Results 51 to 60 of about 278,920 (305)
Turkish Journal of Hematology, 2021 Objective: This study aimed to investigate the clinical characteristics of acute myeloid leukemia with myelodysplasia-related changes (AMLMRC) according to the 2016 World Health Organization classification and the preferred therapy for patients with AML ...
Lei Wang +6 more
doaj +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan +14 more
wiley +1 more source
Metarepresentational competence in quantum mechanics change of basis problems
Physical Review Physics Education ResearchMetarepresentational competence (MRC) is a theoretical framework that is used to analyze how people create and interact with external representations.
Idris Malik, Warren Christensen
doaj +1 more source
PR-MRC: MRC Construction using Non-statistical Sampling
, 2022 Miss ratio curves (MRCs) play an important role for visualizing and deciding on an effective cache size for a given workload. Unfortunately, generating exact MRCs require processing and memory overheads that are not practical for online use in production
Lee, Albert
core
A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley +1 more source
Annals of Saudi MedicineBACKGROUND: Type 2 diabetes mellitus (T2DM) is a widespread chronic disease that poses a significant management challenge due to the complexity of the associated medication regimens, which can have a considerable impact on patient outcomes.
Sarah M. Khayyat +7 more
doaj +1 more source
Human genetic variation and disease
, 2016 The data forms part of the Resource pack Human genetic variation and disease, which is a real data resource to allow students to explore genetic and phenotypic data as part of their Scottish Qualifications Authority Nat5 or Higher Biology Assignment ...
Kerr, Shona +3 more
core +1 more source
Chronic myeloid leukemia stem cells display alterations in expression of genes involved in oxidative phosphorylation [PDF]
, 2012 The mitochondrial respiratory chain (MRC) consists of protein complexes I, II, III, IV and V that support oxidative phosphorylation (OXPHOS), which depends on electron transport to generate adenosine triphosphate (ATP).
Flis, Krzysztof +9 more
core +1 more source