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In Vitro-Transcribed (IVT)-mRNA CAR Therapy Development

2019
Chimeric antigen receptor (CAR) cancer immunotherapy uses autologous immune system's cells, genetically modified, to reinforce the immune system against cancer cells. Genetic modification is usually mediated via viral transfection, despite the risk of insertional oncogenesis and off target side effects.
Androulla N, Miliotou   +1 more
openaire   +2 more sources

Systemic Administered mRNA as Therapy for Metabolic Diseases

Trends in Molecular Medicine, 2019
The potential of mRNA to produce therapeutic and protective protein levels is a promising approach for the treatment of a large number of diseases. In a recent study published in Nature Medicine (Published online October 8, 2018. doi.org/10.1038/s41591-018-0199-z), the intravenous delivery of human porphobilinogen deaminase (PBGD) mRNA, targeting the ...
Hervé, Puy   +2 more
openaire   +2 more sources

Developing Tomorrow's mRNA-Based Therapies

Genetic Engineering & Biotechnology News, 2022
openaire   +1 more source

mRNA Epi-Drugs: The Possible Use and Potential of mRNA in Radiation Therapy

International Journal of Radiation Oncology*Biology*Physics
mRNA Epi-Drugs: The Possible Use and Potential of mRNA in Radiation ...
Cattaneo, Carlo Guglielmo   +1 more
openaire   +3 more sources

Close the cancer–immunity cycle by integrating lipid nanoparticle–mRNA formulations and dendritic cell therapy

Nature Nanotechnology, 2023
Yuebao Zhang   +10 more
semanticscholar   +1 more source

Novel anti-atherosclerotic mRNA-based therapy

Atherosclerosis, 2022
H. Totary-Jain   +4 more
openaire   +1 more source

Radiation therapy‐associated toxicity: Etiology, management, and prevention

Ca-A Cancer Journal for Clinicians, 2021
Kyle Wang
exaly  

Magnetic resonance linear accelerator technology and adaptive radiation therapy: An overview for clinicians

Ca-A Cancer Journal for Clinicians, 2022
William A Hal, X Allen Li, Daniel A Low
exaly  

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