Results 51 to 60 of about 33,403 (259)
IgG Glycosylation‐Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis
Arthritis &Rheumatology, EarlyView.Objective Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) that can lead to end‐stage kidney disease and increased mortality. IgG from patients with LN displays abnormal glycosylation, contributing to podocyte injury.
Rohit Upadhyay +3 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Virus‐like particles (VLPs) are a promising modality with extensive applications in prophylactic and therapeutic vaccine design. Human Papillomavirus (HPV) vaccines are one such example where VLP vaccine applications have led to the successful reduction in HPV‐associated diseases, such as cervical cancer.
Nicholas Samuelson +5 more
wiley +1 more source
Biostructural, biochemical and biophysical studies of mutant IDH1
Nature CommunicationsWe report bio-structural, bio-chemical and bio-physical evidence demonstrating how small molecules can bind to both wild-type and mutant IDH1, but only inhibit the enzymatic activity of the mutant isoform.
Mark A. McCoy +5 more
doaj +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Tangential flow filtration (TFF) is an essential operation in downstream bioprocessing, yet conventional scale‐down models require large material volumes and often fail to capture scale‐relevant hydrodynamics. A microfluidic TFF (µTFF) platform was developed that preserves wall shear rate and transmembrane pressure, enabling low‐volume ...
Nusrat Jahan +3 more
wiley +1 more source
Julius-Kühn-Archiv, 2020 A new study design, according to the guideline SANTE11956/2016 rev:9 (2018), was established to determine the maximum residue level (MRL) of plant protection products in honey.
Cohen, Yotam +3 more
doaj +1 more source
FEBS Letters, 2001 MRL mice bearing the lpr (Fas) or gld (Fas ligand) mutation, MRL‐Faslpr or MRL‐FasLgld , respectively, develop arthritis similar to rheumatoid arthritis, but C3H and C57BL/6 mice bearing such mutations do not. In MRL‐Faslpr mice, agalactosylated oligosaccharides in serum IgG increase significantly in comparison to MRL‐+/+ mice without arthritis.
Kuroda, Yasuhiro +4 more
openaire +2 more sources
, 2011 Copyright information:Taken from "Analysis of C4 and the C4 binding protein in the MRL/lpr mouse"http://arthritis-research.com/content/9/5/R114Arthritis Research & Therapy 2007;9(5):R114-R114.Published online 30 Oct 2007PMCID:PMC2212569.
Rick A Wetsel (39170) +3 more
core +1 more source
Graphene Materials for Sustainable Energy Applications: A Contemporary Perspective
Carbon Energy, EarlyView.ABSTRACT Graphene has garnered significant attention as a promising material with great potential for contributing to sustainable energy initiatives, such as RE100 (100% renewable energy initiative) and CF100 (100% carbon‐free initiative). This review aims to explore the potential of graphene for advancing renewable energy applications by highlighting
Niraj Kumar +3 more
wiley +1 more source
Hard Turning Performance Investigation of AISI D2 Steel under a Dual Nozzle MQL Environment
Lubricants, 2023 In recent years, hard turning has emerged as a burgeoning cutting technology for producing high-quality finishing of cylindrical-shaped hardened steel for a variety of industrial applications.
Rajashree Mallick +3 more
doaj +1 more source