Results 191 to 200 of about 69,250 (228)

Myeloproliferative Neoplasien (MPN)

Der Klinikarzt, 2020
ZUSAMMENFASSUNGAls „Myeloproliferative Neoplasien“ (MPN) werden eine Gruppe verschiedener maligner chronischer Erkrankungen der blutbildenden (Stamm-)Zellen des Knochenmarkes bezeichnet. Kennzeichnend für dieses Krankheitsbild ist eine gesteigerte Produktion von Erythrozyten, Leukozyten und/oder Thrombozyten.
Kim Kricheldorf, Tim H. Brümmendorf, Steffen Koschmieder   +2 more
openaire   +1 more source

Mutational landscape of blast phase myeloproliferative neoplasms (MPN-BP) and antecedent MPN

2022
Myeloproliferative neoplasms (MPN) have an inherent tendency to evolve to the blast phase (BP), characterized by ≥20% myeloblasts in the blood or bone marrow. MPN-BP portends a dismal prognosis and currently, effective treatment modalities are scarce, except for allogeneic hematopoietic stem cell transplantation (allo-HSCT) in selected patients ...
Sergiu, Pasca, Helen T, Chifotides, Srdan, Verstovsek, Prithviraj, Bose   +3 more
openaire   +2 more sources

Immunotherapy for Myeloproliferative Neoplasms (MPN)

Current Cancer Drug Targets, 2011
The four major entities that form the group of myeloproliferative neoplasms (MPN) are BCR-ABL positive chronic myeloid leukaemia (CML), chronic idiopathic myelofibrosis (CIMF), essential thrombocythemia (ET) and polycythemia vera (PV). All four are clonal diseases of the haematopoietic stem or precursor cell, they are of a chronic nature and ...
Susanne, Hofmann, Anna, Babiak, Jochen, Greiner   +2 more
openaire   +2 more sources

Direct MPN for Faecal Coliform

Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite Naturwissenschaftliche Abteilung: Mikrobiologie der Landwirtschaft, der Technologie und des Umweltschutzes, 1980
Samples of Nile and Ismailia canal water were subjected to direct inoculation and incubation at elevated temperatures. The results obtained showed that the use of MacConkey broth medium was better than EC broth. In addition, the Direct MPN technique revealed to be suitable and superior by 90% of the examined samples.
M M, el-Abagy, H T, el-Zanfaly, S, el-Hawaary   +2 more
openaire   +2 more sources

Overcoming “aspirin resistance” in MPN

Blood, 2012
In this issue of Blood, Pascale and colleagues show that biochemical resistance to aspirin in patients with essential thrombocythemia (ET) can be reversed by twice-daily dosing ...
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Increasing therapeutic efficacy in MPN

Blood, 2014
In this issue of Blood, Bhagwat et al describe an elegant series of experiments showing that genetic deletion in the hematopoietic system of Janus kinase 2 (JAK2) abrogates initiation of myeloproliferative disease and substantial disease regression if deleted once disease is initiated.
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Treatment of MDS/MPN and the MDS/MPN IWG International Trial: ABNL MARRO

Current Hematologic Malignancy Reports, 2019
MDS/MPNs comprise a group of rare hematologic malignancies that balance features of myeloproliferation and bone marrow failure. Given overlapping clinical features and rarity of incidence, MDS/MPNs have long posed a diagnostic and therapeutic challenge.
Andrew T, Kuykendall, Eric, Padron
openaire   +2 more sources

Sexuality Challenges, Intimacy, and MPN Symptom Burden: An Analysis By The MPN Quality Of Life International Study Group (MPN-QOL ISG)

Blood, 2013
Abstract Background We have previously reported on the high prevalence and severity of challenges with intimacy and sexuality amongst a large international cohort of MPN patients (Emanuel JCO 2012). We sought to further analyze the relationships between issues of intimacy (sexual desire and function),
H.L., Geyer, A.C., Dueck, R.M., Emanuel, K., Cannon, J.-J., Kiladjian, S., Slot, S., Zweegman, P., Boekhorst, S., Commandeur, H.C., Schouten, F., Sackmann, A.K., Fuentes, D., Hernandez, H.L., Pahl, M., Griesshammer, F., Stegelmann, K., Döhner, T., Lehmann, D., Ranta, A., Reiter, F., Boyer, G., Etienne, J.-C., Ianotto, L., Roy, J.-Y., Cahn, C.N., Harrison, D.H., Radia, P.J., Muxi, N.I., Maldonado, C., Besses, F., Cervantes, P., Johansson, T., Barbui, G., Barosi, A.M., Vannucchi, F., Passamonti, B., Andreasson, M., Ferrari, A., Rambaldi, J., Samuelsson, G., Birgegard, Z., Xiao, Z., Xu, X., Sun, J., Xu, P., Zhang, R.P., Gale, R.A., Mesa   +47 more
openaire   +4 more sources

Itchy mast cells in MPNs

Blood, 2009
In this issue of Blood, Ishii and colleagues investigate the role of mast cells in the pathogenesis of pruritus in patients with MPNs.
openaire   +2 more sources

Myeloproliferative Neoplasien (MPN)

Der Klinikarzt, 2018
ZusammenfassungMyeloproliferative Neoplasien (MPN) sind klonale Stammzellerkrankungen, die typischerweise mit der Vemehrung einer oder mehrerer Blutzellreihen, einer Knochenmarkhyperplasie und einer (Hepato)-Splenomegalie als Zeichen der extramedullären Hämatopoese einhergehen. Gefürchtete Komplikationen der MPN sind
Steffen Koschmieder, Tim H. Brümmendorf
openaire   +1 more source