Results 1 to 10 of about 5,276 (179)

Superficial malignant peripheral nerve sheath tumor from recurrent neurofibroma in the abdominal wall of a patient without neurofibromatosis type 1 [PDF]

open access: yesYeungnam University Journal of Medicine, 2019
Malignant peripheral nerve sheath tumor (MPNST) is rare, accounting for 5–10% of all soft tissue sarcomas. MPNST is characteristically aggressive and has a poor prognosis. Fifty percent of patients with MPNST have neurofibromatosis type 1 (NF1).
Chang Yeon Jung   +3 more
doaj   +1 more source

HDAC8, A Potential Therapeutic Target for the Treatment of Malignant Peripheral Nerve Sheath Tumors (MPNST). [PDF]

open access: yesPLoS ONE, 2015
HDAC isoform-specific inhibitors may improve the therapeutic window while limiting toxicities. Developing inhibitors against class I isoforms poses difficulties as they share high homology among their catalytic sites; however, HDAC8 is structurally ...
Gonzalo Lopez   +9 more
doaj   +1 more source

Diagnosis and treatment of the giant malignant peripheral nerve sheath tumor in the anterior mediastinum: A case report

open access: yesDigital Diagnostics, 2023
INTRODUCTION: Malignant peripheral nerve sheath tumor (MPNST) occurs in young and middle-aged people, more frequently in those with the genetic disease known as neurofibromatosis type 1 (NF1).
Anna A. Gofman   +4 more
doaj   +1 more source

Multiplatform molecular profiling uncovers two subgroups of malignant peripheral nerve sheath tumors with distinct therapeutic vulnerabilities

open access: yesNature Communications, 2023
Malignant peripheral nerve sheath tumor (MPNST) is a highly aggressive sarcoma, and a lethal neurofibromatosis type 1-related malignancy, with little progress made on treatment strategies.
Suganth Suppiah   +23 more
doaj   +1 more source

Impaired Pten expression in human malignant peripheral nerve sheath tumours. [PDF]

open access: yesPLoS ONE, 2012
Malignant peripheral nerve sheath tumours (MPNST) are aggressive sarcomas that develop in about 10% of patients with the genetic disease neurofibromatosis type 1 (NF1).
Maren Bradtmöller   +12 more
doaj   +1 more source

Huge Malignant Peripheral Nerve Sheath Tumors Originating In Neurofibromatosis Type 1

open access: yesJournal of Rawalpindi Medical College, 2023
Malignant peripheral nerve sheath tumors (MPNST) are malignant soft tissue neoplasms which account for 2% of all soft tissue sarcomas. These tumors are associated with poor prognosis, propensity to metastasize and high recurrence rates.
Nabeela Riaz, Samreen Younas
doaj   +1 more source

Case report: Brachial plexopathy caused by malignant peripheral nerve sheath tumor and review of the literature

open access: yesFrontiers in Neurology, 2023
Brachial plexopathy (BP) is easily misdiagnosed due to its complexity and varying clinical presentation. Malignant peripheral nerve sheath tumors (MPNST) can accumulate in the brachial plexus and share symptoms with BP, which may hinder the differential ...
Mengjie Chen, Xiuli Li, Xinhong Feng
doaj   +1 more source

A worldwide bibliometric analysis of malignant peripheral nerve sheath tumors from 2000 to 2022

open access: yesFrontiers in Oncology, 2023
BackgroundCurrently, malignant peripheral nerve sheath tumors (MPNST) are the subject of intense research interest. However, bibliometric studies have not been conducted in this field.
Xingfeng Huang   +11 more
doaj   +1 more source

Radiology Appearance of Malignant Peripheral Nerve Sheath Tumor: a Case Report

open access: yesIndonesian Journal of Cancer, 2009
Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue sarcoma. This tumor included up to 10% of 1-2 of 100,000 population/year soft tissue sarcoma.
Aziza G Icksan   +3 more
doaj   +1 more source

Expression and inhibition of BRD4, EZH2 and TOP2A in neurofibromas and malignant peripheral nerve sheath tumors.

open access: yesPLoS ONE, 2017
Malignant peripheral nerve sheath tumors (MPNST) are rare, highly aggressive sarcomas that can occur spontaneously or from pre-existing plexiform neurofibromas in neurofibromatosis type1 (NF1) patients.
Azadeh Amirnasr   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy