Results 21 to 30 of about 3,761 (208)

Moxidectin as an Endectocide in Reindeer [PDF]

Acta Veterinaria Scandinavica, 1998
During the winter 1991-92, 42 reindeer hinds of the Kaamanen Experimental Reindeer Herd in Finnish Lapland, naturally infected with various parasites, were allocated to 3 groups. One group was an untreated control group and the other 2 groups received either moxidectin or ivermectin at a dose of 200 micrograms kg-1 subcutaneously.
A, Oksanen, M, Nieminen
openaire   +2 more sources

Functional Characterization of the Cat and Dog Wild-Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany. [PDF]

J Vet Pharmacol Ther
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Siegl L, Bethäuser M, Nürnberger D, Oswald S, Moritz A, Hamann M, Geyer J.   +6 more
europepmc   +2 more sources

Selamectin is the avermectin with the best potential for Buruli ulcer treatment [PDF]

, 2015
A comprehensive analysis was done to evaluate the potential use of anti-parasitic macrocyclic lactones (including avermectins and milbemycins) for Buruli ulcer (BU) therapy.
Gerd Pluschke, Scherr, Nicole, Thompson, Charles J., Charles J Thompson, Nicole Scherr, Ramón-García, Santiago, Santiago Ramón-García, Pluschke, Gerd   +7 more
core   +1 more source

Pharmacoeconomic Analysis of Heartworm Preventive Compliance and Revenue in Veterinary Practices in the United States

Frontiers in Veterinary Science, 2021
Background: Heartworm disease (HWD) is a potentially fatal condition caused by the nematode Dirofilaria immitis. It is endemic in North America, and the American Heartworm Society recommends that owned dogs be on a Food and Drug Administration-approved ...
Kennedy Mwacalimba, Deborah Amodie, Lisa Swisher, Marina Moldavchuk, Christopher Brennan, Claire Walther, Kelly Bowman   +6 more
doaj   +1 more source

Ivermectin and moxidectin against soil-transmitted helminth infections

, 2023
Ivermectin and moxidectin, two macrocyclic lactones, are potent antiparasitic drugs currently registered and mainly used against filarial diseases; however, their potential value for improved soil-transmitted helminth (STH) control has been acknowledged.
Hofmann, D., Keiser, J., Hürlimann, E.
core   +1 more source

Preventive efficacy of four or six monthly oral doses of 24 µg/kg moxidectin compared to six monthly doses of Heartgard® Plus or Interceptor® Plus against macrocyclic lactone-resistant heartworm (Dirofilaria immitis) strains in dogs

Parasites & Vectors, 2020
Background Recent reports indicated that increasing the monthly oral dosage and the number of consecutive monthly doses of moxidectin improved the efficacy against macrocyclic lactone (ML)-resistant Dirofilaria immitis.
Kristina Kryda, Susan Holzmer, William R. Everett, John W. McCall, Sean P. Mahabir, Tom L. McTier, Steven J. Maeder   +6 more
doaj   +1 more source

The potential impact of moxidectin on onchocerciasis elimination in Africa: an economic evaluation based on the Phase II clinical trial data

Parasites & Vectors, 2015
Background Spurred by success in several foci, onchocerciasis control policy in Africa has shifted from morbidity control to elimination of infection. Clinical trials have demonstrated that moxidectin is substantially more efficacious than ivermectin in ...
Hugo C Turner, Martin Walker, Simon K Attah, Nicholas O Opoku, Kwablah Awadzi, Annette C Kuesel, María-Gloria Basáñez   +6 more
doaj   +1 more source

Comparative studies of early season moxidectin treatment and conventional ivermectin/ benzimidazole treatments in the control of cyathostomes in horses

Veterinární Medicína, 2003
Moxidectin administered in January or February at a single dose was tested for efficacy in horses on two farms for 12 and 11 months, respectively. Horses were infected with cyathostomes naturally in the previous grazing period. Forty horses of farm 1 and
I. Langrová, I. Jankovská, M. Borovský   +2 more
doaj   +1 more source

Field effectiveness and safety of fluralaner plus moxidectin (Bravecto® Plus) against ticks and fleas: a European randomized, blinded, multicenter field study in naturally-infested client-owned cats

Parasites & Vectors, 2018
Background A spot-on formulation containing fluralaner (280 mg/ml) plus moxidectin (14 mg/ml) (Bravecto® Plus) has been developed to provide broad spectrum parasite protection for cats. The effectiveness and safety of this product against ticks and fleas
Nadja Rohdich, Eva Zschiesche, Oliver Wolf, Wolfgang Loehlein, Thierry Pobel, Maria José Gil, Rainer K. A. Roepke   +6 more
doaj   +1 more source

Moxidectin dose and severity of infection by cohort.

, 2022
Moxidectin dose and severity of infection by cohort.
Nicholas Opoku (3542828), Annette C. Kuesel (12295325), Mark Sullivan (459776), Beesan Tan (1637749), Janis Lazdins-Helds (589135), Simon K. Attah (10537221), Kwablah Awadzi (169148), Victoria Ryg-Cornejo (455804), Lawrence Fleckenstein (232882), Craig Rayner (272749)   +9 more
core   +1 more source