Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal+8 more
wiley +1 more source
Musashi-dependent mRNA translational activation is mediated through association with the Scd6/Like-sm family member, LSM14B. [PDF]
Bronson K+7 more
europepmc +1 more source
Immunoglobulin light chain mRNA is processed from large nuclear RNA. [PDF]
Maureen Gilmore-Hebert, Randolph Wall
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An mRNA-based seasonal influenza vaccine in adults: Results of two phase 3 randomized clinical trials and correlate of protection analysis of hemagglutination inhibition titers. [PDF]
Kandinov B+22 more
europepmc +1 more source
Identification of mRNAs encoding the alpha and beta subunits of human choriogonadotropin.
Susan Daniels-McQueen+5 more
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Abstract Objectives An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation in Parkinson's disease and to evaluate the biomarker potential of methylation‐based ...
Ingeborg Haugesag Lie+4 more
wiley +1 more source
Less is more: slow-codon windows enhance eGFP mRNA resilience against RNA interference. [PDF]
Müller JA+6 more
europepmc +1 more source
Unleashing the Power of Multiomics: Unraveling the Molecular Landscape of Peripheral Neuropathy
ABSTRACT Peripheral neuropathies (PNs) affect over 20 million individuals in the United States, manifesting as a wide range of sensory, motor, and autonomic nerve symptoms. While various conditions such as diabetes, metabolic disorders, trauma, autoimmune disease, and chemotherapy‐induced neurotoxicity have been linked to PN, approximately one‐third of
Julie Choi+7 more
wiley +1 more source
Coupling mechanisms coordinating mRNA translation with stages of the mRNA lifecycle. [PDF]
Famà V+6 more
europepmc +1 more source
Decreased levels of collagen mRNA in rous sarcoma virus-transformed chick embryo fibroblasts
Bruce H. Howard+4 more
openalex +1 more source