Results 61 to 70 of about 21,470 (243)

Mapping landowners' willingness to allow recreational deer harvest on their property for managing chronic wasting disease

The Journal of Wildlife Management, EarlyView.
We demonstrate an approach for mapping the probability of landowners' willingness to allow wildlife management actions on their property using chronic wasting disease as a case study. Larger property sizes were associated with higher landowner willingness. We mapped predictions across the contiguous United States at the census tract level.
Eric C. Palm, Matthew A. Williamson, Nathan P. Snow, Sonja Christensen   +3 more
wiley   +1 more source

Knockdown of CREB3L4 Inhibits Autophagy and Reduces Cisplatin Resistance in Gastric Cancer Cells by Downregulating BAG3

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cisplatin resistance remains a major obstacle in the treatment of gastric cancer (GC), and autophagy has been increasingly recognized as a key cytoprotective mechanism contributing to chemoresistance. CREB3L4 is an endoplasmic reticulum membrane‐bound transcription factor that has been shown to regulate the expression of Bcl‐2 associated ...
Wen‐Ke Yin, Xue‐Mei Xie, Xiao‐Yan Song, Yue Xiang   +3 more
wiley   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

NKX2‐1 Downstream Regulatory Structural Variants Explain a Substantial Proportion of Molecular Diagnoses in Patients With Benign Hereditary Chorea

Movement Disorders, EarlyView.
Abstract Background NKX2‐1–related disorders (NKX2‐1‐RDs) classically present with a triad of neurological, endocrine, and pulmonary manifestations, including benign hereditary chorea. However, in a fraction of patients, NKX2‐1 coding variants are not detected, and variants outside the NKX2‐1 locus have been reported.
Robin Wijngaard, Lucy Dougherty‐de Miguel, German Demidov, Galuh Astuti, Amaia Lasa‐Aranzasti, Ana Cueto‐González, Marta Correa‐Vela, Carlos Lázaro‐Hernández, Charlotte A. Haaxma, Clara D.M. van Karnebeek, David Gómez‐Andrés, Ignacio Iglesias‐Serrano, Jiddeke M. van de Kamp, Jolanda Schieving, Laura Trujillano, Marc Engelen, Beatriz Muñoz‐Cabello, Roderick P.P.W.M. Maas, Thatjana Gardeitchik, Victoria Gonzalez, Annemarie de Vreugd, Cristina Pérez‐Sanchez, Elisabet Lloveras, Erik‐Jan Kamsteeg, Maartje Pennings, Natalia Rey‐Viñets, Javier Sánchez, Ronald van Beek, Antonio Moreno‐Galdó, Lisenka E.L.M. Vissers, Kornelia Neveling, Anna Marcé‐Grau, Machteld M. Oud, Belén Pérez‐Dueñas   +33 more
wiley   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source

Artificial Intelligence in Financial Security Markets: Catalyzing Sustainable Development Through Innovation, Risk Mitigation, and Adaptive Governance

Sustainable Development, EarlyView.
ABSTRACT The rapid integration of artificial intelligence (AI) into financial security markets presents both significant opportunities and emerging governance challenges for sustainable development. This study employs a comparative mixed‐methods approach to examine how AI‐driven innovation in trading, risk management, regulatory compliance, and ...
Suleman Bawa, Ibn Wahab Benin, Harika Kancham, Pedro Munoz‐Ramirez   +3 more
wiley   +1 more source

Ed Davey's Tory Removals: The Liberal Democrats and the 2024 General Election

The Political Quarterly, Volume 96, Issue 1, Page 83-90, January/March 2025.
Abstract The 2024 general election represented a remarkable comeback for the Liberal Democrats. Less than a decade on from the coalition and the 2015 election debacle, Sir Ed Davey's party reclaimed third‐party status in the House of Commons with seventy‐two MPs—the largest total for the Liberal Democrats or their Liberal Party predecessors since the ...
Peter Sloman
wiley   +1 more source

Mrp Antiporters Have Important Roles in Diverse Bacteria and Archaea

Frontiers in Microbiology, 2017
Mrp (Multiple resistance and pH) antiporter was identified as a gene complementing an alkaline-sensitive mutant strain of alkaliphilic Bacillus halodurans C-125 in 1990.
Masahiro Ito, Masahiro Ito, Masato Morino, Masato Morino, Terry A. Krulwich   +4 more
doaj   +1 more source

Different Process, Same Outcome? The Problems of Within‐Party Sortition

The Political Quarterly, EarlyView.
Abstract A recent article in Political Quarterly argues for a ‘sortition of candidature’. We show that because political parties are not themselves socially representative, such a scheme would not result in a socially representative Parliament. Drawing on data from the Party Members Project, we show that while some demographic groups would be better ...
Philip Cowley, Paul Webb, Tim Bale
wiley   +1 more source

Government Policy, Low‐ and High‐Skilled Labour, and Technical Inefficiency in Chinese Agriculture, 1952–2008

Journal of Agricultural Economics, EarlyView.
ABSTRACT We utilize Chinese provincial data to explore how government policies affected grain production between 1952 and 2008. We adapt the Caselli‐Coleman framework to allow multiple inputs including fertilizer, land and capital as well as skilled and unskilled labour.
Yulong Chen, Peter F. Orazem
wiley   +1 more source