Results 71 to 80 of about 33,403 (259)

Lipid Traffic Analysis reveals the impact of high paternal carbohydrate intake on offsprings’ lipid metabolism

open access: yesCommunications Biology, 2021
Furse et al. use a purpose-built computational tool called Lipid Traffic Analysis to determine the spatial distribution of lipids throughout an organism.
Samuel Furse   +6 more
doaj   +1 more source

Percentages of the different T-cell subsets in LNs from MRL+/+, MRL/lpr, B6 and B6/lpr mice.

open access: yes, 2012
*3 to 4-mo-old MRL+/+ and MRL/lpr mice, n represents the number of mice per group.**1½ to 2-mo-old MRL/lpr mice.***5-mo- old B6 and B6/lpr mice.
Hanaa Safya (108758)   +6 more
core   +1 more source

Physical Activity and Risk of Liver Cancer: A Competing Risk Analysis

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Physical activity is associated with lower risk of liver cancer, but obtaining an unbiased estimate of the causal effect is challenging due to the competing risk of death due to any other cause. We performed a causal competing risk analysis to estimate the total effect of physical activity on risk of liver cancer in the presence of competing ...
Frances E. M. Albers   +9 more
wiley   +1 more source

MRL as one-shot examination for patients suffering from lymphedema

open access: yes, 2020
MR lymphangiography (MRL) is an emerging technique focalized on a noninvasive or minimally invasive imaging of lymphatics with the goal to treat and plan lymphedema. Doctor Cellina M. and colleagues clearly underlined the possible role of MRL with volume
Mazzei M. A.   +4 more
core   +1 more source

MRL/MpJ-Fas(lpr) mice show abnormalities in ovarian function and morphology with the progression of autoimmune disease [PDF]

open access: yes, 2015
The immune system is known to affect reproductive function, and maternal-fetal immune tolerance is essential for a successful pregnancy. To investigate the relationship between autoimmune disease and female reproductive function, we performed a ...
Teppei Nakamura   +11 more
core   +1 more source

Epigenetic Predictors of Smoking: External Validation and Association With Smoking‐Related Cancer Risk

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Tobacco smoking has a strong influence on DNA methylation (DNAm), enabling the development of DNAm‐based smoking predictors, yet external evaluations of these have remained limited. We aimed to assess six DNAm‐based smoking predictors in a large sample of middle‐aged and older Australians for (i) their accuracy and reliability, and (ii) their ...
Xiaoyu Fan   +8 more
wiley   +1 more source

First-in-human safety and pharmacokinetics of MK-7602, the antimalarial inhibitor of plasmepsins IX/X, in single- and multiple-ascending-dose studies

open access: yesAntimicrobial Agents and Chemotherapy
MK-7602 is a first-in-class dual-plasmepsin inhibitor being developed to treat malaria. Safety, tolerability, and pharmacokinetics (PK) of MK-7602 following single and multiple doses were evaluated in two phase 1 studies (7602-001; 7602-002).
Susan E. Stanley   +16 more
doaj   +1 more source

Prospective Analysis of Breastfeeding History and Ovarian Cancer Risk: Results From the Ovarian Cancer Cohort Consortium

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Breastfeeding has been found to be associated with decreased ovarian cancer risk, but prospective analyses are sparse and limited by insufficient sample sizes to assess associations by histotype and patient characteristics. To investigate the association between breastfeeding (ever/never, duration, and timing) and incident epithelial ovarian ...
Sable N. Fest   +25 more
wiley   +1 more source

CellVision: A deep learning based image analysis platform to accelerate immuno-plaque assay data processing for dengue vaccine development

open access: yesSLAS Discovery
Accurately detecting patterns of interest across a large number of images presents a significant challenge in data analysis for high-throughput analytical assays.
Yi Wang   +8 more
doaj   +1 more source

Induction and Analysis of Anti-CD40-induced Colitis in Mice

open access: yesBio-Protocol, 2019
Colon inflammation or colitis affects more than 1 million people worldwide. Several pre-clinical models, including chemical-induced (i.e., DSS, TNBS) or pathogen-induced (i.e., Citrobacter rodentium) have been used to study mechanisms involved in the ...
Barbara Joyce-Shaikh   +2 more
doaj   +1 more source

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