Results 91 to 100 of about 94,450 (307)

Reduced Vancomycin Susceptibility, MRSA and Treatment Failure in Pediatric Staphylococcus aureus Bloodstream Infections

, 2020
Ethan Canty, Benjamin Carnahan, Tara Curley, Emily Anususinha, Rana F. Hamdy, Jessica E. Ericson   +5 more
openalex   +2 more sources

TargetGen‐RNN model discovers novel antibiotic compound targeting drug‐resistant Staphylococcus aureus

Interdisciplinary Medicine, EarlyView.
TargetGen‐recurrent neural network (RNN), an advanced generative model, generated 28,708 unique and novel compounds, identifying SAK‐2970 as a potent antibiotic against drug‐resistant Staphylococcus aureus. Exhibiting strong biofilm inhibition, high therapeutic efficacy, and minimal systemic toxicity in vivo, SAK‐2970 highlights its safety and clinical
Shakeel Ahmad Khan, Adnan Shakoor, Sadia Kanwal   +2 more
wiley   +1 more source

Community-Associated MRSA Infection in Remote Amazon Basin Area, Peru [PDF]

, 2016
Coralith García, Lizeth Astocondor, Jinnethe Reyes, Lina P Carvajal, César A. Arias, Carlos Seas   +5 more
openalex   +1 more source

Advances and challenges in point‐of‐care testing for pathogenic bacteria in battlefield injuries

Interdisciplinary Medicine, EarlyView.
This review explores trauma‐associated bacterial species, summarizes these biosensor advancements, addresses fabrication challenges, outlines future directions, and aims to guide POCT biosensor development for combat/trauma care bacterial detection.
Junjie Fan, Shuai Liu, Dan Luo, Hengjun Zhang, Xianling Dai, Hanqing Xu, Man Shen, Yingchun Huang, Yupeng Long, Ming Chen, Qiaofeng Li, Jing Bao   +11 more
wiley   +1 more source

Achieving superior therapeutic effects on methicillin‐resistant Staphylococcus aureus infection via simple sulfonation process for preparing zwitterionic photosensitizer

Interdisciplinary Medicine, EarlyView.
The sulfonated zwitterionic photosensitizer (PYSO3) is synthesized by reacting maleic anhydride derivatives with 4‐aminopyridine to form PY, followed by sulfonation with 1,4‐butane sultone. It exhibits both photothermal and photodynamic properties, enabling effective eradication of MRSA and biofilms, as well as promoting wound healing in mice ...
Changxu Zhu, Yin Li, Qiyun Deng, Ruixin Guo, Yu Huang, Wenyan Guo, Xi Chen, Ben Zhong Tang, Zhiming Wang, Lidan Chen, Zhaohui Sun   +10 more
wiley   +1 more source

Synergistic activity of melittin with mupirocin: A study against methicillin-resistant S. Aureus (MRSA) and methicillin-susceptible S. Aureus (MSSA) isolates

, 2020
Reza Hakimi Alni, Fatemeh Tavasoli, Amirhomayoon Barati, Shaghayegh Shahrokhi Badarbani, Zahra Salimi, Laleh Babaeekhou   +5 more
openalex   +1 more source

The novel endolysin XZ.700 effectively treats MRSA biofilms in two biofilm models without showing toxicity on human bone cells in vitro

, 2021
Jesse W.P. Kuiper, Jolanda M. A. Hogervorst, Bjorn L. Herpers, Astrid D. Bakker, Jenneke Klein‐Nulend, Peter A. Nolte, Bastiaan P. Krom   +6 more
openalex   +1 more source

Experimental study of impregnation conditions for sustained antimicrobial activity of the original osteoplastic material based on cancellous bone allograft

Гений oртопедии
Introduction Local antibiotic therapy is used to prevent and treat periprosthetic joint infection, but the available antibiotic delivery systems have some limitations.
Alexander P. Antipov, Svetlana A. Bozhkova, Ekaterina M. Gordina, Magomed Sh. Gadzhimagomedov, Andrey A. Kochish   +4 more
doaj   +1 more source

Mortality after broad‐ versus narrow‐spectrum antibiotic treatment for patients with nursing and healthcare‐associated pneumonia: A nationwide retrospective cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Background Nursing and healthcare‐associated pneumonia (NHCAP) is defined as pneumonia occurring in individuals with frequent healthcare contact, such as residents of care facilities or patients with impaired activities of daily living. The effectiveness of broad‐spectrum antibiotics in treating NHCAP remains unclear.
Jumpei Taniguchi, Shotaro Aso, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga   +4 more
wiley   +1 more source

IL CLINICO FRA MRSA E CA-MRSA

Microbiologia Medica, 2006
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openaire   +3 more sources