Results 141 to 150 of about 36,802 (283)

Myelodysplasia‐Related Gene Mutation Burden Is Associated With Complete Remission After Induction Therapy in Acute Myeloid Leukemia, Not Otherwise Specified: Reclassification According to the Updated Classifications

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Updated classifications incorporating myelodysplasia‐related (MR) gene mutations reclassify many cases previously diagnosed as acute myeloid leukemia, not otherwise specified (AML, NOS). We evaluated the clinical significance of MR gene mutation burden, defined by mutation number and variant allele frequency (VAF), in AML, NOS ...
Taegeun Lee, Daehyun Chu, Miyoung Kim, Young‐Uk Cho, Sang‐Hyun Hwang, Je‐Hwan Lee, Yunsuk Choi, Eun‐Ji Choi, Ho Joon Im, Hyery Kim, Seongsoo Jang   +10 more
wiley   +1 more source

Arabidopsis inositol polyphosphate kinase activities regulate COP9 deneddylation functions in phosphate homeostasis

Journal of Integrative Plant Biology, EarlyView.
Plant phosphate (Pi) homeostasis relies on coordinated activities of the inositol polyphosphate kinases IPK1 and ITPK1, which balance localized InsP7 biosynthesis to control COP9 signalosome (CSN)‐dependent deneddylation of cullin 1 (CUL1). Perturbation of this equilibrium affects the stability of SPX4, a key negative regulator of phosphate starvation ...
Yashika Walia, Medha Noopur, Ishana Bhattacharya, Bhaskar Chandra Sahoo, Mritunjay Kasera, Naga Jyothi Pullagurla, Smritikana Dutta, Guizhen Liu, Gabriel Schaaf, Henning Jessen, Debabrata Laha, Souvik Bhattacharjee, Saikat Bhattacharjee   +12 more
wiley   +1 more source

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source

Longitudinal functional network connectivity changes across the clinical stages of C9orf72 hexanucleotide repeat expansion carriers. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Intrinsic functional connectivity network abnormalities in C9orf72 hexanucleotide repeat expansion carriers emerge during the asymptomatic phase, yet longitudinal studies remain limited. We examined cross‐sectional abnormalities and longitudinal connectivity changes across clinical stages.
Zhang L, Häkkinen S, Jung Y, Mandelli ML, Leichter D, Onyike CU, Rojas JC, Lombardi J, Gorno-Tempini ML, Yokoyama JS, Sturm VE, Kramer J, Boeve BF, Boxer AL, Forsberg LK, Heuer HW, Kantarci K, Ramos EM, Rosen HJ, Miller BL, Seeley WW, Flagan TM, Lee SE, ARTFL/LEFFTDS/ALLFTD Consortia.   +23 more
europepmc   +2 more sources

Engineered surface strategies to manage dental implant‐related infections

Periodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza, Bruna E. Nagay, Rodrigo Martins, Martinna Bertolini, Jamil A. Shibli, Conrado Aparicio, Magda Feres, Valentim A. R. Barão   +7 more
wiley   +1 more source

PO35 | Cerebral veins thrombosis in patients with and without myeloproliferative neoplasm: a real life retrospective monocentric study

Bleeding, Thrombosis and Vascular Biology
Background and Aims: Cerebral veins thrombosis (CVT) has an estimated annual incidence of 1 to 2 cases/100000 persons/year in the general population and it is more common in young adult females, largely due to risk factors as oral contraceptives ...
doaj   +1 more source

Microplastic Dynamics in Sediment Layers of Two Ramsar‐Designated Wetlands

Water and Environment Journal, EarlyView.
ABSTRACT Little is known about the vertical and spatial dynamics of microplastics in relation to hydrology and land use, particularly in African context. This study aimed to assess the abundance, type, colour and vertical distribution of microplastics in sediment from two Ramsar‐designated wetlands, the Makuleke and Nylsvley. Sediment core samples were
Nelisiwe Ngomane, Linton F. Munyai, Ross N. Cuthbert, Pule Mpopetsi, Farai Dondofema, Rabelani Mudzielwana, Philippa Huchzermeyer, Tatenda Dalu   +7 more
wiley   +1 more source

Aquagenic Pruritus Questionnaire: Predicting Myeloproliferative Neoplasms in Patients with Aquagenic Pruritus

Dermatology and Therapy
Introduction Aquagenic pruritus (AP) is an underrecognized condition in which patients perceive itch following contact with water on clinically non-lesional skin.
Felix Witte, Elke Weisshaar, Martin Metz, Steffen Koschmieder, Susanne Isfort, Andreas E. Kremer, Martin Griesshammer, Svenja Royeck, Sonja Ständer, Claudia Zeidler   +9 more
doaj   +1 more source

MPN nafi diskusi meja bulat bias [PDF]

, 2013
Alor Setar: Majlis Profesor Negara (MPN) menafikan diskusi meja bulat dianjur pihaknya bertujuan menyuntik idea kepada pengundi negara ini supaya memilih parti ...
Berita, Harian
core  

Neotropical Snakes Reveal Different Geological Times for Dispersal Corridors Between Amazon and Atlantic Forests

Zoologica Scripta, EarlyView.
ABSTRACT Three forested dispersal corridors have been proposed within the diagonal of open/dry landscapes in South America and the relative importance of each one has been the subject of debate for forest organisms. We analysed the biogeographical history of three snake genera (Bothrops, Philodryas, and Micrurus) from different families (Viperidae ...
Matheus Pontes‐Nogueira, Tiago F. Carrijo, Ricardo J. Sawaya   +2 more
wiley   +1 more source