Results 21 to 30 of about 33,403 (259)

Evaluation of Pesticide Residues in Vegetables from the Asir Region, Saudi Arabia

open access: yesMolecules, 2020
This study’s aim was to determine the pesticide residues in 10 different vegetable commodities from the Asir region, Saudi Arabia. We evaluated 211 vegetable samples, collected from supermarkets between March 2018 and September 2018, for a total of
Mohamed F. A. Ramadan   +7 more
doaj   +1 more source

Tau-tubulin kinase 1 phosphorylates TDP-43 at disease-relevant sites and exacerbates TDP-43 pathology

open access: yesNeurobiology of Disease, 2021
TDP-43 pathology is a hallmark of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal lobar degeneration (FTLD). Namely, both diseases feature aggregated and phosphorylated TDP-43 containing inclusions in the cytoplasm and a loss of nuclear TDP-43 in ...
Yuan Tian   +9 more
doaj   +1 more source

Taste aversion learning in autoimmune MRL-lpr/lpr and Mrl +/+ mice

open access: yesBrain, Behavior, and Immunity, 1987
Conditioned taste aversion to a neutral stimulus paired with an immunosuppressive drug (cyclophosphamide) was assessed in lupus-prone MRL-lpr/lpr and congenic control (MRL +/+) mice. The presence of lymphoproliferation in MRL-lpr/lpr mice was associated with poorer taste aversion learning and varied as a function of the dose of cyclophosphamide.
L J, Grota, R, Ader, N, Cohen
openaire   +2 more sources

A novel approach to determine residual aldehyde content in conjugated polysaccharides with 3-methyl-2-benzothiazolinonehydrazon (MBTH) by colorimetric method, automation, and HP-SEC

open access: yesJournal of Pharmaceutical and Biomedical Analysis Open, 2023
Polysaccharide activation by periodate oxidation to form aldehydes, followed by conjugation with proteins via reductive amination is a general procedure to make polysaccharide-protein conjugate vaccines.
Weidong Tong   +4 more
doaj   +1 more source

Ceftolozane/tazobactam versus meropenem in patients with ventilated hospital-acquired bacterial pneumonia: subset analysis of the ASPECT-NP randomized, controlled phase 3 trial

open access: yesCritical Care, 2021
Background Ceftolozane/tazobactam is approved for treatment of hospital-acquired/ventilator-associated bacterial pneumonia (HABP/VABP) at double the dose approved for other infection sites.
Jean-François Timsit   +14 more
doaj   +1 more source

Evaluation of confirmatory data following the Article 12 MRL review for cycloxydim and modification of the existing MRLs for escaroles, land cresses and cresses. [PDF]

open access: yesEFSA J
Abstract The applicant BASF SE submitted a request to the competent national authority in the Netherlands to evaluate the confirmatory data for cycloxydim, which had been identified as unavailable in the framework of the maximum residue level (MRL) review under Article 12 of Regulation (EC) No 396/2005.
European Food Safety Authority (EFSA)   +11 more
europepmc   +2 more sources

Residues of Fluoroquinolone Antibiotics Induce Carbonylation and Reduce In Vitro Digestion of Sarcoplasmic and Myofibrillar Beef Proteins

open access: yesFoods, 2020
Although the impact of oxidation on human health has been of growing interest, the oxidation of proteins, major component of meat, has received little attention.
Johana Márquez-Lázaro   +2 more
doaj   +1 more source

BioPhi: A platform for antibody design, humanization, and humanness evaluation based on natural antibody repertoires and deep learning

open access: yesmAbs, 2022
Despite recent advances in transgenic animal models and display technologies, humanization of mouse sequences remains one of the main routes for therapeutic antibody development.
David Prihoda   +6 more
doaj   +1 more source

Genomic analysis of the appearance of testicular oocytes in MRL/MpJ mice [PDF]

open access: yes, 2012
Mammals produce sperm or oocytes depending on their sex; however, newborn MRL/MpJ (MRL) male mice produce oocytes within their testes. We previously reported that one of the genes responsible for this phenotype is present on the MRL-type Y chromosome (Y^[
Otsuka, Saori   +5 more
core   +1 more source

Sequential study of vasculitis in MRL mice [PDF]

open access: yesLaboratory Animals, 1987
The frequency, age of onset and organ distribution of spontaneously occurring vasculitis was examined in a sequential study with 170 MRL mice of both substrains. Necrotizing vasculitis was seen in 55·8% of MRL/Mp-lpr/lpr mice studied, beginning at the age of 3 months. The kidney and urinary bladder were most frequently involved.
M, Hewicker, G, Trautwein
openaire   +2 more sources

Home - About - Disclaimer - Privacy