Results 61 to 70 of about 21,996 (229)

Expression and prognosis analysis of mitochondrial ribosomal protein family in breast cancer

Scientific Reports, 2022
Breast cancer (BC) is characterized by high morbidity. Mitochondrial ribosomal protein (MRP) family participates in mitochondrial energy metabolism, underlying BC progression.
Xiaoyi Lin, Lijuan Guo, Xin Lin, Yulei Wang, Guochun Zhang   +4 more
doaj   +1 more source

Analysis of Notch1 and Notch3 Signaling Pathway Components in Benign Prostatic Hyperplasia and Prostate Cancer Patients

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluates the association between Notch1 and Notch3 genetic variations and serum protein levels in patients with benign prostatic hyperplasia and prostate cancer. While genetic variations showed no significant link to disease risk, serum protein levels were significantly lower in prostate cancer and metastatic groups compared to healthy ...
Emine Yagci, Cansu Ozbayer, Ata Ozen, Gamze Zengin, Hulyam Kurt   +4 more
wiley   +1 more source

Collaborative Autoethnography: A Research Method to Investigate Professional Identity of Medical Radiation Practitioners

Journal of Medical Radiation Sciences, EarlyView.
The professional identity of medical radiation practitioners (MRPs) is evolving in line with the changing healthcare landscape. Collaborative autoethnography offers a feasible qualitative research method to investigate professional identity. ABSTRACT Professional identity (PI) encompasses the values, knowledge, skills and attitudes aligned with an ...
Michelle Fenech, Nadia Mead, Paula Kinnane   +2 more
wiley   +1 more source

Non-immune binding of human IgG to M-related proteins confers resistance to phagocytosis of group A streptococci in blood. [PDF]

PLoS ONE, 2013
The non-immune binding of immunoglobulins by bacteria is thought to contribute to the pathogenesis of infections. M-related proteins (Mrp) are group A streptococcal (GAS) receptors for immunoglobulins, but it is not known if this binding has any impact ...
Harry S Courtney, Yi Li
doaj   +1 more source

Building Research Capacity in Medical Radiation Sciences Through University–Clinical Partnerships: A Commentary on Working Smarter, Not Harder

Journal of Medical Radiation Sciences, EarlyView.
A research partnership model frames university–clinical collaboration as central to strengthening medical radiation sciences research capacity. By aligning students, academics, clinicians, resources, ethics processes, skills development and outputs, the model supports sustainable, evidence‐informed practice with potential benefits for patients and ...
Therese Gunn, Michael Neep, Pamela Rowntree, Deborah Starkey   +3 more
wiley   +1 more source

MRP and inventories

European Journal of Operational Research, 1985
Multi-stage production-inventory systems are considered. Such systems can be described as networks of production stages, separated by inventory points. Inventories may emerge for several well-known reasons, such as lot-sizing, buffering against uncertainty, or anticipating future demand- increases.
Wijngaard, J., Wortmann, J.C.
openaire   +3 more sources

Periodontitis and its association with left ventricular geometry and function: A cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background This study investigated the cross‐sectional association between periodontal status and left ventricular (LV) geometry and function, an early and prognostically relevant marker of cardiovascular disease. Methods Data were drawn from two population‐based cohorts in the Study of Health in Pomerania (SHIP): SHIP‐START‐2 (N = 2333) and ...
Maja Trost, Till Ittermann, Birte Holtfreter, Christiane Pink, Marcus Dörr, Henry Völzke, Matthias Nauck, Marcello Ricardo Paulista Markus, Thomas Kocher   +8 more
wiley   +1 more source

Knockdown of CREB3L4 Inhibits Autophagy and Reduces Cisplatin Resistance in Gastric Cancer Cells by Downregulating BAG3

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cisplatin resistance remains a major obstacle in the treatment of gastric cancer (GC), and autophagy has been increasingly recognized as a key cytoprotective mechanism contributing to chemoresistance. CREB3L4 is an endoplasmic reticulum membrane‐bound transcription factor that has been shown to regulate the expression of Bcl‐2 associated ...
Wen‐Ke Yin, Xue‐Mei Xie, Xiao‐Yan Song, Yue Xiang   +3 more
wiley   +1 more source

NKX2‐1 Downstream Regulatory Structural Variants Explain a Substantial Proportion of Molecular Diagnoses in Patients With Benign Hereditary Chorea

Movement Disorders, EarlyView.
Abstract Background NKX2‐1–related disorders (NKX2‐1‐RDs) classically present with a triad of neurological, endocrine, and pulmonary manifestations, including benign hereditary chorea. However, in a fraction of patients, NKX2‐1 coding variants are not detected, and variants outside the NKX2‐1 locus have been reported.
Robin Wijngaard, Lucy Dougherty‐de Miguel, German Demidov, Galuh Astuti, Amaia Lasa‐Aranzasti, Ana Cueto‐González, Marta Correa‐Vela, Carlos Lázaro‐Hernández, Charlotte A. Haaxma, Clara D.M. van Karnebeek, David Gómez‐Andrés, Ignacio Iglesias‐Serrano, Jiddeke M. van de Kamp, Jolanda Schieving, Laura Trujillano, Marc Engelen, Beatriz Muñoz‐Cabello, Roderick P.P.W.M. Maas, Thatjana Gardeitchik, Victoria Gonzalez, Annemarie de Vreugd, Cristina Pérez‐Sanchez, Elisabet Lloveras, Erik‐Jan Kamsteeg, Maartje Pennings, Natalia Rey‐Viñets, Javier Sánchez, Ronald van Beek, Antonio Moreno‐Galdó, Lisenka E.L.M. Vissers, Kornelia Neveling, Anna Marcé‐Grau, Machteld M. Oud, Belén Pérez‐Dueñas   +33 more
wiley   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source