Results 151 to 160 of about 122,119 (357)
Diabetes, Obesity and Metabolism, EarlyView.Abstract The clinical management of metabolic dysfunction‐associated steatotic liver disease (MASLD) and metabolic dysfunction‐associated steatohepatitis (MASH) is undergoing rapid evolution, driven by advances in noninvasive diagnostics and the recent approval of liver‐directed therapies.
Fernando Bril
wiley +1 more source
POS0965 MAGNETIC RESONANCE ENTEROGRAPHY AS A SCREENING TOOL FOR AXIAL SPONDYLOARTHRITIS IN CROHN'S DISEASE: A PROSPECTIVE SINGLE-CENTER CROSS-SECTIONAL OBSERVATIONAL STUDY USING MRE SCREENING FOLLOWED BY CLINICAL ASSESSMENT (ProSpA-CD) [PDF]
, 2022 J. Evans +9 more
openalex +1 more source
The FEBS Journal, EarlyView.Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal +8 more
wiley +1 more source
The FEBS Journal, EarlyView.Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy +7 more
wiley +1 more source
Journal of Gastroenterology and Hepatology, EarlyView.ABSTRACT Background and Aims Accurate assessment of advanced fibrosis and steatosis is essential for prognostication in chronic liver disease. This study aimed to evaluate the diagnostic performance of MRI in assessing liver fibrosis and steatosis in patients undergoing liver transplantation (LT).
Eun‐Ki Min +7 more
wiley +1 more source
3D numerical modelling and analysis of a magnetorheological elastomer (MRE) [PDF]
, 2020 Thaer M. I. Syam +3 more
openalex +1 more source
Soft MRE Gripper: Preliminary Study
Soft robotics focuses on the imitation of the work of living organisms and mostly utilizes soft deformable materials for actuation or object manipulation tasks. Soft robots or grippers can be used for tasks which are beyond the reach of conventional rigid body ones.
Denys Gutenko +3 more
openaire +1 more source