Results 21 to 30 of about 5,276 (179)

BCRP expression in schwannoma, plexiform neurofibroma and MPNST

Oncotarget, 2017
peripheral nerve sheath tumors comprise a broad spectrum of neoplasms. Vestibular schwannomas and plexiform neurofibromas are symptomatic albeit benign, but a subset of the latter pre-malignant lesions will transform to malignant peripheral nerve sheath tumors (MPNST). Surgery and radiotherapy are the primary strategies to treat these tumors. Intrinsic
Vries, M. de, Tellingen, O. van, Mey, A.G.L. van der, Bunt, A.M.G., Briaire-de Bruijn, I., Hogendoorn, P.C.W.   +5 more
openaire   +5 more sources

Outcomes and Prognostic Factors in Patients with Malignant Peripheral Nerve Sheath Tumor

Siriraj Medical Journal, 2021
Objective: To investigate and report the clinical profiles, treatment patterns, and oncologic outcomes in MPNST patients, and to identify the prognostic factors that significantly affect survival.
Chindanai Hongsaprabhas, Sorranart Muangsomboon, Chandhanarat Chandhanayingyong, Rapin Phimolsarnti, Saranatra Waikakul, Apichat Asavamongkolkul   +5 more
doaj   +1 more source

The 4q12 amplicon in malignant peripheral nerve sheath tumors: consequences on gene expression and implications for sunitinib treatment. [PDF]

PLoS ONE, 2010
Malignant peripheral nerve sheath tumors (MPNST) are highly aggressive tumors which originate from Schwann cells and develop in about 10% of neurofibromatosis type 1 (NF1) patients.
Jan Zietsch, Nicolas Ziegenhagen, Frank L Heppner, David Reuss, Andreas von Deimling, Nikola Holtkamp   +5 more
doaj   +1 more source

MMP-13, p53 in the Progression of Malignant Peripheral Nerve Sheath Tumors

Neoplasia: An International Journal for Oncology Research, 2007
Malignant peripheral nerve sheath tumors (MPNST) are sarcomas with poor prognosis, limited treatment options. Factors contributing to tumor progression are largely unknown.
Nikola Holtkamp, Isis Atallah, Ali-Fuat Okuducu, Jana Mucha, Christian Hartmann, Victor-F Mautner, Reinhard E. Friedrich, Christian Mawrin, Andreas von Deimling   +8 more
doaj   +1 more source

Une tumeur maligne des gaines des nerfs périphériques compliquant la maladie de Von Recklinghausen

The Pan African Medical Journal, 2015
Les tumeurs malignes des gaines des nerfs périphériques ou MPNST (Malign Peripheral Nerve Sheath Tumors selon les anglo-saxons) sont des tumeurs rares qui constituent la principale complication des neurofibromatoses de type 1 (NF1) à l'âge adulte.
Tilila Hajjad, Samir El Mazouz, Noureddine Gharib, Abdellah El Abbassi   +3 more
doaj   +1 more source

Malignant peripheral nerve sheath tumor presenting as sciatica in a patient with neurofibromatosis type 1: is magnetic resonance imaging an effective screening tool?

European Journal of Case Reports in Internal Medicine
Peripheral malignant nerve sheath tumours (MPNST) are rare and aggressive soft tissue sarcomas often associated with neurofibromatosis type I (NF-1). We describe a case of a 26-year-old female with NF-1, initially misdiagnosed as sciatica, who was later ...
Adisalem M. Teferi, Sangam Sangam, Azana Newman, Osman Alvarado, Irvianny Madera, Julian Paniagua   +5 more
doaj   +1 more source

Retroperitoneal Malignant Peripheral Nerve Sheath Tumour: A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2015
Malignant nerve sheath tumours (MPNST) are rare neoplasias and retroperitoneal cases are fairly rare and clinically difficult to be detected, but they are very agressive neoplasias. MPNST are frequently seen in head, neck and upper extremities.
Ayse Nur Deger, Mehmet Akif Bayar, Muzaffer Caydere, Hakki Deger, Mahir Tayfur   +4 more
doaj   +1 more source

Radiotherapy Offered Limited Additional Benefits on Cancer-specific Survival for Patients with Resectable Subcutaneous Malignant Peripheral Nerve Sheath Tumors: A Population-based Retrospective Cohort Analysis

Neurologia Medico-Chirurgica
For resectable malignant peripheral nerve sheath tumors, the additional benefits of radiotherapy remain controversial. This study aims to investigate whether there is an additional benefit of radiotherapy for resectable malignant peripheral nerve sheath ...
Yiding XIAO, Zhujun LI, Bozhi HU, Hailin ZHANG   +3 more
doaj   +1 more source

Malignant Peripheral Nerve Sheath Tumor: MRI and CT Findings

Case Reports in Radiology, 2015
This is a case report of a 56-year-old male with hypertension who presented with urinary retention and bowel incontinence. CT and MRI of the abdomen and pelvis showed a large complex cystic and solid enhancing mass in the right presacral space. Pathology
K. O. Kragha
doaj   +1 more source

Testing ATRA and MEK inhibitor PD0325901 effectiveness in a nude mouse model for human MPNST xenografts

BMC Research Notes, 2018
Objective Malignant peripheral nerve sheath tumors (MPNST) are aggressive sarcomas characterized by high recurrence rates and early metastases. These tumors arise more frequently within neurofibromatosis type 1 (NF1) and present with resistance during ...
Susan Fischer-Huchzermeyer, Levan Chikobava, Verena Stahn, Monique Zangarini, Philip Berry, Gareth J. Veal, Volker Senner, Victor F. Mautner, Anja Harder   +8 more
doaj   +1 more source