Results 61 to 70 of about 4,217 (163)

Dose-dependent in vivo effects of formulated moxidectin on seedling emergence of temperate grassland species [PDF]

, 2023
Sheep function as effective endozoochorous seed vectors in grasslands. Recent laboratory-based studies showed that this important function can be impaired by macrocyclic lactone anthelmintics, which are used to control parasites and enter into the ...
Laber, Lars, Anabell Jandowsky, Rolf-Alexander Düring, Düring, Rolf-Alexander, Jandowsky, Anabell, Frölich, Kai, Eichberg, Carsten, Andre P. Heinrich, Heinrich, Andre P, Lars Laber, Tobias W. Donath, Kai Frölich, Donath, Tobias, Carsten Eichberg   +13 more
core   +1 more source

A Large Impact of Obesity on the Disposition of Ivermectin, Moxidectin and Eprinomectin in a Canine Model: Relevance for COVID-19 Patients

Frontiers in Pharmacology, 2021
Ivermectin (IVM) and moxidectin (MOX) are used extensively as parasiticides in veterinary medicine. Based on in vitro data, IVM has recently been proposed for the prevention and treatment of COVID-19 infection, a condition for which obesity is a major ...
Alain Bousquet-Mélou, Anne Lespine, Jean-François Sutra, Isabelle Bargues, Pierre-Louis Toutain, Pierre-Louis Toutain   +5 more
doaj   +1 more source

Proliferative Sparganosis Due to Spirometra mansoni in a Dog: A Detailed Diagnostic Picture

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Innumerable small oval cystic structures were identified in the peritoneal cavity of a young dog presenting with abdominal distension and weight gain. A combination of diagnostics confirmed these structures as Spirometra mansoni plerocercoids and established a diagnosis of proliferative sparganosis.
Stephanie Middlemast, Nicholas Lim, Charles G. Gauci, Abdul Jabbar   +3 more
wiley   +1 more source

Synthesis and Antiparasitic Activities of New Organometallic Derivatives of the Benzimidazole Anthelmintic Drugs

ChemBioChem, Volume 27, Issue 15, 14 August 2026.
Organometallic derivatization of existing drugs is a common strategy to look for new drug candidates. This work describes the derivatization of the benzimidazole anthelmintic scaffold, from the synthesis of the organometallic derivatives to the evaluation of their biological properties. It highlights a broad range of antiparasitic activities and leaves
Corentin Ludwig, Aya C. Taki, Joseph J. Byrne, Pierre Mesdom, Olivier Blacque, Cécile Häberli, Trix Zumkehr, Gonzalo Scalese, Leticia Pérez‐Díaz, Dinorah Gambino, Britta Lundström‐Stadelmann, Jennifer Keiser, Robin B. Gasser, Kevin Cariou, Gilles Gasser   +14 more
wiley   +1 more source

A comparative kinetic study of doramectin and moxidectin in zebu Gobra cattle (Bos indicus)

, 2008
International audienceThe plasma kinetics of doramectin and moxidectin were evaluated in zebu Gobra under field conditions after subcutaneous administration of 0.2 mg kg−1 of commercially available formulations for cattle.
Panguy, L.J., Bengone-Ndong, T., Mvouaka, S.K., Alvinerie, Roger, Kane, Y., Loudy-Moukédé, W.A.   +5 more
core   +1 more source

Tolerability Profile of Antiparasitic Drug «Gelmintal Mini Syrup» Administered as a Single and Repeated Dose to Target Animal Species

Российский паразитологический журнал, 2020
The purpose of the research is studying the tolerability profile of drug» Gelmintal Mini Syrup» based on toltrazuril and moxidectin in therapeutic and increased doses administered once and repeatedly to target animal species. Materials and methods.
G. B. Arisova, M. V. Arisov, I. A. Stepanova, V. V. Khristenko   +3 more
doaj   +1 more source

A Systematic Review of Published Physiologically Based Pharmacokinetic Models for Drug Excretion Into Human Breastmilk: Knowledge Gaps and Opportunities to Optimize Reporting and Modeling Practices

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
ABSTRACT Physiologically based pharmacokinetic (PBPK) modeling is increasingly used to predict infant exposure to medications via breast milk. Existing guidance on reporting of PBPK modeling analyses is unstructured and nonbinding to researchers. We evaluated reporting practices and modeling approaches in published PBPK modeling studies.
Joshua Kiptoo, Davies Otieno, Kenta Yoshida, Neel Deferm, Aida Nakayiwa Kawuma, Francis Williams Ojara, Adeniyi Olagunju, Jackson K. Mukonzo, Catriona Waitt   +8 more
wiley   +1 more source

Pharmaco-toxicological Assessment of Antiparasitic Drug for Dogs and Cats "Gelmintal Mini Syrup"

Российский паразитологический журнал, 2020
The purpose of the research is conducting pharmaco-toxicological assessment of Gelmintal Mini Syrup based on a combination of moxidectin and toltrazuril. Materials and methods. The study was carried out on 64 white male rats and 40 white mice.
G. B. Arisova, M. V. Arisov, I. A. Stepanova, V. V. Khristenko   +3 more
doaj   +1 more source

International Survey on Screening and Management of Strongyloidiasis in Solid Organ Transplant Patients

Transplant Infectious Disease, Volume 28, Issue 4, July/August 2026.
This international cross‐sectional survey of healthcare workers caring for solid organ transplant patients identified knowledge gaps regarding Strongyloides transmission and mortality, particularly among non‐infectious disease providers. Screening strategies varied geographically, with universal screening more common in endemic areas and targeted ...
Jacques Simkins, Akshatha Ravindra, Cameron R. Wolfe, Alessandra Mularoni, Monica Slavin, Ines Ushiro‐Lumb, John W. Baddley, Jonathan Hand, Stephanie Pouch, Maricar Malinis, Maristela P. Freire, Marcelo Radisic, Matthew B. Roberts, Ban Hock Tan, Siriorn Watcharananan, Wanessa T. Clemente   +15 more
wiley   +1 more source

Parasite management practices used by owners of Australian Pony Club horses and the factors influencing their decision‐making processes

Australian Veterinary Journal, Volume 104, Issue 5, Page 305-310, May 2026.
There is a lack of information on horse parasite management practices currently used by individual horse owners in Australia. A voluntary, anonymous online survey was developed for and distributed by Pony Club Australia to its members seeking information on horse population; housing; paddock, manure and parasite management; and owner attitudes.
W Nixon, P Buckley, R Butler
wiley   +1 more source