Results 11 to 20 of about 301,410 (296)
TRPML1 agonist ML-SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux. [PDF]
FEBS Open BioTGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Yao J +10 more
europepmc +2 more sources
Population-based Research in South Wales: The MRC Pneumoconiosis Research Unit and the MRC Epidemiology Unit [PDF]
, 2002 ©The Trustee of the Wellcome Trust, London, 2002. First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2002. All volumes are freely available online at: www.history.qmul.ac.uk/research/modbiomed/wellcome_witnesses/Annotated ...
Ness, AR, Reynolds, LA, Tansey, EM
core +4 more sources
Metabolic regulation of MRC organization [PDF]
, 2022 65 p.-7 fig.-1 tab.-7 fig. suppl.The structural and functional organization of the mitochondrial respiratory chain (MRC) remains intensely debated. Here, we show the co-existence of two separate MRC organizations in human cells and postmitotic tissues, C-
Pitceathly, Robert D. S. +25 more
core +1 more source
PR-MRC: MRC Construction using Non-statistical Sampling [PDF]
, 2022 Miss ratio curves (MRCs) play an important role for visualizing and deciding on an effective cache size for a given workload. Unfortunately, generating exact MRCs require processing and memory overheads that are not practical for online use in production
Lee, Albert
core +1 more source
No confidence in the MRC [PDF]
QJM, 2003 As anyone interested in biomedical research must know, the House of Commons Science and Technology Committee recently issued a highly critical report on the workings of the UK’s Medical Research Council (MRC). Even at a time when the world’s journalists were preoccupied with the war in Iraq, the report made headlines: ‘Diabolical incompetence’, wrote ...
openaire +3 more sources
mrc-ide/cepi_retrospective_analysis: Version 1 Release
, 2023 Release of analysis of retrospective impact of 100 Days Mission. Main Outputs are found in: analysis/plots - Plots of all main results analysis/data/out - Data outputs and summary tables Full Changelog: https://github.com/mrc-ide ...
OJ Watson, GBarnsley
core +1 more source
The frequency and validity of self-reported diagnosis of Parkinson's Disease in the UK elderly: MRC CFAS cohort [PDF]
, 2006 Background: Estimates of the incidence and prevalence of chronic diseases can be made using established cohort studies but these estimates may have lower reliability if based purely on self-reported diagnosis.Methods: The MRC Cognitive Function & Ageing ...
MRC CFAS, The +13 more
core +2 more sources
Preparation For The MRCS In Surgery [PDF]
Journal of the Royal Army Medical Corps, 2004 The MRCS is an examination in a state of flux at the moment and the precise requirements of the forthcoming intercollegiate examinations are still awaited, but it is expected that many of its features will be directly translated from the current arrangements.
openaire +2 more sources
Revista Brasileira de Cancerologia, 2023 Com o objetivo de analisar o número de linfonodos dissecados, foram estudados 229 pacientes portadoras de câncer de mama, tratadas no Hospital Araújo Jorge entre 1979 e 1988.
Geraldo S. Queiroz +7 more
doaj +1 more source
ALLELES ASSOCIATED TO DISEASE SEVERITY INDEX OF MAL DE RÍO CUARTO DISEASE IN MAIZE EXOTIC GERMPLASM [PDF]
BAG. Journal of Basic and Applied Genetics, 2020 Mal de Río Cuarto (MRC) is one of the most important viral diseases of maize in Argentina. The disease severity index (DSI) allows to combine the incidence and severity of a disease in a single metric.
Rossi E.A. +3 more
doaj +1 more source