Results 271 to 280 of about 1,902,766 (313)
Some of the next articles are maybe not open access.
2014
Uridine addition at the 3' end of RNAs (i.e., uridylation) emerges as a critical posttranscriptional modification promoting RNA degradation. Uridylation has been notably linked to the degradation of small RNAs, correlated with the 5' shortening of RISC-cleaved transcripts and the degradation of mRNAs.
Sement, F.M., Gagliardi, D.
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Uridine addition at the 3' end of RNAs (i.e., uridylation) emerges as a critical posttranscriptional modification promoting RNA degradation. Uridylation has been notably linked to the degradation of small RNAs, correlated with the 5' shortening of RISC-cleaved transcripts and the degradation of mRNAs.
Sement, F.M., Gagliardi, D.
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Pre-mRNA processing and mRNA nuclear export
Current Opinion in Cell Biology, 1989The primary transcript of a prokaryotic gene is translated immediately following or during synthesis, whereas in eukaryotes, messenger RNA (mRNA) precursors (premRNAs) are synthesized in the nucleus and are then structurally altered and relocated to the cytoplasm before translation (Fig. 1).
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Hybridization of mRNA and pre-mRNA with the sequences forming double-stranded structures in pre-mRNA
Molecular Biology Reports, 1973About 25% of the double-stranded sequences isolated from pre-mRNA are able to hybridize, after melting, with either mRNA or non-melted pre-mRNA. The retention of one branch of pre-mRNA hairpin in mRNA was suggested. It was also found that in addition to the hairpin-like structures comprising about 3% of the total sequences another 15% of the pre-mRNA ...
A P, Ryskov +2 more
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CYP3A5 mRNA Degradation by Nonsense-Mediated mRNA Decay
Molecular Pharmacology, 2005The total CYP3A5 mRNA level is significantly greater in carriers of the CYP3A5*1 allele than in CYP3A5*3 homozygotes. Most of the CYP3A5*3 mRNA includes an intronic sequence (exon 3B) containing premature termination codons (PTCs) between exons 3 and 4.
Florent, Busi, Thierry, Cresteil
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WIREs RNA, 2011
AbstractStudies in the past several years highlight important features of the messenger RNA (mRNA) export process. For instance, groups of mRNAs acting in the same biochemical processes can be retained or exported in a coordinated manner thereby impacting on specific biochemistries and ultimately on cell physiology.
Nadeem, Siddiqui, Katherine L B, Borden
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AbstractStudies in the past several years highlight important features of the messenger RNA (mRNA) export process. For instance, groups of mRNAs acting in the same biochemical processes can be retained or exported in a coordinated manner thereby impacting on specific biochemistries and ultimately on cell physiology.
Nadeem, Siddiqui, Katherine L B, Borden
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On the secondary structure in mRNA
Biosystems, 1977Abstract The sequence present in DNA phase transcripts have been investigated by Niyogi (1973) using a technique in which mRNA is enzymatically digested to yield different size classes that are resolved chromatographically into populations of equal chain lengths.
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Lipid nanoparticles for mRNA delivery
Nature Reviews Materials, 2021Xucheng Hou, Tal Zaks, Robert Langer
exaly