors, 2015
Background Spurred by success in several foci, onchocerciasis control policy in Africa has shifted from morbidity control to elimination of infection. Clinical trials have demonstrated that moxidectin is substantially more efficacious than ivermectin in ...
Hugo C Turner, Martin Walker, Simon K Attah, Nicholas O Opoku, Kwablah Awadzi, Annette C Kuesel, María-Gloria Basáñez   +6 more
doaj   +1 more source

Comparative studies of early season moxidectin treatment and conventional ivermectin/ benzimidazole treatments in the control of cyathostomes in horses

Veterinární Medicína, 2003
Moxidectin administered in January or February at a single dose was tested for efficacy in horses on two farms for 12 and 11 months, respectively. Horses were infected with cyathostomes naturally in the previous grazing period. Forty horses of farm 1 and
I. Langrová, I. Jankovská, M. Borovský   +2 more
doaj   +1 more source

Moxidectin and the avermectins: Consanguinity but not identity

International Journal for Parasitology: Drugs and Drug Resistance, 2012
The avermectins and milbemycins contain a common macrocyclic lactone (ML) ring, but are fermentation products of different organisms. The principal structural difference is that avermectins have sugar groups at C13 of the macrocyclic ring, whereas the milbemycins are protonated at C13.
Prichard, Roger, Menez-Berlioz, Cécile, Lespine, Anne   +2 more
openaire   +4 more sources

A randomized, single-ascending-dose, ivermectin-controlled, double-blind study of moxidectin in Onchocerca volvulus infection.

PLoS Neglected Tropical Diseases, 2014
BackgroundControl of onchocerciasis as a public health problem in Africa relies on annual mass ivermectin distribution. New tools are needed to achieve elimination of infection.
Kwablah Awadzi, Nicholas O Opoku, Simon K Attah, Janis Lazdins-Helds, Annette C Kuesel   +4 more
doaj   +1 more source

Efficacy of fluralaner plus moxidectin (Bravecto® Plus spot-on solution for cats) against Otodectes cynotis infestations in cats

Parasites & Vectors, 2018
Background The efficacy of the fixed combination of fluralaner plus moxidectin for the treatment of Otodectes cynotis infestations was evaluated in cats after topical application. Methods Sixteen cats experimentally infested with O.
Janina Taenzler, Christa de Vos, Rainer K. A. Roepke, Anja R. Heckeroth   +3 more
doaj   +1 more source

Effect of Moxidectin on Bed Bug Feeding, Development, Fecundity, and Survivorship

Insects, 2017
The common bed bug, Cimex lectularius L. (Hemiptera: Cimicidae), is a blood-feeding ectoparasite which experienced world-wide resurgence during recent decades.
Chen Zha, Changlu Wang, Johnathan Michael Sheele   +2 more
doaj   +1 more source

The Use of Sarmazenil in the Treatment of a Moxidectin Intoxication in a Foal [PDF]

Journal of Veterinary Internal Medicine, 2005
Abstract A13-day-old Arabian Thoroughbred filly weighing 40 kg (88 1b) was presented to the University of Zurich Equine Clinic with a history of depression after deworming with moxidectin at a dose of 2 mg/kg (recommended dose 0.4 mg/kg body weight)a the day before admission.
Müller, Jessika-M V, Feige, Karsten, Kästner, Sabine Beate Rita, Naegeli, Hanspeter   +3 more
openaire   +3 more sources

Safety of topical administration of fluralaner plus moxidectin concurrently with praziquantel in cats

Parasites & Vectors, 2018
Background Fluralaner provides efficacy against feline ectoparasites following topical administration. Moxidectin is routinely used to treat gastrointestinal nematode infections and prevent heartworm disease caused by Dirofilaria immitis. Praziquantel is
Feli M. Walther, Petr Fisara, Rainer K. A. Roepke   +2 more
doaj   +1 more source