Results 81 to 90 of about 839,337 (241)

Comparative Effectiveness of BNT162b2 and mRNA-1273 Vaccines in U.S. Veterans

open access: yesNew England Journal of Medicine, 2021
Background The messenger RNA (mRNA)–based vaccines BNT162b2 and mRNA-1273 are more than 90% effective against coronavirus disease 2019 (Covid-19). However, their comparative effectiveness for a range of outcomes across diverse populations is unknown ...
B. Dickerman   +10 more
semanticscholar   +1 more source

Hybrid versus vaccine immunity of mRNA-1273 among people living with HIV in East and Southern Africa: a prospective cohort analysis from the multicentre CoVPN 3008 (Ubuntu) study. [PDF]

open access: goldEClinicalMedicine
Garrett N   +80 more
europepmc   +2 more sources

Sudden Sensorineural Hearing Loss Following Immunization With BNT162b2 or mRNA-1273:A Danish Population-Based Cohort Study [PDF]

open access: yes, 2023
Objective: To compare the occurrence of sudden sensorineural hearing loss following immunization with BNT162b2 (Comirnaty®; Pfizer BioNTech) or mRNA-1273 (Spikevax®; Moderna) to the occurrence among unvaccinated individuals.
Cleary, Brian   +6 more
core   +1 more source

Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates

open access: yesScience, 2021
Description Antibodies dovetail with protection Immune correlates of protection are clinical end points used to gauge vaccine-induced immunogenicity and protection. Corbett et al.
Kizzmekia S. Corbett   +63 more
semanticscholar   +1 more source

Interim analysis of a phase 1 randomized clinical trial on the safety and immunogenicity of the mRNA-1283 SARS-CoV-2 vaccine in adults

open access: yesHuman Vaccines & Immunotherapeutics, 2023
This interim analysis of an ongoing phase 1 randomized clinical trial evaluated the safety, reactogenicity, and immunogenicity of mRNA-1283, a next-generation SARS-CoV-2 messenger RNA (mRNA)-based vaccine encoding two segments of the spike protein (i.e ...
Patrick Yassini   +6 more
doaj   +1 more source

Comparing the human milk antibody response after vaccination with four COVID-19 vaccines:A prospective, longitudinal cohort study in the Netherlands [PDF]

open access: yes, 2022
Background: Vaccination of lactating women against COVID-19 may protect not only themselves but also their breastfed infant through human milk. Therefore, it is important to gain insight into the human milk antibody response after immunization with the ...
Bakker, S.   +15 more
core   +1 more source

Prevention and Attenuation of Covid-19 with the BNT162b2 and mRNA-1273 Vaccines

open access: yesNew England Journal of Medicine, 2021
BACKGROUND: Information is limited regarding the effectiveness of the two-dose messenger RNA (mRNA) vaccines BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna) in preventing infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and ...
M. Thompson   +56 more
semanticscholar   +1 more source

Relationship between immune response to SARS-CoV2 vaccines and development of breakthrough infection in solid organ transplant recipients: the CONTRAST cohort [PDF]

open access: yes, 2023
Background: SARS-CoV-2 vaccination in solid organ transplant (SOT) is associated with poorer antibody response (AbR) compared to non-SOT recipients. However, its impact on the risk of breakthrough infection (BI) should yet be assessed.
Bonazzetti, Cecilia   +21 more
core   +1 more source

Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection

open access: yesScience Translational Medicine, 2021
Deep mutational scanning shows that the mRNA-1273 RBD-binding antibody response is less affected by single viral mutations than the infection response.
Allison J. Greaney   +7 more
semanticscholar   +1 more source

Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Trial

open access: yesmedRxiv, 2021
Background: In the Coronavirus Efficacy (COVE) trial, estimated mRNA-1273 vaccine efficacy against coronavirus disease-19 (COVID-19) was 94%. SARS-CoV-2 antibody measurements were assessed as correlates of COVID-19 risk and as correlates of protection ...
P. Gilbert   +40 more
semanticscholar   +1 more source

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