Results 81 to 90 of about 113,396 (305)

Knockdown of CREB3L4 Inhibits Autophagy and Reduces Cisplatin Resistance in Gastric Cancer Cells by Downregulating BAG3

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cisplatin resistance remains a major obstacle in the treatment of gastric cancer (GC), and autophagy has been increasingly recognized as a key cytoprotective mechanism contributing to chemoresistance. CREB3L4 is an endoplasmic reticulum membrane‐bound transcription factor that has been shown to regulate the expression of Bcl‐2 associated ...
Wen‐Ke Yin   +3 more
wiley   +1 more source

MRP-based negotiation in customer-supplier relationship [PDF]

open access: yes, 2012
In the present uncertain context, increasing the performance of the supply chains requires to define cooperative processes between partners aiming at providing a better answer to the final customer, with a risk shared between partners.
Grabot, Bernard   +2 more
core   +2 more sources

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz   +2 more
wiley   +1 more source

Integrated genomic and transcriptomic approaches reveal oxidative stress adaptation mechanisms in a mesotrione‐resistant Amaranthus tuberculatus biotype

open access: yesPest Management Science, EarlyView.
Integrated GWAS and transcriptomics in a Canadian waterhemp biotype reveal mesotrione resistance is polygenic and metabolically driven. Significant SNPs and 187 herbicide‐responsive genes point to enhanced redox homeostasis, glutathione‐linked detoxification, lipid/secondary metabolism, and oxidative stress responses. Resistance arises from coordinated,
Martin Laforest   +6 more
wiley   +1 more source

Hedging and Standard — MRP [PDF]

open access: yes, 1988
In standard-MRP packages it is possible to use safety stocknorms. In none of the standard-MRP packages however, it is possible to use hedging as an alternative technique for safety stocknorras, although this technique has several advantages from a theoretical point of view. At Eindhoven University of Technology an attempt is made to incorporate hedging
Donselaar, van, K., Wijngaard, J.
openaire   +2 more sources

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo   +5 more
wiley   +1 more source

Space-Frequency Block Code with Matched Rotation for MIMO-OFDM System with Limited Feedback

open access: yesEURASIP Journal on Advances in Signal Processing, 2009
This paper presents a novel matched rotation precoding (MRP) scheme to design a rate one space-frequency block code (SFBC) and a multirate SFBC for MIMO-OFDM systems with limited feedback.
Thushara D. Abhayapala   +4 more
doaj   +1 more source

Formulas of Revised MRP

open access: yesInternational Journal of Engineering Business Management, 2013
Information sharing among supply chain echelons is now an acquired result. As a consequence, most of the traditional techniques and procedures in production management must be revised and updated, exploiting the opportunities provided by new technologies. This paper presents an improved version of Material Requirement Planning procedure, which assumes
Bregni, A   +3 more
openaire   +6 more sources

Ed Davey's Tory Removals: The Liberal Democrats and the 2024 General Election

open access: yesThe Political Quarterly, Volume 96, Issue 1, Page 83-90, January/March 2025.
Abstract The 2024 general election represented a remarkable comeback for the Liberal Democrats. Less than a decade on from the coalition and the 2015 election debacle, Sir Ed Davey's party reclaimed third‐party status in the House of Commons with seventy‐two MPs—the largest total for the Liberal Democrats or their Liberal Party predecessors since the ...
Peter Sloman
wiley   +1 more source

Market risk premium used in 2008: A survey of more than a 1,000 professors [PDF]

open access: yes
The average Market Risk Premium (MRP) used in 2008 by professors in the United States (6.5%) was higher than the one used by their colleagues in Europe (5.3%), Canada (5.4%), the United Kingdom (5.6%) and Australia (5.9%).
Fernandez, Pablo
core  

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