Results 111 to 120 of about 78,373 (263)

Enhanced Degradation of Vinyl Copolymers Based on Lipoic Acid

open access: yesJournal of Polymer Science, Volume 63, Issue 6, Page 1345-1351, 15 March 2025.
ABSTRACT The introduction of degradable units into the backbone of commodity vinyl polymers represents a major opportunity to address the societal challenge of plastic waste and polymer recycling. Previously, we reported the facile copolymerization of α‐lipoic acid derivatives containing 1,2‐dithiolane rings with vinyl monomers leading to the ...
Yoichi Okayama   +7 more
wiley   +1 more source

Impact of Stabilizing Osmolytes on the Conformational Dynamics of Human and Rat Islet Amyloid Polypeptides

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The aggregation of human islet amyloid polypeptide (hIAPP) into cytotoxic oligomers and amyloid fibrils is a hallmark of type 2 diabetes mellitus (T2DM), leading to pancreatic β‐cell dysfunction. In contrast, rat IAPP (rIAPP) is largely non‐amyloidogenic. Osmolytes such as glucose, glycerol, and sorbitol are known to stabilize globular protein
Kiara A. Kidman   +3 more
wiley   +1 more source

Presence of Nationally Banned Carbamates and Organophosphate Pesticides in Wild Carnivores, Southeastern Brazil

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT As top predators, terrestrial carnivores face great risk of pesticide exposure and serve as sentinels of environmental contamination. Additionally, terrestrial carnivores are frequently threatened by intentional or secondary poisoning with highly toxic compounds, such as carbamates and organophosphates.
Marina Pellegrino da Silva   +10 more
wiley   +1 more source

The emergence of anti-dsDNA antibodies precedes nucleosome-specific antibodies in MRL/lpr and MRL/+ mice.

open access: yesJournal of medical and dental sciences, 2003
Nucleosome (NS)-reactive autoantibodies appear to be involved in the pathogenesis of systemic lupus erythematosus (SLE), but the mechanisms responsible for their production remain elusive. To study whether antibodies specific to NS are present prior to anti-double-stranded (ds) DNA antibodies in lupus mice, ELISA was carried out using the plates which ...
Qing Lu   +2 more
openaire   +2 more sources

Primordial power spectrum from Planck

open access: yes
Using modified Richardson-Lucy algorithm we reconstruct the primordial power spectrum (PPS) from Planck Cosmic Microwave Background (CMB) temperature anisotropy data.
Hazra, Dhiraj Kumar   +2 more
core   +2 more sources

Aptamer‐mediated outer membrane destabilization overcomes low permeability resistance in Pseudomonas aeruginosa

open access: yesThe FEBS Journal, EarlyView.
DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam   +4 more
wiley   +1 more source

Demonstration of a High‐Resolution Passive Profiler for Characterizing the Distribution of PFAS in Groundwater: A Comparison of Methods in the Field

open access: yesGroundwater Monitoring &Remediation, EarlyView.
Abstract Characterizing the concentration and mass flux spatial distributions at sites with complex hydrogeologic conditions is critical to evaluate the fate and transport of contaminants, as well as to design effective remediation programs. PFAS (per‐ and polyfluoroalkyl substances)‐contaminated sites are even more complex due to the large number of ...
Morgan Eldridge   +8 more
wiley   +1 more source

Disentangling direct and indirect genetic pathways to neurodevelopmental risk: brain structure and behavior in a population‐based parent–offspring trio study

open access: yesJournal of Child Psychology and Psychiatry, EarlyView.
Background Neurodevelopmental disorders (NDDs) are highly heritable, yet the pathways linking parental genetic liability to child outcomes remain poorly understood. Traditional designs cannot easily separate genes transmitted to the child from environmental influences shaped by parental genotypes.
Fin J. E. van Uum   +10 more
wiley   +1 more source

A phase 3, single-arm, open-label study to evaluate the safety, tolerability, and immunogenicity of a 15-valent pneumococcal conjugate vaccine, V114, in a 3+1 regimen in healthy infants in South Korea (PNEU-PED-KOR)

open access: yesHuman Vaccines & Immunotherapeutics
There is an ongoing burden of pneumococcal disease in children despite the use of pneumococcal conjugate vaccines (PCVs). This phase 3, open-label, single-arm, multisite, descriptive study was designed to evaluate the safety and immunogenicity of a 3 + 1
Alvino Maestri   +16 more
doaj   +1 more source

A generalization of periodic autoregressive models for seasonal time series [PDF]

open access: yes
Many nonstationary time series exhibit changes in the trend and seasonality structure, that may be modeled by splitting the time axis into different regimes. We propose multi-regime models where, inside each regime, the trend is linear and seasonality is
battaglia francesco   +2 more
core  

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