Results 21 to 30 of about 77,587 (260)

Evaluation of Pesticide Residues in Vegetables from the Asir Region, Saudi Arabia

open access: yesMolecules, 2020
This study’s aim was to determine the pesticide residues in 10 different vegetable commodities from the Asir region, Saudi Arabia. We evaluated 211 vegetable samples, collected from supermarkets between March 2018 and September 2018, for a total of
Mohamed F. A. Ramadan   +7 more
doaj   +1 more source

A novel approach to determine residual aldehyde content in conjugated polysaccharides with 3-methyl-2-benzothiazolinonehydrazon (MBTH) by colorimetric method, automation, and HP-SEC

open access: yesJournal of Pharmaceutical and Biomedical Analysis Open, 2023
Polysaccharide activation by periodate oxidation to form aldehydes, followed by conjugation with proteins via reductive amination is a general procedure to make polysaccharide-protein conjugate vaccines.
Weidong Tong   +4 more
doaj   +1 more source

MRL-based Importance Measures [PDF]

open access: yesProceedings of the 29th European Safety and Reliability Conference (ESREL), 2019
In this paper, we propose a novel importance measure, namely LIM, which is defined as the improvement ability in the system residual life when replacing a component/group of components at a given time. LIM measure allows considering the current condition (state or degradation level) of all components at given time and the system structure into a single
Phuc Do   +2 more
openaire   +1 more source

Functionally inactivated dominant viral antigens of human cytomegalovirus delivered in replication incompetent adenovirus type 6 vectors as vaccine candidates

open access: yesHuman Vaccines & Immunotherapeutics, 2017
T cell immunity is critical in controlling human cytomegalovirus (HCMV) infection in transplant recipients, and T cells targeting viral immediate early proteins such as IE1, IE2 and pp65 have been speculated to be more effective against reactivation ...
Aimin Tang   +8 more
doaj   +1 more source

From Galaxy Clusters to Ultra-Faint Dwarf Spheroidals: A Fundamental Curve Connecting Dispersion-supported Galaxies to Their Dark Matter Halos [PDF]

open access: yes, 2010
We examine scaling relations of dispersion-supported galaxies over more than eight orders of magnitude in luminosity by transforming standard fundamental plane parameters into a space of mass (M1/2), radius (r1/2), and luminosity (L1/2).
Adelman-McCarthy   +83 more
core   +1 more source

Taste aversion learning in autoimmune MRL-lpr/lpr and Mrl +/+ mice

open access: yesBrain, Behavior, and Immunity, 1987
Conditioned taste aversion to a neutral stimulus paired with an immunosuppressive drug (cyclophosphamide) was assessed in lupus-prone MRL-lpr/lpr and congenic control (MRL +/+) mice. The presence of lymphoproliferation in MRL-lpr/lpr mice was associated with poorer taste aversion learning and varied as a function of the dose of cyclophosphamide.
L J, Grota, R, Ader, N, Cohen
openaire   +2 more sources

Antibody-drug conjugates: integrated bioanalytical and biodisposition assessments in lead optimization and selection

open access: yesAAPS Open, 2018
Therapies based on monoclonal antibodies (mAbs) have delivered an impressive success in the clinics due to their exquisite specificity, potential for agonistic or antagonistic responses, tunable effector function, and optimal pharmacokinetic properties ...
Maribel Beaumont   +27 more
doaj   +1 more source

Ceftolozane/tazobactam versus meropenem in patients with ventilated hospital-acquired bacterial pneumonia: subset analysis of the ASPECT-NP randomized, controlled phase 3 trial

open access: yesCritical Care, 2021
Background Ceftolozane/tazobactam is approved for treatment of hospital-acquired/ventilator-associated bacterial pneumonia (HABP/VABP) at double the dose approved for other infection sites.
Jean-François Timsit   +14 more
doaj   +1 more source

A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration. [PDF]

open access: yes, 2015
The leading edge of migrating cells contains rapidly translocating activated integrins associated with growing actin filaments that form 'sticky fingers' to sense extracellular matrix and guide cell migration.
Ablack, Jailal N   +6 more
core   +2 more sources

BioPhi: A platform for antibody design, humanization, and humanness evaluation based on natural antibody repertoires and deep learning

open access: yesmAbs, 2022
Despite recent advances in transgenic animal models and display technologies, humanization of mouse sequences remains one of the main routes for therapeutic antibody development.
David Prihoda   +6 more
doaj   +1 more source

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