Antibody Response After Third Vaccination With mRNA-1273 or BNT162b2: Extension of a Randomized Controlled SARS-CoV-2 Noninferiority Vaccine Trial in Patients With Different Levels of Immunosuppression (COVERALL-2) [PDF]
Extension of the COVERALL (COrona VaccinE tRiAL pLatform) randomized trial showed noninferiority in antibody response of the third dose of Moderna mRNA-1273 vaccine (95.3% [95% confidence interval {CI}, 91.9%-98.7%]) compared to Pfizer-BioNTech BNT162b2 ...
Abela, Irene A +25 more
core +1 more source
Comparative Effectiveness of BNT162b2 and mRNA-1273 Vaccines in U.S. Veterans
Background The messenger RNA (mRNA)–based vaccines BNT162b2 and mRNA-1273 are more than 90% effective against coronavirus disease 2019 (Covid-19). However, their comparative effectiveness for a range of outcomes across diverse populations is unknown ...
B. Dickerman +10 more
semanticscholar +1 more source
Comparison of mRNA Vaccinations with BNT162b2 or mRNA-1273 in Anti-CD20-Treated Multiple Sclerosis Patients [PDF]
Objective: Anti-CD20-treated patients are at risk of a reduced humoral immune response during the SARS-CoV-2 pandemic. Our aim was to compare the antibody response after two vaccinations with the mRNA vaccines BNT162b2 or mRNA-1273 in patients with ...
Chan, Andrew +9 more
core +1 more source
Background Patients with cancer have an increased risk of complications from SARS-CoV-2 infection. Vaccination to prevent COVID-19 is recommended, but data on the immunogenicity and safety of COVID-19 vaccines for patients with solid tumours receiving ...
S. Oosting +22 more
semanticscholar +1 more source
Induction of SARS-CoV-2-Specific IgG and IgA in Serum and Milk with Different SARS-CoV-2 Vaccines in Breastfeeding Women: A Cross-Sectional Study in Northern Spain [PDF]
Breastfeeding mothers were excluded from the clinical trials conducted for vaccines against SARS-CoV-2. Since the start of the vaccination, some doubts have arisen regarding its compatibility with breastfeeding.
Cabero Pérez, María Jesús +8 more
core +1 more source
Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates
Description Antibodies dovetail with protection Immune correlates of protection are clinical end points used to gauge vaccine-induced immunogenicity and protection. Corbett et al.
Kizzmekia S. Corbett +63 more
semanticscholar +1 more source
Background Heterologous prime-boost with ChAdOx1 nCoV-19 vector vaccine (ChAd) and a messenger RNA vaccine (BNT or mRNA-1273) has been widely facilitating mass coronavirus disease 2019 (COVID-19) immunisation.
Jingjing Lv +3 more
doaj +1 more source
Impact of immunosuppressive treatment and type of SARS-CoV-2 vaccine on antibody levels after three vaccinations in patients with chronic kidney disease or kidney replacement therapy [PDF]
Background. Patients with chronic kidney disease (CKD) or kidney replacement therapy demonstrate lower antibody levels after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination compared with healthy controls. In a prospective cohort,
+16 more
core +1 more source
Prevention and Attenuation of Covid-19 with the BNT162b2 and mRNA-1273 Vaccines
BACKGROUND: Information is limited regarding the effectiveness of the two-dose messenger RNA (mRNA) vaccines BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna) in preventing infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and ...
M. Thompson +56 more
semanticscholar +1 more source
Introdução: A vacinação continua sendo crucial para a proteção contra a infecção grave pelo SARS-CoV-2, especialmente na população idosa. Métodos: Avaliamos, em um estudo de fase II randomizado, controlado, adaptativo e multicêntrico, a segurança e a ...
Jon Salmanton-Garcia +7 more
doaj +1 more source

