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Construction and Immunological Evaluation of a Bicomponent Zika mRNA Vaccine. [PDF]

open access: yesVaccines (Basel)
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mRNA turnover

Current Opinion in Cell Biology, 2001
Nuclear RNA-binding proteins can record pre-mRNA processing events in the structure of messenger ribonucleoprotein particles (mRNPs). During initial rounds of translation, the mature mRNP structure is established and is monitored by mRNA surveillance systems. Competition for the cap structure links translation and subsequent mRNA degradation, which may
P, Mitchell, D, Tollervey
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RIBONUCLEOPROTEIN PARTICLES CONTAINING mRNA and pre-mRNA

Acta Endocrinologica, 1973
ABSTRACT This paper is a review of the data concerning the nature, structural organization, properties and biological significance of the particles, containing mRNA and pre-mRNA (precursor of mRNA), i. e., (1) nuclear pre-mRNA-containing particles (2) free cytoplasmic mRNP (ribonucleoproteins), or informosomes (3) polysome-bound mRNP.
O P, Samarina   +2 more
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Pre-mRNA processing and mRNA nuclear export

Current Opinion in Cell Biology, 1989
The primary transcript of a prokaryotic gene is translated immediately following or during synthesis, whereas in eukaryotes, messenger RNA (mRNA) precursors (premRNAs) are synthesized in the nucleus and are then structurally altered and relocated to the cytoplasm before translation (Fig. 1).
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