Results 71 to 80 of about 9,249 (288)

Inefficacy of ivermectin and moxidectin treatments against Dictyocaulus viviparus in dairy calves.

The Veterinary Record
BACKGROUND The bovine lungworm Dictyocaulus viviparus negatively impacts bovine health and leads to substantial economic losses. Lungworm infections can be difficult to manage due to the unpredictable and severe nature of clinical outbreaks.
Paul Campbell, Andrew Forbes, J. McIntyre, Taylor Bartoschek, Kayleigh Devine, Kerry O’Neill, R. Laing, Kathryn Ellis   +7 more
semanticscholar   +1 more source

Safety and Short-term Efficacy of a Single Dose of 2 mg Moxidectin in Loa loa–Infected Individuals: A Double-Blind, Randomized Ivermectin-Controlled Trial With Ascending Microfilarial Densities

Open Forum Infectious Diseases
Background In 2018, the US Food and Drug Administration approved the macrocylic lactone moxidectin (MOX) at 8 mg dosage for onchocerciasis treatment in individuals aged ≥12 years.
G. S. Wafeu, Tristan M. Lepage, Jérémy T. Campillo, Arnauld Efon-Ekangouo, H. Nana-Djeunga, Narcisse Nzune-Toche, A. Domché, Laurentine Sumo, G. Njitchouang, M. A. Tsasse, J. Bopda, Yves Aubin Balog, Yannick Niamsi-Emalio, Stève Mbickmen-Tchana, Gervais Kamga Talla, Yannick Sédrick Nguedia Kana, Félicité Diane Maga Messina, S. Pion, A. Kuesel, J. Kamgno, M. Boussinesq, C. Chesnais   +21 more
semanticscholar   +1 more source

Efficacy of a formulation of sarolaner/moxidectin/pyrantel (Simparica Trio®) for the prevention of Thelazia callipaeda canine eyeworm infection

Parasites & Vectors, 2022
Background For a long time known as the oriental eyeworm, Thelazia callipaeda is a zoonotic nematode that infects the eyes of a wide range of vertebrate hosts including dogs, cats, wildlife carnivores, lagomorphs, and humans.
M. A. Bezerra-Santos, J. Mendoza-Roldan, G. Sgroi, R. Lia, Giulia Venegoni, F. Solari Basano, Roose Nele, S. Mahabir, Stasia Borowski, T. Geurden, D. Otranto   +10 more
semanticscholar   +1 more source

How can onchocerciasis elimination in Africa be accelerated? Modelling the impact of increased ivermectin treatment frequency and complementary vector control [PDF]

, 2017
Background: Great strides have been made toward onchocerciasis elimination by mass drug administration (MDA) of ivermectin. Focusing on MDA-eligible areas, we investigated where the elimination goal can be achieved by 2025 by continuation of current ...
Afework H Tekle, Alley, Annette C Kuesel, Basáñez, Basáñez, Basáñez, Bottomley, Boussinesq, Coffeng, Coffeng, Coffeng, Colebunders, Daniel A Boakye, Dyson, Filipe, GBD 2016 Disease and Injury Incidence and Prevalence Collaborators, Grace Fobi, Habbema, Honorat G M Zouré, Kaiser, Kamgno, Katabarwa, Kim, Little, Lont, Maria-Gloria Basáñez, Martin Walker, Matthews, Michel Boussinesq, Opoku, Plaisier, Plaisier, Plaisier, Sake J de Vlas, Samuel Wanji, Stolk, Stolk, Suzanne Verver, Tekle, Tekle, Traore, Turner, Turner, Turner, Turner, Walker, Walker, Walker, Walker, Wilma A Stolk, World Health Organization, World Health Organization, World Health Organization/African Programme for Onchocerciasis Control, World Health Organization/African Programme for Onchocerciasis Control, World Health Organization/African Programme for Onchocerciasis Control, World Health Organization/African Programme for Onchocerciasis Control, World Health Organization/African Programme for Onchocerciasis Control, Young Eun Kim, Zouré, Zouré   +59 more
core   +5 more sources

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl, Mies Bethäuser, Daniela Nürnberger, Stefan Oswald, Andreas Moritz, Melanie Hamann, Joachim Geyer   +6 more
wiley   +1 more source

Analysis of Strongyle Egg Shedding Consistency in Horses and Factors That Affect It [PDF]

, 2018
Strongyle egg shedding consistency in horses and factors affecting consistency were investigated. Fecal samples were collected from 26 equine populations over one grazing season.
Hodgkinson, Jane E., Lester, H.E., Matthews, Jacqueline B., Morgan, E.R.   +3 more
core   +1 more source

Recurrent haemorrhage, due to vitamin K‐dependent coagulopathy, as the primary presenting complaint in a dog with naturally occurring hypoadrenocorticism

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 5‐year‐old male neutered standard poodle, presented with recurrent gingival margin haemorrhage and associated prolongations in prothrombin time and activated partial thromboplastin time, with repeatable demonstration of clinical (bleeding) and laboratory (prothrombin time, activated partial thromboplastin time) resolution with, and relapse ...
Jenny Reeve, Aiden Pang
wiley   +1 more source

An Updated Economic Assessment of Moxidectin Treatment Strategies for Onchocerciasis Elimination

Clinical Infectious Diseases
Background Concerns that annual mass administration of ivermectin, the predominant strategy for onchocerciasis control and elimination, may not lead to elimination of parasite transmission (EoT) in all endemic areas have increased interest in alternative
Hugo C Turner, K. Kura, Barbara Roth, A. Kuesel, S. Kinrade, M. Basáñez   +5 more
semanticscholar   +1 more source

Canine Angiostrongylus vasorum [PDF]

, 2011
The French heartworm Angiostrougylus vasorum is a parasitic nematode that lives in the pulmonary vessels and the heart of canids. Transmission occurs through ingestion of infected intermediate hosts, such as snails and slugs. There are increasing reports
Binst, Dominique, Claerebout, Edwin, Daminet, Sylvie, Moeremans, Ilse, Van de Maele, Isabel   +4 more
core  

Challenges and opportunities in mitigating sarcoptic mange in wild South American camelids

The Journal of Wildlife Management, Volume 90, Issue 1, January 2026.
Wild South American camelids—vicuña and guanaco—face threats from sarcoptic mange, a contagious skin disease linked to severe population declines. Despite its impact, major gaps remain in understanding disease dynamics. This review summarizes current knowledge, identifies key data and management gaps, and outlines urgent actions for effective ...
Alynn M. Martin, Emiliana Isasi‐Catalá, Marília Salgado‐Caxito, Ana Gallegos, Leonardo Hostos‐Olivera, Paulo Colchao‐Claux, Steve Smith, L. Fabian Beltran‐Saavedra, Catherine Dougnac, Camila Germana, Mariana Montoya, Scott Carver, Paul C. Cross, Christian Walzer   +13 more
wiley   +1 more source