Results 211 to 220 of about 87,391 (262)

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

Developmental Dynamics, EarlyView.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source

Regulation of co-translational mRNA decay by PAP and DXO1 in Arabidopsis. [PDF]

BMC Plant Biol
Carpentier MC, Receveur AE, Cadoudal A, Merret R.   +3 more
europepmc   +1 more source

Zebrafish inversin mutants develop scoliosis in the absence of laterality defects

Developmental Dynamics, EarlyView.
Abstract Background Human mutations in INVERSIN are associated with nephronophthisis, variable penetrance of situs inversus and congenital heart disease. Inversin has been shown to localize to cilia and many of the patient phenotypes are attributed to disrupted cilia function.
Christopher J. Derrick, Lorraine Eley, Deborah J. Henderson, Bill Chaudhry   +3 more
wiley   +1 more source

Predicting nonsense-mediated mRNA decay from splicing events in sepsis using RNA-sequencing data. [PDF]

Life Sci Alliance
Shin J, Fredericks AM, Armstead BE, Ayala A, Cohen M, Fairbrother WG, Levy MM, Lillard KK, Raggi E, Nau GJ, Monaghan SF.   +10 more
europepmc   +1 more source

An accessible microfluidic perfusion platform for time‐restricted control of zebrafish embryonic patterning

Developmental Dynamics, EarlyView.
Abstract Understanding the dynamic nature of developmental networks requires live imaging techniques capable of capturing real‐time developmental processes in wild‐type and mutant embryos as they are exposed to pharmacological perturbations. A peculiar developmental patterning process in early vertebrate embryos is the sequential segmentation of ...
Mohammed Nakhuda, M. Fethullah Simsek
wiley   +1 more source

Exploring the therapeutic potential of modulating nonsense-mediated mRNA decay. [PDF]

RNA
McMahon M, Maquat LE.
europepmc   +1 more source

A novel frameshift <i>STAG1</i> variant exhibiting haploinsufficiency due to the nonsense-mediated mRNA decay: a case report and literature review. [PDF]

Front Pediatr
Jiang C, Wu K, Zhou Y.
europepmc   +1 more source

<i>Smg5</i> Enhances Oligodendrocyte Differentiation via Nonsense-Mediated mRNA Decay of <i>Hnrnpl</i> Variant Transcripts. [PDF]

J Neurosci
Jiang M, Li C, Xie B, Li T, Dai ZM, Qiu M.   +5 more
europepmc   +1 more source

Proper 5'-3' cotranslational mRNA decay in yeast requires import of Xrn1 to the nucleus. [PDF]

PLoS One
Jordán-Pla A, Zhang Y, García-Martínez J, Chattopadhyay S, Forte A, Choder M, Pelechano V, Pérez-Ortín JE.   +7 more
europepmc   +1 more source