Results 131 to 140 of about 69,250 (228)

Seasonal differences and potential biological drivers of the methane paradox in two peri‐Alpine lakes

Limnology and Oceanography Letters, Volume 11, Issue 3, May 2026.
Abstract Seasonal variations and the biological drivers underlying the methane paradox in freshwater lakes are poorly understood. Here, we investigated the relationship between subsurface methane inventories and phytoplankton in two peri‐Alpine lakes across different seasons.
Niharika Sharma, Manuela Felsberger, Zeynep Kurt, Markus Möst, Barbara Bayer   +4 more
wiley   +1 more source

Genomic evolution and natural history of myeloproliferative neoplasms on therapy. [PDF]

Cancer Discov
Leongamornlert D, Lee J, Kamizela AE, To K, Myers D, Williams N, Nyamondo K, Wang X, Guo J, Dissanayake RK, Price J, Durrani AJ, Lambert J, Spencer Chapman M, Pimanda JE, Baxter EJ, Green AR, Godfrey AL, Nangalia J.   +18 more
europepmc   +1 more source

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

MedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang, Xiaoqing Wang, Kai Luo, Tikam Chand Dakal, He Bai, Caiming Xu, Guixin Zhang   +6 more
wiley   +1 more source

MPN-FIT: a randomized controlled pilot trial of supervised exercise in myeloproliferative neoplasms. [PDF]

Blood Adv
Ouellet M, Rizzolo A, Venne C, Moussa H, Bilodeau K, Mollica L, Chabot-Roy G, Huynh-Trudeau G, Lesage S, Harnois M, Busque L, Sirhan S, Szuber N.   +12 more
europepmc   +1 more source

The Evolving Therapeutic Landscape of Gallic Acid: A Review of Mechanistic Insights and Clinical Potential

Molecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
ABSTRACT Gallic acid (GA), a plant‐derived phenolic compound, is evolving from a general antioxidant into a specific molecular modulator and a functional building block for advanced biomedical materials. This review synthesizes recent insights underpinned by GA's “redox duality”—its capacity to act as either a radical scavenger or a pro‐oxidant.
Woo Hyun Park
wiley   +1 more source

The Intricate Dance Between Inflammation and Myeloproliferative Neoplasms: From Origins to Outcomes. [PDF]

Curr Hematol Malig Rep
Fleischman AG.
europepmc   +1 more source

How Salmonella Works Under Osmotic and Desiccation Stresses

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Salmonella remains one of the leading threats in foods with reduced water activity, where it can survive for long periods and cause outbreaks. Its persistence stems from a wide array of adaptive strategies shaped by the selective pressures imposed by low‐moisture foods.
Mayara Messias Oliveira, Dionisio P. Amorim‐Neto, Anderson S. Sant'Ana   +2 more
wiley   +1 more source

Presynaptic chloride-dependent regulation of spontaneous glutamate release in the rat medial preoptic nucleus. [PDF]

Front Cell Neurosci
Pérez-Del-Pozo M, Kuznetsova T, Johansson S, Druzin M.   +3 more
europepmc   +1 more source

Quality Characteristics of Processed Opuntia ficus‐indica Using Selected Drying Techniques

Journal of Food Science, Volume 91, Issue 5, May 2026.
ABSTRACT This study aimed to develop and characterize the technological, physical, nutritional, and bioactive properties of cactus cladode flour (Opuntia ficus‐indica L.) obtained through freeze‐drying (OP‐FD) and air circulation oven drying (OP‐AC). The flours exhibited low water activity (OP‐AC: 0.410; OP‐FD: 0.501), moisture content (OP‐AC: 5.8 g ...
Nayane Medeiros Santos, Ana Cristina Silveira Martins, Jordania Candice Costa Silva, Maria Elizângela Ferreira Alves, Renally de Lima Moura, Carlos Eduardo Vasconcelos Oliveira, Marcos dos Santos Lima, Josean Fechine Tavares, Marcelo Sobral da Silva, Yuri Mangueira do Nascimento, Maria Elieidy Gomes de Oliveira, Vanessa Bordin Viera, Diego Elias Pereira, Juliana Késsia Barbosa Soares   +13 more
wiley   +1 more source

Leveraging paired germline and somatic analysis to improve the classification of DDX41 variants

British Journal of Haematology, Volume 208, Issue 5, Page 1584-1595, May 2026.
Summary Constitutional pathogenic variants in DDX41 predispose to myelodysplasia and acute myeloid leukaemia. Acquisition of subsequent somatic hits in the second allele is frequent, with notable recurrent variants at key hotspots. Sequencing of Deoxyribonucleic acid from blood/marrow of 239 patients with suspected/confirmed haematological malignancies
Andrew George, Elisabeth Rolf, Monika Domeradzka, Sara Ribeiro, Brittany Mills, April Hallett, Suzanne Macmahon, Paula Proszek, Ridwan Shaikh, Lina Yuan, Michael Hubank, Mikel Valganon Petrizan, Terri P. McVeigh, Jamshid S. Khorashad   +13 more
wiley   +1 more source