Results 41 to 50 of about 839,337 (241)

Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

Science, 2021
Description A boost for boosters The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern poses a potential obstacle to achieving vaccine-induced immunity. Pegu et al.
A. Pegu, S. O'connell, S. Schmidt, S. O'Dell, C. A. Talana, L. Lai, J. Albert, E. Anderson, H. Bennett, Kizzmekia S. Corbett, B. Flach, L. Jackson, B. Leav, J. Ledgerwood, C. Luke, M. Makowski, M. Nason, P. Roberts, M. Roederer, P. Rebolledo, C. Rostad, N. Rouphael, W. Shi, Lingshu Wang, A. Widge, E. Yang, J. Beigel, B. Graham, J. Mascola, M. Suthar, A. McDermott, N. Doria-Rose   +31 more
semanticscholar   +1 more source

Comparative analysis of COVID-19 vaccine responses and third booster dose-induced neutralizing antibodies against Delta and Omicron variants [PDF]

, 2022
Vaccination shows efficacy in protecting from COVID-19, but regime and dosing optimization is still ongoing. Here the authors show that BNT162b2, mRNA-1273, or their combination with ChAdOx1 induces similar antibody responses, and those receiving three ...
Belik, Milja, Häkkinen, Hanni K., Ivaska, Lauri, Jalkanen, Pinja, Julkunen, Ilkka, Kakkola, Laura, Kantele, Anu, Kolehmainen, Pekka, Laine, Larissa, Lempainen, Johanna, Lundberg, Rickard, Miettinen, Simo, Naves, Rauno A., Ortamo, Eeva, Pakkanen, Sari H., Pasternack, Arja, Reinholm, Arttu, Ritvos, Mikael A., Ritvos, Olli, Sironen, Tarja, Skön, Marika, Tahtinen, Paula A., Vapalahti, Olli, Väisänen, Elina, Österlund, Pamela   +24 more
core   +1 more source

Humeral and cellular immune responses to SARS-CoV-2 vaccination in patients on peritoneal dialysis

Journal of the Formosan Medical Association, 2023
Background: Patients with chronic kidney disease are at high risk for coronavirus disease 2019. Little is known about immune response to severe acute respiratory syndrome coronavirus 2 vaccination in patients on peritoneal dialysis (PD).
Zhi-Ye Yu, Chun-Fu Lai, Tai-Shuan Lai, Shao-Yu Yang, Shih-I Chen, Mei-Jun Lai, Chun-Min Kang, Yu-Tsung Huang, Yi-Ting Chen, Po-Ren Hsueh, Yung-Ming Chen, Shuei-Liong Lin   +11 more
doaj   +1 more source

The effectiveness of mRNA vaccines to prevent SARS-CoV-2 infection and hospitalisation for COVID-19 according to the time elapsed since their administration in health professionals in the Valencian Autonomous Community (Spain) [PDF]

, 2022
The objective was to understand the effectiveness of the BNT162b2 and mRNA-1273 vaccines against SARS-CoV-2 in health professionals(HPs) in the Valencian Autonomous Community(Spain) who had completed a full vaccination regimen, both in terms of ...
Algado-Sellés, Natividad, Berenguer, Ana, Burgos, Javier S., Chico-Sánchez, Pablo, Gras-Valentí, Paula, Jiménez-Sepúlveda, Natali Juliet, Navarro, David, Peiró, Salvador, Sánchez-Payá, José, Vanaclocha Luna, Hermelinda   +9 more
core   +2 more sources

Comparative 6-Month Wild-Type and Delta-Variant Antibody Levels and Surrogate Neutralization for Adults Vaccinated with BNT162b2 versus mRNA-1273

Microbiology Spectrum, 2022
While mRNA vaccines are highly efficacious against short-term COVID-19, long-term immunogenicity is less clear. We compared humoral immunogenicity between BNT162b2 and mRNA-1273 vaccines 6 months after the first vaccine dose, examining the wild-type ...
Brian Grunau, Liam Golding, Martin A. Prusinkiewicz, Michael Asamoah-Boaheng, Richard Armour, Ana Citlali Marquez, Agatha N. Jassem, Vilte Barakauskas, Sheila F. O’Brien, Steven J. Drews, Scott Haig, Pascal M. Lavoie, David M. Goldfarb   +12 more
doaj   +1 more source

Evaluation of mRNA-1273 Covid-19 Vaccine in Children 6 to 11 Years of Age

New England Journal of Medicine, 2022
Background Vaccination of children to prevent coronavirus disease 2019 (Covid-19) is an urgent public health need. The safety, immunogenicity, and efficacy of the mRNA-1273 vaccine in children 6 to 11 years of age are unknown.
C. Creech, E. Anderson, V. Berthaud, I. Yildirim, A. Atz, Ivan Melendez Baez, Daniel Finkelstein, P. Pickrell, Judith Kirstein, C. Yut, Ronald Blair, R. Clifford, Michael Dunn, J. Campbell, D. Montefiori, J. Tomassini, Xiaoping Zhao, W. Deng, Honghong Zhou, Daniela Ramirez Schrempp, K. Hautzinger, B. Girard, K. Slobod, R. McPhee, R. Pajon, R. Das, Jacqueline M. Miller, S. Schnyder Ghamloush   +27 more
semanticscholar   +1 more source

Antibody Response Induced by BNT162b2 and mRNA-1273 Vaccines against the SARS-CoV-2 in a Cohort of Healthcare Workers [PDF]

, 2022
The aim of this study was to characterize the antibody response induced by SARS-CoV-2 mRNA vaccines in a cohort of healthcare workers. A total of 2247 serum samples were analyzed using the Elecsys(®) Anti-SARS-CoV-2 S-test (Roche Diagnostics ...
Amengual Guedan, Maria Jose, Berenguer-Llergo, Antoni, Calvet, Joan, Delgado, Juan Francisco, Espasa, Mateu, Gratacós, Jordi, Julià, Germà, Navarro Rubio, Gemma, Navarro, Marta, Peña, Pilar, Rodríguez, Sara, Serrano, Rosa M., Sánchez, Noemí, Van Den Eynde, Eva   +13 more
core   +1 more source

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

New England Journal of Medicine, 2020
Background Vaccines to prevent coronavirus disease 2019 (Covid-19) are urgently needed. The effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines on viral replication in both upper and lower airways is important to evaluate in ...
Kizzmekia S. Corbett, Barbara Flynn, K. Foulds, J. Francica, Seyhan Boyoglu-Barnum, Anne P. Werner, B. Flach, S. O'connell, Kevin W. Bock, Mahnaz Minai, Bianca M. Nagata, H. Anderson, David R. Martinez, Amy T. Noe, Naomi R. Douek, M. Donaldson, Nadesh N. Nji, Gabriela Alvarado, D. Edwards, Dillon R. Flebbe, Evan Lamb, N. Doria-Rose, Bob C. Lin, M. Louder, S. O'Dell, S. Schmidt, Emily Phung, Lauren A. Chang, Christina Yap, J. Todd, Laurent Pessaint, Alex Van Ry, Shanai Browne, J. Greenhouse, Tammy Putman-Taylor, Amanda Strasbaugh, Tracey-Ann Campbell, Anthony Cook, A. Dodson, Katelyn Steingrebe, W. Shi, Yi Zhang, O. Abiona, Lingshu Wang, A. Pegu, E. Yang, K. Leung, T. Zhou, I-Ting Teng, A. Widge, Ingelise J. Gordon, L. Novik, Rebecca A. Gillespie, Rebecca J. Loomis, Juan I. Moliva, Guillaume B. E. Stewart-Jones, Sunny Himansu, W. Kong, M. Nason, Kaitlyn M. Morabito, T. Ruckwardt, J. Ledgerwood, M. Gaudinski, P. Kwong, J. Mascola, A. Carfi, M. Lewis, R. Baric, A. McDermott, Ian N. Moore, N. Sullivan, M. Roederer, R. Seder, B. Graham   +73 more
semanticscholar   +1 more source

Low-dose mRNA-1273 COVID-19 vaccine generates durable memory enhanced by cross-reactive T cells

Science, 2021
Description A smaller-dose jab does the job Low-dose messenger RNA (mRNA) vaccines potentially allow health providers to administer more doses from a limited vaccine supply and can be less reactogenic.
J. Mateus, J. Dan, Zeli Zhang, C. Rydyznski Moderbacher, M. Lammers, B. Goodwin, A. Sette, S. Crotty, D. Weiskopf   +8 more
semanticscholar   +1 more source

Antibody response after a third dose mRNA-1273 vaccine among vaccinated healthcare workers with two doses of inactivated SARS-CoV-2 vaccine

International Journal of Infectious Diseases, 2022
Background: Health care workers (HCWs), a high-risk group for contracting COVID-19 disease, are being prioritized to receive COVID-19 vaccination. A third dose messenger RNA (mRNA) vaccine, mRNA-1273 (Moderna), after 2 doses of inactivated vaccine ...
Cucunawangsih Cucunawangsih, Ratna Sari Wijaya, Nata Pratama Hardjo Lugito, Ivet Suriapranata   +3 more
doaj   +1 more source