Results 91 to 100 of about 49,999 (227)
British Journal of Haematology, EarlyView.Summary Genomic technologies including next‐generation sequencing (NGS) and arrays for cytogenetic anomalies are now standard of care in England for the diagnostic evaluation of patients with suspected haematological malignancies. Challenges remain in the management of potential germline findings as a result of NGS panels and copy number variant ...
B. Speight +12 more
wiley +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Background Polycythemia vera (PV) and essential thrombocythemia (ET) are associated with a well‐recognized increased risk of thrombotic events, bleeding, and all‐cause mortality, but the frequency of these outcomes during treatment has rarely been assessed in large cohorts.
Anneli Enblom Larsson +5 more
wiley +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Background Individuals with polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) face transformation risks to acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). While older age is linked to increased risk, it remains unclear whether risk increases with age or with disease duration.
Nurgul Batyrbekova +5 more
wiley +1 more source
Sučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2014 В статті розглянуті характеристики транспортних мереж і основні вимоги до їх побудови. Проаналізована технологія мультипротокольної комутації по міткам, її архітектура, наведені основні визначення та терміни даної технології.
Mykola M. Fomin, Inna V. Zhytnyk
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The FEBS Journal, EarlyView.Iduronate 2‐sulfatase (IDS; purple) is expressed as a precursor protein that goes through multiple steps of maturation, modification, and trafficking to become an active lysosomal enzyme that degrades glycosaminoglycans. Our study shows that the transmembrane ubiquitin ligases RNF13 (orange) and RNF167 (pink) heterodimerize, affecting IDS intracellular
Valérie C. Cabana +4 more
wiley +1 more source
Haemophilia, EarlyView.ABSTRACT Introduction The National Bleeding Disorder Foundation (NBDF) Medical and Scientific Advisory Council (MASAC) was formed in 1954 and issues recommendations and advisories pertinent to the bleeding disorders community. MASAC is comprised of > 25 rotating members from different medical disciplines and lived experience experts.
Glaivy Batsuli +15 more
wiley +1 more source
Design and Optimization of Metropolitan Area Networks using Multi-Protocol Label Switching
Majlesi Journal of Electrical EngineeringLooking in to the modern technology, we see new inventions and innovations which are unique. As an example, over the past years, new technology has been created in computer networks of which metropolitan area network (MAN) has had a noticeable advance in
Alireza Emamjomeh +2 more
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Modular Reinforcement Learning for Multi-Market Portfolio Optimization
InformationMost reinforcement learning (RL) methods for portfolio optimization remain limited to single markets and a single algorithmic paradigm, which restricts their adaptability to regime shifts and heterogeneous conditions.
Firdaous Khemlichi +2 more
doaj +1 more source
Journal of Risk and Insurance, EarlyView.Abstract Index insurance lowers agricultural risk but covers only covariate risks. Since farmers do not have complete insurance, they may develop mistrust of insurance when experiencing crop losses and not receiving payouts. Although recent innovations in remote sensing enable the provision of more complete insurance including coverage for ...
Berber Kramer +2 more
wiley +1 more source
Guangtongxin yanjiu, 2007 目前的发展趋势表明,T-MPLS（传送多协议标签交换）将逐渐成为一种新的传送机制。文章介绍了端到端PW（伪线）模型,分析了T-MPLS网络的信号封装机制,提出了基于PW的T-MPLS层网络与以太网互通模型。在此基础上文章结合T-MPLS信号封装机制,详细讨论了基于PW的以太网互通模型。
樊自甫, 万晓榆
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