Results 111 to 120 of about 16,708 (231)

Impaired Cellular Immunity and Cross‐Reactive Humoral Responses to Mpox Virus in HIV‐Infected Individuals Vaccinated with Vaccinia Virus Tiantan Strain

MedComm, Volume 6, Issue 12, December 2025.
This study examines MPXV immunity in PLWH, focusing on smallpox vaccine‐induced responses. PLWH with CD4⁺ T‐cell counts <500 cells/mm3 showed reduced VTT‐IgG, MPXV‐IgG, and NAbs, while CD4⁺ T‐cell responses were impaired at counts <350 cells/mm3. CD8⁺ T‐cell responses remained stable.
Qiao Zhang, Rui Song, Yu Huang, Meiyu Fang, Xiaoyou Chen, Danyang Li, Yanan Li, Xueqi Chi, Fengwen Xu, Jingchuan Zhong, Lan Chen, Zhixia Gu, Hongxin Zhao, Yuanyuan Zhang, Ning Han, Elie Antoun, Yanchun Peng, Tao Dong, Li Guo, Fei Guo, Lili Ren, Jianwei Wang, Ronghua Jin   +22 more
wiley   +1 more source

Advancing the understanding and management of Mpox: insights into epidemiology, disease pathways, prevention, and therapeutic strategies [PDF]

Mpox, previously known as monkeypox, is a zoonotic viral disease caused by the Mpox virus (MPXV), a member of the Orthopoxvirus genus. This disease is of significant concern due to its zoonotic transmission, which can be challenging to control, its ...
Abusara, Osama H., Bardaweel, Sanaa K., Hajjo, Rima, Sabbah, Dima A.   +3 more
core   +2 more sources

Changes in HIV‐1 Reservoir Dynamics After Mpox Infection

Journal of Medical Virology, Volume 97, Issue 11, November 2025.
ABSTRACT In May 2022, a large outbreak of monkeypox virus (MPXV) occurred in several non‐endemic regions worldwide. Another outbreak in 2024 raised global concerns, particularly for immunocompromised individuals like people with HIV (PWH). Since the latent HIV‐1 reservoir remains a major barrier to a cure, we investigated how past mpox infection ...
Guiomar Casado‐Fernández, Olivia de la Calle‐Jiménez, Inés Armenteros, Luis Lemus Aguilar, Daniel Fuertes, Juan Cantón, Elena Mateos, Noemi Cabello, Javier Rodríguez Añover, Anabel Negredo, Miguel Cervero, María Paz Sánchez Seco, Montserrat Torres, Vicente Estrada, Mayte Coiras   +14 more
wiley   +1 more source

A bivalent Mpox nanoparticle vaccine induces robust immune response and provides long-lasting protection against vaccinia virus challenge

Emerging Microbes and Infections
The 2022 and 2024 monkeypox (mpox) outbreak highlighted the urgent need for effective, durable, and safe vaccines. In addition to the traditional smallpox vaccines that could bring cross-protection against mpox, mRNA and protein-subunit mpox vaccines ...
Yanhai Wang, Hao Sun, Huixu Zhou, Wenxue Yang, Sha Li, Mengchan Hao, Haiyan Chang, Yuan Zhang, Yun Wang, Jianjun Chen   +9 more
doaj   +1 more source

Monkeypox (Mpox): Diagnosis and Emerging Challenges

The Yale Journal of Biology and Medicine
Monkeypox (Mpox) has once again been designated a Public Health Emergency of International Concern (PHEIC) as of August, 2024. The severity of the disease is underscored by its significant mortality rate, and unfortunately, there are no targeted therapeutics currently available for this viral infection.
Krishna, Smriti, Teotia, Dimpi, Yadav, Manisha, Mahilkar, Shakuntala, Suchiita, Anuupama, Saxena, Abhishweta, Sonkar, Subash Chandra, Chandra, Lal, Koner, Bidhan Chandra   +8 more
openaire   +2 more sources

The Stigmatisation of Men Who Have Sex With Men in the Spread of Mpox: Are We Repeating the Mistakes of HIV?

Nursing Open, Volume 12, Issue 11, November 2025.
ABSTRACT The 2022 mpox outbreak disproportionately affected men who have sex with men (MSM), leading to targeted public health interventions. While data supported prioritising MSM, this focus risks reviving stigmatisation reminiscent of the HIV/AIDS crisis.
David Bermejo‐Martínez, Enrique Castro‐Sánchez, Pilar Marqués‐Sánchez   +2 more
wiley   +1 more source

Self-reported Infection Status, Knowledge and Associated Factors of Monkeypox Among Men Who Have Sex with Men in Jiaxing, China

BMC Public Health
Background As of September 2023, more than 1,000 cases of monkeypox (mpox) have been reported in China. Based on the available evidence, men who have sex with men (MSM) are at high risk for mpox infection.
Yangyang Tian, Zhigang Hou, Guoying Zhu, Qianqian Zhang, Wutong Zhu, Hao Feng, Weizhe Pan, Qiang Li, Rui Ge, Zhongwen Chen   +9 more
doaj   +1 more source

Mpox and Surgery: Protocols, Precautions, and Recommendations

Microorganisms
Mpox, also known as Monkeypox, is an infectious disease known to spread via direct contact and fomites, which poses a significant contagion risk in surgical settings and may increase the challenges already posed by COVID-19.
Nikolaos Kamaratos-Sevdalis, Islam Kourampi, Nazli Begum Ozturk, Anna C. Mavromanoli, Christos Tsagkaris   +4 more
doaj   +1 more source

Coupling wastewater‐based epidemiology with data‐driven machine learning for managing public health risks

Risk Analysis, Volume 45, Issue 10, Page 2974-2982, October 2025.
Abstract Traditional health surveillance methods play a critical role in public health safety but are limited by the data collection speed, coverage, and resource requirements. Wastewater‐based epidemiology (WBE) has emerged as a cost‐effective and rapid tool for detecting infectious diseases through sewage analysis of disease biomarkers.
Sheree Pagsuyoin, Calvin Ng, Nerissa Molejon, Yan Luo   +3 more
wiley   +1 more source

Monkeypox virus-associated meningoencephalitis diagnosed by detection of intrathecal antibody production

BMC Infectious Diseases
Background In the 2022 mpox-outbreak most patients presented with mild symptoms. Central nervous system (CNS) involvement has previously been described as a rare and severe complication of mpox; however, diagnostic findings in cerebrospinal fluid (CSF ...
Hansen Karin, Båtshake Ylva, Söderholm Sandra, Pettke Aleksandra, Björkman Per, Sondén Klara   +5 more
doaj   +1 more source