Results 81 to 90 of about 2,221,278 (207)

An agent-based model for mRNA export through the nuclear pore complex. [PDF]

open access: yes, 2014
mRNA export from the nucleus is an essential step in the expression of every protein- coding gene in eukaryotes, but many aspects of this process remain poorly understood.
Azimi, Mohammad   +3 more
core   +2 more sources

Effect of glucose deprivation on the expression of genes encoding glucocorticoid receptor and some related factors in ERN1-knockdown U87 glioma cells

open access: yesEndocrine Regulations, 2019
Objective. The aim of the present study was to examine the effect of glucose deprivation on the expression of genes encoded glucocorticoid receptor (NR3C1) and some related proteins (NR3C2, AHR, NRIP1, NNT, ARHGAP35, SGK1, and SGK3) in U87 glioma cells ...
Riabovol Olena O.   +6 more
doaj   +1 more source

HIF-1α Contributes to Hypoxia-induced Invasion and Metastasis of Esophageal Carcinoma via Inhibiting E-cadherin and Promoting MMP-2 Expression [PDF]

open access: yes, 2012
Hypoxia-inducible factor-1α (HIF-1α) has been found to enhance tumor invasion and metastasis, but no study has reported its action in esophageal carcinoma.
Cheng, Yun-Jie   +7 more
core   +1 more source

Expression of genes encoding IGFBPs, SNARK, CD36, and PECAM1 in the liver of mice treated with chromium disilicide and titanium nitride nanoparticles

open access: yesEndocrine Regulations, 2017
Objective. The aim of the present study was to examine the effect of chromium disilicide and titanium nitride nanoparticles on the expression level of genes encoding important regulatory factors (IGFBP1, IGFBP2, IGFBP3, IGFBP4, IGFBP5, SNARK/NUAK2, CD36,
Minchenko Dmytro O.   +4 more
doaj   +1 more source

Expression of Prolactin Receptor mRNA in Lactotrophs and Somatotrophs of the Chicken Anterior Pituitary Gland

open access: yesThe Journal of Poultry Science, 2018
Prolactin (PRL) is a hormone mainly secreted by the anterior pituitary gland. In birds, PRL exerts a variety of physiological functions in target tissues expressing the PRL receptor (PRLR).
Hiromi Kaneda   +3 more
doaj   +1 more source

Contrasting effects of fluoroquinolone antibiotics on the expression of the collagenases, matrix metalloproteinases (MMP)-1 and -13, in human tendon-derived cells [PDF]

open access: yes, 2005
Fluoroquinolone antibiotics may cause tendon pain and rupture. We reported previously that the fluoroquinolone ciprofloxacin potentiated interleukin (IL)-1ß-stimulated expression of matrix metalloproteinases (MMP)-3 and MMP-1 in human tendon-derived ...
Corps, A.N   +4 more
core   +1 more source

Hypoxic regulation of EDN1, EDNRA, EDNRB, and ECE1 gene expressions in ERN1 knockdown U87 glioma cells

open access: yesEndocrine Regulations, 2019
Objective. The aim of the present investigation was to study the effect of hypoxia on the expression of genes encoding endothelin-1 (EDN1) and its cognate receptors (EDNRA and EDNRB) as well as endothelin converting enzyme 1 (ECE1) in U87 glioma cells in
Minchenko Dmytro O.   +7 more
doaj   +1 more source

Expression of anti-angiogenic genes in subcutaneous adipose tissue of the obese individuals with pre-diabetes and type 2 diabetes

open access: yesБіологічні студії, 2012
Accumulating evidence raises the hypothesis that dysregulation of different intrinsic mechanisms which control most metabolic processes are involved in the development of obesity, metabolic syndrome and type 2 diabetes mellitus, the most profound public ...
O. O. Ratushna   +4 more
doaj   +1 more source

Posttranscriptional regulation of c-fos mRNA expression

open access: yesNucleic Acids Research, 1987
The transient induction of c-fos mRNA and protein suggests that regulation occurs not only by transcriptional activation but also at the level of turnover of the gene product. Here we present evidence for the rapid turnover of c-fos mRNA and some of the requirements for its specific degradation. The half life of induced mature cytoplasmic c-fos mRNA is
Rahmsdorf, H. J.   +5 more
openaire   +3 more sources

Expression of genes encoding IGF1, IGF2, and IGFBPs in blood of obese adolescents with insulin resistance

open access: yesEndocrine Regulations, 2019
Objective. The development of obesity and its metabolic complications is associated with dys-regulation of various intrinsic mechanisms, which control basic metabolic processes via changes in the expression of numerous regulatory genes.
Minchenko Dmytro O.   +3 more
doaj   +1 more source

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