Results 231 to 240 of about 2,344,135 (339)

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

Musashi-dependent mRNA translational activation is mediated through association with the Scd6/Like-sm family member, LSM14B. [PDF]

open access: yesSci Rep
Bronson K   +7 more
europepmc   +1 more source

An mRNA-based seasonal influenza vaccine in adults: Results of two phase 3 randomized clinical trials and correlate of protection analysis of hemagglutination inhibition titers. [PDF]

open access: yesHum Vaccin Immunother
Kandinov B   +22 more
europepmc   +1 more source

Identification of mRNAs encoding the alpha and beta subunits of human choriogonadotropin.

open access: hybrid, 1978
Susan Daniels-McQueen   +5 more
openalex   +1 more source

Epigenome‐wide association study, meta‐analysis, and multiscore profiling of whole blood in Parkinson's disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objectives An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation in Parkinson's disease and to evaluate the biomarker potential of methylation‐based ...
Ingeborg Haugesag Lie   +4 more
wiley   +1 more source

Less is more: slow-codon windows enhance eGFP mRNA resilience against RNA interference. [PDF]

open access: yesJ R Soc Interface
Müller JA   +6 more
europepmc   +1 more source

Unleashing the Power of Multiomics: Unraveling the Molecular Landscape of Peripheral Neuropathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Peripheral neuropathies (PNs) affect over 20 million individuals in the United States, manifesting as a wide range of sensory, motor, and autonomic nerve symptoms. While various conditions such as diabetes, metabolic disorders, trauma, autoimmune disease, and chemotherapy‐induced neurotoxicity have been linked to PN, approximately one‐third of
Julie Choi   +7 more
wiley   +1 more source

Coupling mechanisms coordinating mRNA translation with stages of the mRNA lifecycle. [PDF]

open access: yesRNA Biol
Famà V   +6 more
europepmc   +1 more source

Decreased levels of collagen mRNA in rous sarcoma virus-transformed chick embryo fibroblasts

open access: hybrid, 1978
Bruce H. Howard   +4 more
openalex   +1 more source

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