Results 1 to 10 of about 25,027 (154)
Chorea and Cognitive Impairment in JAK2V617F-Positive Myeloproliferative Disorders: A Case Report and Literature Review [PDF]
Medicina, 2023 Chorea is a hyperkinetic movement disorder, accompanied by dystonia, myoclonus, tics, stereotypies, and tremors. It is characterized by excessive, purposeless movements that are distressing, irregularly timed, and randomly distributed.
Ioana Butnariu +7 more
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A review of current knowledge of myeloproliferative disorders in the horse [PDF]
Acta Veterinaria Scandinavica, 2021 Myeloid disorders are conditions being characterized by abnormal proliferation and development of myeloid lineage including granulocytes (neutrophils, eosinophils and basophils), monocytes, erythroids, and megakaryocytes precursor cells. Myeloid leukemia,
Katy Satué +2 more
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Hereditary myeloproliferative disorders
Haematologica, 2010 Hereditary forms of myeloproliferative disorders (MPD) can be divided into two broad categories. First, inherited syndromes that affect a single lineage with Mendelian inheritance, high penetrance and polyclonal hematopoiesis, and second, inherited predisposition to true MPD, characterized by ...
Radek C. Skoda
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Platelet Function, Role in Thrombosis, Inflammation, and Consequences in Chronic Myeloproliferative Disorders [PDF]
Cells, 2021 Platelets are conventionally defined as playing a vital role in homeostasis and thrombosis. This role has over the years transformed as knowledge regarding platelets has expanded to include inflammation, cancer progression, and metastasis.
Lisa Repsold, Anna Margaretha Joubert
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Blood, 2008 Abstract In 1951 William Dameshek classified polycythemia vera (PV), essential thombocytosis (ET), and primary myelofibrosis (PMF) as pathogenetically related myeloproliferative disorders (MPD). Subsequent studies demonstrated that PV, ET, and PMF are clonal disorders of multipotent hematopoietic progenitors.
Ross L, Levine, D Gary, Gilliland
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IL-4 Serum Level Estimation in Myeloproliferative Neoplasm Patients
مجلة مركز بحوث التقنيات الاحيائية, 2022 Back Ground: Myeloproliferative neoplasm (MPN) is a long-term blood disease that has an excess production of mature hematopoietic pluripotent stem cells in the bone marrow. In the early fifties, W.
Ahmed Rushdi Abdullah
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Pathogenesis of Myeloproliferative Disorders [PDF]
Annual Review of Pathology: Mechanisms of Disease, 2016 Myeloproliferative neoplasms (MPNs) are a set of chronic hematopoietic neoplasms with overlapping clinical and molecular features. Recent years have witnessed considerable advances in our understanding of their pathogenetic basis. Due to their protracted clinical course, the evolution to advanced hematological malignancies, and the accessibility of ...
Nangalia, J, Grinfeld, J, Green, AR
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The role of the JAK2 GGCC haplotype and the TET2 gene in familial myeloproliferative neoplasms
Haematologica, 2011 Background Myeloproliferative neoplasms constitute a group of diverse chronic myeloid malignancies that share pathogenic features such as acquired mutations in the JAK2, TET2, CBL and MPL genes.
Damla Olcaydu +10 more
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Chronic myeloproliferative disorders: A rarest case with oral manifestations and dental management
Journal of Indian Academy of Oral Medicine and Radiology, 2012 Chronic myeloproliferative disorders (CMPD) are rarest hematological disorders (malignant myeloid neoplasms). The three most common chronic myeloproliferative disorders are polycythemia vera, essential thrombocythemia and chronic idiopathic myelofibrosis.
Pritesh B Ruparelia +3 more
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Molecular Genetics & Genomic Medicine, 2022 The JAK2 gene encodes for a non‐receptor tyrosine kinase that plays a key role in the JAK/STAT signaling transfer pathway. Genetic polymorphisms of this gene have been indicated to be associated with myeloproliferative neoplasm‐associated thrombosis in ...
Nguyen Thy Ngoc +3 more
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