Results 61 to 70 of about 2,221,278 (207)

Gene Expression and the Physiological Role of Transforming Growth Factor-α in the Mouse Pituitary [PDF]

, 2003
Transforming growth factor-alpha (TGF-alpha), a member of the epidermal growth factor (EGF) family, is produced within the mouse anterior pituitaries. However, the cell types of TGF-alpha-expressing cells and the physiological roles of TGF-a within mouse
Kakeya, Tomoshi, Masui, Tohru, Oomizu, Souichi, Sharma, Seema, Takahashi, Sumio, Takeuchi, Sakae   +5 more
core   +1 more source

Quantitative mRNA expression measurement at home

Scientific Reports
AbstractmRNA measurement is dominated by RT-PCR, which requires expensive laboratory equipment and personnel with advanced degrees. Loop-mediated isothermal amplification (LAMP) is a versatile technique for detecting target DNA and RNA. The sensitivity of LAMP in early reports has been below that of the standard RT-PCR tests. Here, we report the use of
Pandey, Sonalisa, McCoy, Sara Safa, Stobdan, Tsering, Sahoo, Debashis   +3 more
openaire   +5 more sources

Factors determining in vitro survival of human multiple myeloma cells

Клиническая онкогематология, 2014
In this work, we investigated the survival of the human MM cell lines, i.e. RPMI1640, RPMI8226, and IM9, depending on the degree of their differentiation and impact of exogenous IGF-1.
S. S. Shushanov, T. A. Kravtsova, Yu. B. Cherhykh   +2 more
doaj   +1 more source

The Stargazin-Related Protein {gamma}7 Interacts with the mRNA-Binding Protein Heterogeneous Nuclear Ribonucleoprotein A2 and Regulates the Stability of Specific mRNAs, Including CaV2.2 [PDF]

, 2008
The role(s) of the novel stargazin-like {gamma}-subunit proteins remain controversial. We have shown previously that the neuron-specific {gamma}7 suppresses the expression of certain calcium channels, particularly CaV2.2, and is therefore unlikely to ...
Bolsover, Steven, Butcher, Adrian J., Cox, David J., Davies, Anthony, Dolphin, Annette C., Ferron, Laurent, Leroy, Jerôme, Moss, Fraser J., Page, Karen M., Pratt, Wendy S., Sellaturay, Priya, Waithe, Dominic   +11 more
core   +1 more source

Adverse prognostic and predictive significance of low DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in early-stage breast cancers [PDF]

, 2014
Background: DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a serine threonine kinase belonging to the PIKK family (phosphoinositide 3-kinase-like-family of protein kinase), is a critical component of the non-homologous end joining (NHEJ ...
AC Wolff, Andrew R. Green, Arvind Arora, B Salles, C Curtis, Christina Perry, Devika Agarwal, Emad Rakha, ET Shinohara, FM Hsu, Graham Ball, HS Lee, HS Lee, Ian O. Ellis, JA Neal, K Meek, K Soderlund Leifler, L Du, LA Loeb, LA Loeb, LM McShane, M Burg van der, Nicola Thompson, Paul Moseley, R Hill, R Sultana, S Medunjanin, SJ Collis, SL Shao, Srinivasan Madhusudan, Stephen Chan, SY Wang, Tarek Abdel-Fatah, TM Abdel-Fatah, TM Abdel-Fatah, TM Abdel-Fatah, U Moll, W Zhuang, X Kong, X Wang, XD Long, Z Hu   +41 more
core   +1 more source

Gene Regulation through mRNA Expression

Advances in Biological Chemistry, 2015
In eukaryotes, gene expression is achieved by four steps: transcription, processing, nuclear export, and translation. Each step requires multiple factors, and frequently two or more pathways are used by a single gene, enabling strictly regulated gene expression.
Haruko Inose, Kotomi Mukai, Misa Ito, Seiji Masuda   +3 more
openaire   +2 more sources

Distribution of α7 Nicotinic Acetylcholine Receptor Subunit mRNA in the Developing Mouse. [PDF]

, 2019
Homomeric α7 nicotinic acetylcholine receptors (nAChRs) are abundantly expressed in the central and peripheral nervous system (CNS and PNS, respectively), and spinal cord.
Broide, Ron S, Chen, Yling, Leslie, Frances M, Winzer-Serhan, Ursula H   +3 more
core   +1 more source

EVALUATING THE GENE EXPRESSION LINKED TO OXIDATIVE STRESS IN THE EYES OF ADULT MALE ZEBRAFISH (DANIO RERIO) AFTER TREATMENT WITH 4 - NONYLPHENOL [PDF]

Exploratory Animal and Medical Research
The phenolic endocrine disruptor molecule 4-nonylphenol (4-NP) is prevalent in several industrial goods and the environment, adversely affecting the health of people, animals, and aquatic organisms. It is necessary to assess the harmful impact of this
Jay K. Desai, Bhavesh J. Trangadia, Urvesh D. Patel, Dixit K. Parasana   +3 more
doaj   +1 more source

The T-cell oncogenic protein HOX11 activates Aldh1 expression in NIH 3T3 cells but represses its expression in mouse spleen development [PDF]

, 1998
Hox11 is a homeobox gene essential for spleen formation in mice, since atrophy of the anlage of a developing spleen occurs in early embryonic development in Hox11 null mice.
Greene, W.K., Bahn, S., Masson, N., Rabbitts, T.H.   +3 more
core   +2 more sources

Glucose-dependent control of insulin like growth factor 2 mRNA binding protein 2 and other gene expressions in ERN1 knockdown glioblastoma cells

Endocrine Regulations
Objective. Endoplasmic reticulum stress and glucose supply are significant factors in glioblastoma growth. The present study aims to investigate the impact of glucose-dependent control of IGF2BP2, TOB1, HBEGF, TWIST1, CCNH, and E2F1 gene expression in ...
Minchenko Oleksandr H., Viletska Yuliia M., Sliusar Myroslava Y., Hnatiuk Oksana S., Ratushna Oksana O., Feldman Taia V., Kozynkevych Halyna E., Bezrodnyi Borys H., Minchenko Dmytro O.   +8 more
doaj   +1 more source