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Ribosome stalling-induced NIP5;1 mRNA decay triggers ARGONAUTE1-dependent transcription downregulation. [PDF]

open access: yesNucleic Acids Res
Tanaka M   +8 more
europepmc   +1 more source
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The highways and byways of mRNA decay

Nature Reviews Molecular Cell Biology, 2007
Nicole Garneau, J. Wilusz, C. Wilusz
semanticscholar   +3 more sources

Translation and mRNA decay

Molecular and General Genetics MGG, 1978
Degradation of messenger RNA from the lactose operon (lac mRNA) was measured during the inhibition of protein synthesis by chloramphenicol (CM) or of translation-initiation by kasugamycin (KAS). With increasing CM concentration mRNA decay becomes slower, but there is no direct proportionality between rates of chemical decay and polypeptide synthesis ...
E, Schneider, M, Blundell, D, Kennell
openaire   +2 more sources

Nonsense-mediated mRNA decay

Biochemical Society Transactions, 2008
Translation and mRNA decay are coupled processes; the link is most obvious in the case of NMD (nonsense-mediated mRNA decay). NMD is a mechanism that drastically reduces the level of mRNA harbouring PTCs (premature translation termination codons). The defining event in NMD is premature translation termination and the key question is: what distinguishes
Jikai, Wen, Saverio, Brogna
openaire   +2 more sources

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