Results 21 to 30 of about 97,528 (241)

Environmentally responsive MRI contrast agents [PDF]

open access: yesChemical Communications, 2013
Biomedical imaging techniques can provide a vast amount of anatomical information, enabling diagnosis and the monitoring of disease and treatment profile. MRI uniquely offers convenient, non-invasive, high resolution tomographic imaging. A considerable amount of effort has been invested, across several decades, in the design of non toxic paramagnetic ...
Davies, G-L, Kramberger, I, Davis, JJ
openaire   +4 more sources

A novel MRI contrast agent synthesized by ion exchange method [PDF]

open access: yesNanomedicine Journal, 2018
Objective: In this study, the zeolite-coated iron oxide nanoparticles were evaluated as MRI contrast agent and effect of the nanocomposite synthesis method on MRI contrast was tested.
nahideh gharehaghaji, baharak divband
doaj   +1 more source

Research Progresses in Development of Thermo-Sensitive MRI Contrast Agent

open access: yesChinese Journal of Magnetic Resonance, 2018
Magnetic resonance imaging (MRI) is a practical technique for non-invasive temperature measurement. Thermo-sensitive MRI contrast agents, which cause temperature-dependent changes in magnetic resonance parameters of water molecules (i.e., relaxation ...
LU Yao, ZHENG Xin-wei, ZHONG Kai
doaj   +1 more source

MRI Contrast Agents for Pharmacological Research [PDF]

open access: yesFrontiers in Pharmacology, 2015
The advent of the molecular imaging era has offered to pharmacologists very powerful tools for drug discovery and development, in vivo evaluation of pharmacokinetic properties, and monitoring drug efficacy (Hargreaves, 2008; Nairne et al., 2015). In fact, molecular imaging technologies provide minimally invasive procedures to visualize, characterize ...
Terreno, Enzo, Aime, Silvio
openaire   +3 more sources

Viral capsids as MRI contrast agents [PDF]

open access: yesMagnetic Resonance in Medicine, 2007
AbstractViral capsids have the potential for combined cell/tissue targeting, drug delivery, and imaging. Described here is the development of a viral capsid as an efficient and potentially relevant MRI contrast agent. Two approaches are outlined to fuse high affinity Gd3+ chelating moieties to the surface of the cowpea chlorotic mottle virus (CCMV ...
Lars, Liepold   +6 more
openaire   +2 more sources

Targeted Contrast Agents for Molecular MRI

open access: yesInorganics, 2018
Molecular magnetic resonance imaging (MRI) provides information non-invasively at cellular and molecular levels, for both early diagnosis and monitoring therapeutic follow-up.
Sara Lacerda
doaj   +1 more source

Biocompatible Nanocomplexes for Molecular Targeted MRI Contrast Agent

open access: yesNanoscale Research Letters, 2009
Accurate diagnosis in early stage is vital for the treatment of Hepatocellular carcinoma. The aim of this study was to investigate the potential of poly lactic acid–polyethylene glycol/gadolinium–diethylenetriamine-pentaacetic acid (PLA–
Yu Dexin   +5 more
doaj   +1 more source

Dual-modal MRI T1-T2 Contrast Agent Based on Dynamic Organic Gadolinium Nanoparticles

open access: yesChinese Journal of Magnetic Resonance, 2022
In this work, a new magnetic resonance imaging (MRI) contrast agent based on organic gadolinium (Gd) nanoparticles was designed, synthesized and tested.
Ju-min ZHANG, Shi-zhen CHEN, Xin ZHOU
doaj   +1 more source

Iron(II) PARACEST MRI Contrast Agents [PDF]

open access: yesJournal of the American Chemical Society, 2011
The first examples of Fe(II) PARACEST magnetic resonance contrast agents are reported (PARACEST = paramagnetic chemical exchange saturation transfer). The iron(II) complexes contain a macrocyclic ligand, either 1,4,7-tris(carbamoylmethyl)-1,4,7-triazacyclononane (L1) or 1,4,7-tris[(5-amino-6-methyl-2-pyridyl)methyl]-1,4,7-triazacyclononane (L2).
Sarina J, Dorazio   +4 more
openaire   +2 more sources

Mesoporous Silica Nanoparticles with Co-Condensed Gadolinium Chelates for Multimodal Imaging

open access: yesNanomaterials, 2011
Several mesoporous silica nanoparticle (MSN) contrast agents have been synthesized using a co-condensation method to incorporate two different Gd3+ complexes at very high loadings (15.5–28.8 wt %).
Wenbin Lin   +2 more
doaj   +1 more source

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