Results 141 to 150 of about 1,669,562 (240)

Laryngeal Cancer Survival in Northern United Kingdom: A Multi‐Centre Retrospective Observational Study

Clinical Otolaryngology, EarlyView.
ABSTRACT Objectives Laryngeal cancer incidence has risen globally, yet survival outcomes have shown limited improvement over recent decades. This study evaluated contemporary outcomes across multiple centres in Northern UK and examined stage‐ and treatment‐specific survival. Design Multi‐centre retrospective observational study.
Amar Rajgor, Rhona Hurley, Catriona M. Douglas, Claire Paterson, James Moor, Shane Lester, Sara Sionis, Katherine Davies, James O’Hara, Gareth Inman, Terry Jones, David Winston Hamilton, Northern Head & Neck Alliance, Amarkumar Rajgor, Rhona Hurley, Catriona M. Douglas, Claire Paterson, James Moor, Shane Lester, Sara Sionis, Katherine Davies, James O'Hara, Gareth Inman, Terry Jones, David Winston Hamilton, Sarah Hill, Seamus O'Neill, Alison McLoughlin, Jemy Jose, Winson Wong, Michael Ho, Debbie Horne, Jarrod Homer, Matthew Kennedy, Emma Kinloch, Robert Metcalf, Iain Varley, Thomas Carroll, Sarah Healy, Helen Cocks, Michael Nugent, Leo Vassilou, Panos Kyzas, David Conway, John Greenman, Andrew Schache, Jason Fleming, Joanne Patterson, Keith Hunter, Paula Parvulescu, Rachel Brooker, Richard Shaw, Stephanie Meysner, Ola Rominiyi, Olena Mandrik   +54 more
wiley   +1 more source

SKY92 Identifies High‐Risk Newly Diagnosed Multiple Myeloma With Inferior Progression‐Free Survival and Implicates NUF2 as a Candidate Driver

European Journal of Haematology, EarlyView.
ABSTRACT Objectives To determine the prevalence and prognostic significance of the SKY92 gene‐expression signature, evaluate minimal/measurable residual disease (MRD), and identify molecular drivers of high‐risk disease in transplant‐eligible newly diagnosed multiple myeloma (TE‐NDMM) patients in the Republic of Ireland.
Roisin M. McAvera, Izabela Cymer, John Quinn, Phillip T. Murphy, Patrick Thornton, Niamh McAuley, Harmony Black, Omar Abdelzaher, Catherine Duane, Tatiana Cichocka, Eva Szegezdi, Meegahage Perera, Gerard M. Crotty, Michelle Connolly, Aileen Walsh, Ruth Clifford, Janusz Krawczyk, Teresa Meenaghan, Vitaliy Mykytiv, Ezzat Elhassadi, Mark Coyne, Robert J. Cummins, Rowan Kuiper, Michael O'Dwyer, Siobhan V. Glavey   +24 more
wiley   +1 more source

Initial clinical applications treating pediatric and adolescent patients using MR-guided radiotherapy. [PDF]

Front Oncol, 2022
Kozak MM, Crompton D, Gross BA, Harshman L, Dickens D, Snyder J, Shepard A, St-Aubin J, Dunkerley D, Hyer D, Buatti JM.   +10 more
europepmc   +1 more source

Treatment Patterns, Outcomes and Survival Trends in T‐Cell Prolymphocytic Leukemia: A Nationwide Population‐Based Study in the Netherlands

European Journal of Haematology, EarlyView.
ABSTRACT Background T‐cell prolymphocytic leukemia (T‐PLL) is a rare, aggressive mature T‐cell malignancy with limited therapeutic options. Alemtuzumab remains the backbone of therapy, and fit responders are consolidated with allogeneic stem cell transplantation (alloSCT). However, contemporary population‐level outcomes remain poorly defined.
Mirian Brink, Arie C. van der Spek, Jeanette K. Doorduijn, Koen de Heer, Sabina Kersting, Lidwine W. Tick, Doreen G. te Raa, Hanneke M. van der Straaten, Gerrit Jan Veldhuis, Laurens Laterveer, Rogier Mous, Mark‐David Levin, Kees Meijer, Andre Mulder, M. Nijland, Gerwin Huls, Arnon P. Kater, Mar Bellido   +17 more
wiley   +1 more source

Cross-fraction prior learning for scalable organ-at-risk segmentation in abdominal MR-guided radiotherapy. [PDF]

Med Phys
Li C, Rusu D, Sultan R, Bagher-Ebadian H, Doemer A, Zhu D, Parikh PJ, Thind K.   +7 more
europepmc   +1 more source

Generative Artificial Intelligence for Computer Vision in Endodontics: A Review of Current State and Future Potential

International Endodontic Journal, EarlyView.
ABSTRACT Background Computer vision methods based on artificial intelligence (AI) have found numerous applications in endodontic diagnosis and treatment planning. While most current applications employ discriminative deep learning models for detection and classification tasks, the field is now witnessing the rise of generative AI (GenAI), a class of AI
Hossein Mohammad‐Rahimi, Sanyam Jain, Khuram Naveed, Sepanta Hosseinpour, Lise‐Lotte Kirkevang, Ali Nosrat, Ruben Pauwels   +6 more
wiley   +1 more source

Evaluation of inter-fractional anatomical variations due to compression belt placement reproducibility using MR-guided radiotherapy treatment fraction images. [PDF]

J Appl Clin Med Phys
Shay O, Solis D, Aire M, Schneider C, Kirby K.   +4 more
europepmc   +1 more source

Mesorectal motion evaluation in rectal cancer MR-guided radiotherapy: an exploratory study to quantify treatment margins. [PDF]

Radiat Oncol, 2023
Boldrini L, Chiloiro G, Cusumano D, Romano A, Placidi L, Turco G, Antonelli MV, Nardini M, Galetto M, Indovina L, Gambacorta MA.   +10 more
europepmc   +1 more source

Advancing the frontiers of MR-guided radiotherapy for pancreatic cancer

Pancreatic cancer is among the deadliest types of cancer, and effective and safe treatment remains challenging. MR-guided radiotherapy, a noninvasive, low-toxic, local treatment, has recently emerged as a new treatment option for inoperable pancreatic ...
Grimbergen, Guus
core  

The Random Power Function for Tests Based on Pivotal Quantities

International Statistical Review, EarlyView.
Summary In clinical trials planning, evaluation of the probability of success of an experiment is of central interest, for instance, in sample size determination. This assessment typically involves analyses of the power function of a test on a parameter of interest, such as a relevant treatment effect.
Fulvio De Santis, Stefania Gubbiotti, Francesco Mariani   +2 more
wiley   +1 more source