Results 11 to 20 of about 3,761 (208)

Solvatomorphism of Moxidectin [PDF]

Molecules, 2021
The solvatomorphism of the anthelmintic drug moxidectin is investigated, and a new solvatomorph with nitromethane is reported. Moreover, the hitherto unknown crystal structures of the solvatomorphs with ethanol and 2-propanol are reported and discussed.
Toni Grell, Mauro Barbero, Franco Pattarino, Giovanni Battista Giovenzana, Valentina Colombo   +4 more
openaire   +6 more sources

Efficacy and Safety of Moxidectin, Synriam, Synriam-Praziquantel versus Praziquantel against Schistosoma haematobium and S. mansoni Infections: A Randomized, Exploratory Phase 2 Trial. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Schistosomiasis affects millions of people, yet treatment options are limited. The antimalarial Synriam (piperaquine 150 mg/arterolane 750 mg) and the anthelminthic moxidectin revealed promising antischistosomal properties in preclinical or ...
Beatrice Barda, Jean T Coulibaly, Maxim Puchkov, Jörg Huwyler, Jan Hattendorf, Jennifer Keiser   +5 more
doaj   +3 more sources

Efficacy of oral moxidectin against susceptible and resistant isolates of Dirofilaria immitis in dogs

Parasites & Vectors, 2017
Background Monthly topical and sustained-release injectable formulations of moxidectin are currently marketed; however, an oral formulation, while approved at a dose of 3 μg/kg, is not currently marketed in the United States.
Tom L. McTier, Robert H. Six, Aleah Pullins, Sara Chapin, John W. McCall, Douglas Rugg, Steven J. Maeder, Debra J. Woods   +7 more
doaj   +2 more sources

Efficacy of imidacloprid + moxidectin and selamectin topical solutions against the KS1 Ctenocephalides felis flea strain infesting cats [PDF]

Parasites & Vectors, 2011
Background Two studies were conducted to evaluate and compare the efficacy of imidacloprid + moxidectin and selamectin topical solutions against the KS1 flea strain infesting cats.
Dryden Michael W, Payne Patricia A, Smith Vicki, Hostetler Joe   +3 more
doaj   +2 more sources

Moxidectin-resistant nematodes in cattle in Brazil

Veterinary Parasitology, 2009
The frequent use of anthelmintics in cattle has contributed to the emergence of gastrointestinal nematode populations resistant to the drugs available in the market. This study aimed to evaluate moxidectin efficacy in a property with suspected presence of Oesophagostomum spp. resistant to such anthelmintic.
Condi, G. K., Soutello, R. G. V., Amarante, Alessandro Francisco Talamini do   +2 more
openaire   +4 more sources

A randomized, single-ascending-dose, ivermectin-controlled, double-blind study of moxidectin in Onchocerca volvulus infection.

PLoS Neglected Tropical Diseases, 2014
BackgroundControl of onchocerciasis as a public health problem in Africa relies on annual mass ivermectin distribution. New tools are needed to achieve elimination of infection.
Kwablah Awadzi, Nicholas O Opoku, Simon K Attah, Janis Lazdins-Helds, Annette C Kuesel   +4 more
doaj   +2 more sources

Praziquantel and Moxidectin pharmacokinetics in dogs after Helmimax administration

Российский паразитологический журнал, 2023
The purpose of the research is to study Praziquantel and Moxidectin pharmacokinetics in dogs after Helmimax administration.Materials and methods. Helmimax pharmacokinetics was studied on 8 adult male dogs of different breeds aged 2 to 5 years and ...
A. A. Smirnov, V. O. Bondarenko, N. I. Soboleva, O. A. Makhlis, A. S. Chagin   +4 more
doaj   +3 more sources

Effect of Moxidectin on Bed Bug Feeding, Development, Fecundity, and Survivorship

Insects, 2017
The common bed bug, Cimex lectularius L. (Hemiptera: Cimicidae), is a blood-feeding ectoparasite which experienced world-wide resurgence during recent decades.
Chen Zha, Changlu Wang, Johnathan Michael Sheele   +2 more
doaj   +2 more sources

Safety of topical administration of fluralaner plus moxidectin concurrently with praziquantel in cats

Parasites & Vectors, 2018
Background Fluralaner provides efficacy against feline ectoparasites following topical administration. Moxidectin is routinely used to treat gastrointestinal nematode infections and prevent heartworm disease caused by Dirofilaria immitis. Praziquantel is
Feli M. Walther, Petr Fisara, Rainer K. A. Roepke   +2 more
doaj   +2 more sources

Trends in Veterinary Drug Residues in US Cattle: Analysing USDA Sampling Data. [PDF]

Vet Med Sci
National US residue monitoring data (2021–2023) were analysed to characterise veterinary drug residue detections in cattle. Detection patterns varied by cattle type, with dairy cows accounting for the highest number of detections and a consistent group of commonly used drugs responsible for most violative and non‐violative findings.
Alwahaimed AS, Eifert J.
europepmc   +2 more sources