Results 271 to 280 of about 18,476,439 (363)

Concentration and Localization of Coexpressed ELAV/Hu Proteins Control Specificity of mRNA Processing

Molecular and Cellular Biology, 2015
E. Zaharieva, Irmgard U. Haussmann, Ulrike Bräuer, M. Soller   +3 more
semanticscholar   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3. [PDF]

Cell Chem Biol
Tao Y, Budhipramono A, Huang J, Fang M, Xie S, Kim J, Khivansara V, Dominski Z, Tong L, De Brabander JK, Nijhawan D.   +10 more
europepmc   +1 more source

Expression profiling across many samples via manifold-assisted mRNA processing [PDF]

, 2000
Anette Hagberg, Gisela Barbany, Henrik Krook, Martina Samiotaki, Ulf Landegren   +4 more
openalex   +1 more source

Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability.

Molecules and Cells, 2011
N. Mukherjee, D. Corcoran, Jeff Nusbaum, David W. Reid, S. Georgiev, M. Hafner, M. Ascano, T. Tuschl, U. Ohler, J. Keene   +9 more
semanticscholar   +1 more source

Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats

Advanced Biology, EarlyView.
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang, Biying Dong, Jie Chen, Zhenqiang Zhang, Weitong Zeng, Longxiong Liao, Xia Xiong, Xuejun Qin, Xianming Fan   +8 more
wiley   +1 more source

Position-dependent inhibition of the cleavage step of pre-mRNA 3′-end processing by U1 snRNP [PDF]

, 2000
Stéphan Vagner, Ursula Rüegsegger, Samuel Gunderson, Walter Keller, Iain W. Mattaj   +4 more
openalex   +1 more source

Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?

Advanced Biology, EarlyView.
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez, Hao Zhang, Dhananjay Sah, Juan P. Cata   +3 more
wiley   +1 more source

CPSF3 inhibition blocks pancreatic cancer cell proliferation through disruption of core histone mRNA processing. [PDF]

RNA
Alahmari AA, Chaubey AH, Jonnakuti VS, Tisdale AA, Schwarz CD, Cornwell AC, Maraszek KE, Paterson EJ, Kim M, Venkat S, Gomez EC, Wang J, Gurova KV, Yalamanchili HK, Feigin ME.   +14 more
europepmc   +1 more source

Complex cystic fibrosis allele R334W-R1158X results in reduced levels of correctly processed mRNA in a pancreatic sufficient patient

, 1996
Ângela Luzia Branco Pinto Duarte, Margarida D. Amaral, Celeste Barreto, Paula Pacheco, João Lavinha   +4 more
openalex   +1 more source