Results 261 to 270 of about 1,902,766 (313)

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

CpG 1018 augments mRNA vaccine-induced anti-tumor immunity by potentiating CD8+ T cell responses. [PDF]

Mol Ther Oncol
Li Y, Nakkala JR, Akter L, Kang X, Song Y, VanLuinen E, Chen X.   +6 more
europepmc   +1 more source

APOBEC3A is the predominant global editor of cytosines in human mRNAs and in single-strand RNA viruses. [PDF]

G3 (Bethesda)
Kockler ZW, Bostan H, Klimczak LJ, Hsiao YC, Dennen MS, Cook ME, Mertz TM, Perelygina L, Kazanov MD, Li JL, Roberts SA, Gordenin DA.   +11 more
europepmc   +1 more source

Rapid assessment of immune effector cell-mediated cytotoxicity using mRNA lipid nanoparticles. [PDF]

Front Immunol
Mollica P, Li J, Kim SH, Goncalves B, Chen Y, Bharti A, O'Neill D, Weber E, Alameh M, Ma L.   +9 more
europepmc   +1 more source

ETV4 Improves Cerebral Ischemia-Reperfusion Injury by Restraining YBX1-GPX4-Ferroptosis Cascades. [PDF]

Brain Behav
Xu Q, Deng F, Yu D.
europepmc   +1 more source

Long-Term Durability and Dynamics of Anti-S-RBD IgG Response in Healthcare Workers: A Comparative Analysis of Homologous and Heterologous SARS-CoV-2 Vaccination Schedules in a 1-Year Serial Cross-Sectional Study. [PDF]

Med Sci Monit
Demirel Ç, Kibar F, Dağlıoğlu G, Çetiner S, Candevir A, İnal AS, Yücel Karakaya SP, Görüroğlu Öztürk Ö, Gümüş HH, İnal TC.   +9 more
europepmc   +1 more source

GPSM2 Promotes Pancreatic Cancer Progression Through METTL3-Mediated m6A Modification of YAP1 mRNA. [PDF]

J Cell Mol Med
Xiu J, Qiao L, Li M, Hu X, Shen Z, Yang R, Zhang H, Dong Z, Liu X, Zhang Y.   +9 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

mRNA turnover

Current Opinion in Cell Biology, 2001
Nuclear RNA-binding proteins can record pre-mRNA processing events in the structure of messenger ribonucleoprotein particles (mRNPs). During initial rounds of translation, the mature mRNP structure is established and is monitored by mRNA surveillance systems. Competition for the cap structure links translation and subsequent mRNA degradation, which may
P, Mitchell, D, Tollervey
openaire   +2 more sources

RIBONUCLEOPROTEIN PARTICLES CONTAINING mRNA and pre-mRNA

Acta Endocrinologica, 1973
ABSTRACT This paper is a review of the data concerning the nature, structural organization, properties and biological significance of the particles, containing mRNA and pre-mRNA (precursor of mRNA), i. e., (1) nuclear pre-mRNA-containing particles (2) free cytoplasmic mRNP (ribonucleoproteins), or informosomes (3) polysome-bound mRNP.
O P, Samarina, E M, Lukanidin, G P, Georgiev   +2 more
openaire   +2 more sources